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Villa holiday rentals in Panama City

Find and book unique villas on Airbnb

Top-rated villa rentals in Panama City

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A welcoming private villa is surrounded by tall trees, showcasing a spacious layout. A swimming pool and trampoline are visible in the backyard, and the exterior features large windows allowing natural light. A green pathway leads to the entrance, emphasizing the serene, forested environment.
Villa in Panamá
4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Top Guest favourite
A modern outdoor area features a turquoise swimming pool surrounded by lush greenery. The space includes a partially covered patio with seating options and an outdoor bar area. Tall buildings are visible in the background against a clear blue sky.
Villa in Santa Cruz De Chinina
5 out of 5 average rating, 33 reviews

5BR House in Panama City w/ Pool & King Beds

Enjoy a family or friends' getaway in this modern, newly remodeled house. This property boasts 5 bedrooms, 4.5 bathrooms, 10 beds, and can comfortably accommodate up to 15 guests. The house also features a private outdoor pool, where you can soak up the sun and cool off on hot days, all while being in a central location, just meters away from malls, supermarkets and night life. It's fully furnished with everything you could possibly need to ensure your stay is as comfortable as possible.

An undercover terrace features comfortable seating arrangements and a swing chair, creating a relaxed environment. Light-colored flooring contrasts with dark wooden ceilings, while lush greenery is visible in the background. An outdoor kitchen area is situated at the rear, enhancing the space for social gatherings.
Villa in Panamá
4.75 out of 5 average rating, 8 reviews

Summit View Guest House Cerro Azul Panama

We have two properties in one estate in Cerro Azul. A guest house as well as an apartment. We are delighted to be able to welcome your entire family, including grandma and grandpa to our slice of paradise. Your experience here promises to be a perfect blend of relaxation, adventure, and breathtaking beauty. Our property boasts a sprawling lower balcony with unparalleled vistas. The guest house and apartment, along with the undercover terrace, pool and spa, are available for your enjoyment.

An aerial view showcases a spacious villa surrounded by lush greenery. The infinity pool reflects the sky, while several guests relax on the patio with vibrant flowers in the foreground, adding color to the scenic setting.
Villa in Panamá
4.82 out of 5 average rating, 57 reviews

Villa La Vista-Panama's majestic mountain hideaway

Welcome to our Villa in Panama's Chagres National Park! We have installed a brand new spa heater in our pool (20Nov24) to enjoy breathtaking views of the surrounding mountain range. Take a dip in our stunning infinity pool, offering picturesque landscapes. Ultimate relaxation during sunset evenings in our inviting hot tub. A gym station you can stay fit. Jefferys Tamarin monkeys at our feeding station. Unwind in a hammock or enjoy a romantic poolside swing. Relax on the outdoor bar stools.

The exterior of a charming villa is displayed, featuring a wooden structure with green windows and doors. A vibrant yellow accent wall highlights the entrance, framed by lush greenery and stone steps leading to the front porch.
Villa in Panamá
4.5 out of 5 average rating, 6 reviews

In the Last Place in the World (6 guests)

Come spend a few days relaxing away from the hustle and bustle. Share as a family or partner of this beautiful and comfortable Villa all for you as a family or partner. Live the experience of having everything in one place to spend a beautiful evening raining or sunny. Comfortable and beautiful space for 6 people. (Adults and children). Located in the Chagres National Park surrounded by greenery but just 45 minutes from the city with a cool/cold climate. You deserve this experience!

Top Guest favourite
A multi-story mansion is showcased overlooking a vibrant swimming pool, adorned with inflatable toys including a pink flamingo and a whale. Bright umbrellas provide shade over red loungers, all set against a backdrop of lush greenery and a partially cloudy sky.
Villa in Panamá
4.97 out of 5 average rating, 65 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

Villa in Panamá

Historic Apartment - Balcony in Old Town

Live the essence of Casco Antiguo in this unique apartment, designed by architect Sebastián Paniza, renowned for his work in the restoration of the Historic District. High ceilings, colonial windows, and wrought-iron railings blend history with modern comfort. From the balcony, enjoy cobblestone streets and colonial façades. The living area, featuring a chandelier-style lamp, open mezzanine, and a functional kitchen, is ideal for those who value design, culture, and a prime location.

Top Guest favourite
Villa in Punta Paitilla
4.98 out of 5 average rating, 94 reviews

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla with 6 bedrooms, 5.5 bathrooms and 8 beds, ideal for up to 16 guests. Enjoy a private pool, an on-site gym, and modern, comfortable spaces designed for families, groups, or business travelers. The layout offers privacy, style, and convenience. Located in one of Panama City’s most exclusive areas, just steps from shopping centers, restaurants, supermarkets, and the Cinta Costera.

Top Guest favourite
A cozy bedroom features a spacious bed with a patterned coverlet, complemented by a bedside table and a lamp. A wardrobe is positioned nearby, and curtain panels frame the window, allowing natural light to filter in. The minimalist decor creates a serene atmosphere.
Villa in Panamá
5 out of 5 average rating, 13 reviews

Villa Helena Studio 1 Apt Cerro Azul

One bedroom cottage with private kitchen and bathroom in a peaceful compound with shared pool. Internet and free parking available. Laundry facilities available for longer stays. Cook your own meals, or have me cook some authentic Caribbean dishes like curries, or use the restaurant available next door. Surrounded by nature and access to trails, waterfalls, rivers, swimming holes.

Guest favourite
A private pool area features a large swimming pool and a smaller hot tub, surrounded by lush greenery. Potted plants and tropical foliage enhance the setting, while a lounge chair is positioned beside the pool. The space is framed by a charming stone wall and an elegant railing.
Villa in Panamá
5 out of 5 average rating, 5 reviews

Villa Helena 2 Bedrooms Cerro Azul

Forget your worries in this spacious and serene space surrounded by nature in a gated community. A home away from home. 2 bedrooms for 4 adults. Your own kitchen, dining/living area, 2 washrooms and 2 bedrooms in a private villa with a pool. Cook your own food, BBQ on a gas grill or check out the restaurants in the community.

A two-story structure displays a soft pink exterior with large glass windows. Lush green landscaping surrounds the entrance, while a driveway leads to a carport featuring a parked vehicle. The property offers unobstructed views of the nearby golf course, enhancing the sense of tranquility.
Villa in Panamá

Pleasant Villa de Playa Villas Decameron Rio Hato

In this accommodation you can breathe tranquility: relax with the whole family, excellent view of the Golf course access to the private beach club we have 24-hour security, quiet place to relax and have fun with the family.

The villa is surrounded by greenery, featuring a two-story structure with distinctive architectural elements. A well-maintained lawn extends in front of the house, while a stone pathway leads to the entrance. Various plants and trees provide a natural setting.
Villa in Panamá
4 out of 5 average rating, 5 reviews

Tranquility and peace connect with Nature 🌤

Descansa en nuestra villa familiar conecta con todo los paisajes dentro de esta propiedad que es parte del Parque Nacional Chagres en nuestra villa te sentiras como en casa a pocos minutod de la ciudad.

Popular amenities for Panama City villa rentals

Quick stats about villa rentals in Panama City

  • Total holiday rentals

    Explore 10 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $119 AUD per night before taxes and fees

  • Verified guest reviews

    Over 340 verified reviews to help you choose

  • Family-friendly holiday rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 10 rentals that welcome pets

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

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