
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
Guests agree: These apartments are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Elegant Apt - View to Main Plaza of Casco Viejo
Experience the charm of Casco Viejo with this beautiful apartment, located in the heart of the historic neighborhood - close to many dining options, cafes, supermarkets and attractions. Enjoy the stunning views of the Main Plaza from the comfort of your balcony or rest easy inside with the soundproof doors and strong WIFI connection. We provide a water biden throughout your stay for hydration and Panamanian coffee renowned as one of the best in the world, at the moment of check in.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Large Apartment in La Cuadra - Casco | By Alura
El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Luxury apartment in Panama, ocean view
Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Cozy Studio in Cinta Costera with Home Vibes
✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Ocean View on Avenida Balboa
Enjoy breathtaking views, a spectacular oceanfront infinity pool, and direct access to the Poin Panama resort, as well as a variety of dining and bar options for an unparalleled vacation experience. This spacious and cozy apartment is ideal for families, couples or travelers looking for an unforgettable getaway. Book now and start your adventure in this urban oasis!
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Beautiful apartment in Casco Viejo ST. George D

Cozy apartment in Panama

Oceanview 1BR in Yoo Panama

Modern condo with an ocean view and a hanging chair

Suite Luxury 30th View , Cinta Costera Panama

Apartment 20B YOO Ocean View on Balboa Avenue

Cozy apartment with amazing views

On the beach. Entire floor with oceanfront terrace
Private apartment rentals

New apartment in the heart of Panama

Beautifull 1BR Apt With Comfy Hotel Linens

Centrally located apartment.

Comfortable apartment in the heart of Obarrio

Serena House Obarrio by God Housing

Where I'm happy in Panama City

Coastal Chic Executive Studio in Panama City

Cozy Ocean-view Retreat Panama
Apartment rentals with a hot tub

Apartment between ocean and jungle

Luxury Apartment in Panama | 2BR + Views + Pool

Luxury Beachfront Apartment Near Panama City

PH Yoo 44i – Ocean View Apartment

New Flat with Ocean + City Views

Spacious Oceanfront Apartment

Tropical Paradise at Playa Bonita

Panama Dream View Escape
Quick stats about apartment rentals in Panama City

Total holiday rentals
Explore 2,890 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $15 AUD per night before taxes and fees

Verified guest reviews
Over 79,200 verified reviews to help you choose

Family-friendly holiday rentals
900 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 1,090 rentals that welcome pets

Holiday rentals with a pool
1,840 properties feature pools

Rentals with dedicated workspaces
1,770 properties have a dedicated workspace

Wi-Fi availability
2,760 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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