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Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: These apartments are highly rated for location, cleanliness and more.

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Guest favourite
A modern living area is presented with a light-colored sofa and stylish accent cushions. A glass coffee table is paired with a white armchair and a vibrant blue side table. Floor-to-ceiling windows provide a clear view of the ocean and allow natural light to brighten the space.
Apartment in Bella Vista
4.79 out of 5 average rating, 129 reviews

Apartment Av. Balboa, Yoo&Arts

Accommodation with the best ocean view in Panama, Yoo & Arts Building, 130 meters. You can enjoy various environments during your stay, have breakfast on our balcony with an exceptional ocean view, watch the sunrise from your bedroom, or even work in an excellent environment. You can have easy access to haute cuisine restaurants in the same building as the accommodation, supermarkets nearby, shopping malls. Luxury will be all around you as the building is one of the most exclusive in the area.

Top Guest favourite
Apartment in Panamá
4.94 out of 5 average rating, 145 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Superhost
A charming historic building features ornate white architecture with teal accents. Arched windows and balconies are visible on the upper levels, showcasing decorative wrought-iron railings. The entrance showcases double doors, inviting passersby to explore the structure's elegance.
Apartment in San Felipe
4.83 out of 5 average rating, 182 reviews

Best location - Unique and charming loft

Relax and enjoy the elegance of a bygone era when you stay in this charming Loft. Carefully built with wooden floors, calicanto walls, high beamed ceilings and antique details for a luxurious yet charming feel. Take an early morning walk and enjoy the ruins, churches, and museums of Casco Viejo. Stroll through the historic streets while the city sleeps, then return for morning coffee in this classic and elegant Loft with a dreamy terrace. This apartment is located in the heart of Casco Viejo!

Top Guest favourite
Apartment in Bella Vista
4.97 out of 5 average rating, 119 reviews

Apt with unique views to remember

Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Superhost
A spacious outdoor area features wooden dining tables surrounded by potted plants. The space includes a plunge pool, comfortable seating, and a hammock for relaxation, with views of the nearby structures and the sky above.
Apartment in San Felipe
4.87 out of 5 average rating, 397 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Top Guest favourite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Apartment in San Felipe
4.96 out of 5 average rating, 109 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Top Guest favourite
Apartment in San Felipe
4.97 out of 5 average rating, 116 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, you will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. This restored- colonial building was built in the year 1850, and features some of the original "calicanto" walls. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Top Guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in San Felipe
4.98 out of 5 average rating, 187 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top Guest favourite
An expansive infinity pool reflects the skyline of Panama City and the nearby bay. Lounge chairs are arranged neatly along the poolside, allowing for relaxation while enjoying the panoramic views of the surrounding area.
Apartment in Panama City
4.93 out of 5 average rating, 117 reviews

Impressive ocean and Panama City views

Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Guest favourite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Apartment in Bella Vista
4.93 out of 5 average rating, 131 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Top Guest favourite
A modern living area features a white sectional sofa adorned with colorful cushions. A sleek coffee table sits in front of a mounted television. Large windows provide expansive views of the city skyline, enhancing the bright and airy feel of the space.
Apartment in Bella Vista
4.89 out of 5 average rating, 182 reviews

Beautiful Apt, Best Location 2BR

Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Apartment in San Felipe
4.92 out of 5 average rating, 116 reviews

The best view of the Old Town

Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll have a wide variety of restaurants and shops at your disposal, where you can buy souvenirs of this wonderful trip.

Popular amenities for Panama City apartment rentals

Quick stats about apartment rentals in Panama City

  • Total holiday rentals

    Explore 2,860 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $14 AUD per night before taxes and fees

  • Verified guest reviews

    Over 88,500 verified reviews to help you choose

  • Family-friendly holiday rentals

    920 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 1,130 rentals that welcome pets

  • Holiday rentals with a pool

    1,940 properties feature pools

  • Rentals with dedicated workspaces

    1,910 properties have a dedicated workspace

  • Wi-Fi availability

    2,790 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore