
Apartment holiday rentals in Panama City
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Panama City
Guests agree: These apartments are highly rated for location, cleanliness and more.

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

The Penthouse Annex
Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Cozy apartment near Casco Viejo
Enjoy a stay in one of the most exclusive areas in the center of Panama, few minutes from Casco Viejo the Cozy Apartment City Center offers free WiFi, air conditioning and stunning views amidst skyscrapers. The apartment has one bedroom with a queen-size bed, a bath and shower, a sofa bed, two smart TV, a fully equipped kitchen, a washer and dryer, and a half bath. On the property there is a work area, a gymnasium, a community pool, and a barbeque area FREE PARKING

Escape to the Heart of Casco with a Private Balcony
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Modern and Central · Nice Condo in the Heart of Pty
¡Modern 50 m2 apartment located on Calle 50, in the heart of Panama City!. With access to the best in art, culture, business, finance, sports, shopping, food, and nightlife. * The space has a room with a queen size bed, full bathroom, smart TV and desk with monitor (HDMI cable) for those traveling without disconnecting from work. * The living room has a comfortable sofa bed, full bathroom, dining room and kitchen equipped for kitchen lovers!.

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Jacuzzi in colonial ruins in beautiful apartment
Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Elegant apartment with a view & the warmth of home
This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Beautiful apartment in Casco Viejo
Located in the heart of Casco Viejo, you can enjoy the sunset with views of the city, the sea and the canal, from its rooftop. The building's ground floor is home to La Cuadra Market where there are a variety of renowned restaurants with different styles of food, as well as a bar. Close to everything, you can walk around everything and enjoy every place it offers you.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Unique industrial style condo for 2. Downtown

Chic & Modern 1BD Yoo Panama City

Unique Luxury 3-story Loft at the Yoo

Central Casco Escape with Charming Balcony

Comfortable apartment in the heart of Obarrio

YOO Panama · Luxury signature ocean view. 57th fl

Exclusivo Apto/Av Balboa/Pool/Gym/AC/View/Parking

Apartment 61B YOO Ocean View on Balboa Avenue
Private apartment rentals

Aesthetic Apt with Amazing City Skyline View

new apartment in the heart of Panama

Beautifull 1BR Apt With Comfy Hotel Linens

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Brand new spectacular 1B 1B Apartment

Suite Luxury 30th View , Cinta Costera Panama

Apartamento Av. Balboa, Yoo&Arts

Comfortable apartment
Apartment rentals with a hot tub

Luxury Apartment in Panama | 2BR + Views + Pool

2BR/AP PH Yoo 44i – Apartment with Sea View

Spacious Oceanfront Apartment

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Coastal Chic Executive Studio in Panama City

5A - Boutique Apartment ! High end furnished! 4BR

BusinessTripFlat/Comfy/well located/AAs/Queen beds
Quick stats about apartment rentals in Panama City

Total holiday rentals
Explore 2,770 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $15 AUD per night before taxes and fees

Verified guest reviews
Over 71,040 verified reviews to help you choose

Family-friendly holiday rentals
850 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 990 rentals that welcome pets

Holiday rentals with a pool
1,730 properties feature pools

Rentals with dedicated workspaces
1,720 properties have a dedicated workspace

Wi-Fi availability
2,640 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Destinations to explore
- Cartagena Holiday rentals
- San Andrés Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Uvita Holiday rentals
- Boquete Holiday rentals
- Coveñas Holiday rentals
- Playa Blanca Holiday rentals
- Ancón Holiday rentals
- Bahía Ballena Holiday rentals
- Limón Holiday rentals
- Valle de Antón Holiday rentals
- David Holiday rentals
- Rentals with a fire pit Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Boutique hotels Panama City
- Rentals with a sauna Panama City
- Pet-friendly rentals Panama City
- Beachfront rentals Panama City
- Fitness-friendly rentals Panama City
- Rentals with a hot tub Panama City
- Cabin rentals Panama City
- Hostel rentals Panama City
- Rentals with an accessible height bed Panama City
- Private suite rentals Panama City
- Loft rentals Panama City
- Rentals with breakfast Panama City
- Waterfront rentals Panama City
- Villa rentals Panama City
- Guesthouse rentals Panama City
- Rentals with outdoor seating Panama City
- Rentals with a patio Panama City
- Rentals with a washing machine and dryer Panama City
- House rentals Panama City
- Rentals with lake access Panama City
- Smoking-friendly rentals Panama City
- Rentals with beach access Panama City
- Hotel rooms Panama City
- Serviced apartment rentals Panama City
- Condo rentals Panama City
- Rentals with an EV charger Panama City
- Rentals with a home theatre Panama City
- Rentals with pools Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Townhouse rentals Panama City
- Apartment rentals Panama
- Things to do Panama City
- Sports activities Panama City
- Sightseeing Panama City
- Art and culture Panama City
- Tours Panama City
- Nature and outdoors Panama City
- Food and drink Panama City
- Things to do Panama
- Sports activities Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Entertainment Panama




