
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
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Best Location – Spacious Luxury Apartment for 8 wi
Welcome to our spacious and elegant apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly in front of one of the most beautiful and lively plazas in the historic district, you’ll be surrounded by top restaurants, cafés, and vibrant city life. The building also features an elevator for your convenience and access to a rooftop pool, perfect for relaxing after a day exploring the city. Its prime location allows you to easily discover the best attract

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Lovely Spacious 3BR in Casco Viejo w/Balcony
Welcome to Casa Bandera, your retreat in the heart of Casco Viejo! Located in Panama's iconic Casco Antiguo, this elegant apartment combines the area's historic charm with modern comfort. It features three cozy bedrooms, each with a private bathroom; an in-house laundry center, a fully equipped kitchen, a living room, and a dining room, perfect for sharing in an exclusive setting. Perfect for up to six people. Enjoy an unforgettable stay in a cozy and fully equipped environment.

Cozy 2 Bedroom w/ Splash Pool
Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

New 2BR apartment, swimming pool, rooftop, views
Welcome to Casa Abes, your retreat in the heart of Casco Viejo! This stylish apartment, newly renovated with soundproof windows and decorated by an international designer, features 2 cozy bedrooms, a balcony overlooking the Iglesia de la Compañía de Jesús, a fully equipped kitchen, living room, dining area, and access to a rooftop with an infinity pool. Perfect for up to 4 guests. Enjoy an unforgettable stay in a warm, fully equipped space.

Luxury apartment in Panama, ocean view
Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Elegant Apt in Costa del Este. Premium Amenities

Apartment with Home Warmth and City View

Old Town & Ocean View

Luxury Centric 2BR Apartment in Casco Viejo

Modern, central and comfortable (001)

Great and modern apartment-Old Town

Casa Korsi Condo, near Historic District

The Captain's Canal View Penthouse
Private apartment rentals

Apto in Financial District (Comfort+Pool+Parking)

Large Apartment in La Cuadra - Casco | By Alura

Apartment with balcony in the Casco Viejo

Apartment Spacious in Clayton

Panoramic Casco Viejo Lookout in The Sands

Balboa Avenue Sky Suites

33rd floor with an amazing view of the ocean, pool + gym + parking

Luxurious apartment in Marbella
Apartment rentals with a hot tub

Suite Luxury 30th View Yoo Panamá & Arts Tower

3 bedroom penthouse with spectacular views!

Apartment between ocean and jungle

Luxury 2BR Suite with Pool & Views

Luxury Beachfront Apartment Near Panama City

New Flat with Ocean + City Views

Coastal View Executive Studio in Panama City

Tropical Paradise at Playa Bonita
Quick stats about apartment rentals in Panama City

Total holiday rentals
Explore 2,890 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $14 AUD per night before taxes and fees

Verified guest reviews
Over 79,200 verified reviews to help you choose

Family-friendly holiday rentals
900 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 1,090 rentals that welcome pets

Holiday rentals with a pool
1,840 properties feature pools

Rentals with dedicated workspaces
1,770 properties have a dedicated workspace

Wi-Fi availability
2,760 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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