Some info has been automatically translated. Show original language

Vacation rentals in Panama City

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favourite
Condo in Panama
Patty’s Cozy & Quiet Studio with K-bed in Casco
*TOTALLY renovated on NOV 15th 2023: new floors, modern bathroom, new design & art work* Photos to come! Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen beside from the main living space. It is spacious, comfortable and tastefully decorated!
16 – 23 Sept
4.99 out of 5 average rating, 200 reviews
Guest favourite
Apartment in Panamá
Cozy n Comfy con balcón in the heart of Casco
Remodelado, cómodo y céntrico alojamiento en el corazón de Casco Viejo, pintoresco lugar declarado Patrimonio de la Humanidad por la UNESCO. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. Podrás explorar la zona a pie, el apartamento esta completamente remodelado, un balcón espectacular, cocina full equipada, camas cómodas, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar-Smart tv -Cocina full equipada -1.5 baños -Balcón con vistas
23 – 30 Nov
5.0 out of 5 average rating, 51 reviews
Guest favourite
Apartment in Panamá
Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.
17 – 24 Jan
4.86 out of 5 average rating, 257 reviews

Popular amenities for Panama City holiday rentals

Stay near Panama City's top sights

Albrook Mall132 locals recommend
Multiplaza Panamá147 locals recommend
Causeway Amador67 locals recommend
AltaPlaza Mall38 locals recommend
Atlapa Convention Center15 locals recommend
Sheraton Grand Panama5 locals recommend

Other great holiday rentals in Panama City

Guest favourite
Condo in Panamá
CASA SAEMA -PRESTIGIOSO PENTHOUSE DUPLEX WITH TERRACES
6 – 13 Nov
4.94 out of 5 average rating, 69 reviews
Guest favourite
Apartment in Panama City
Luxury Mid-Century Apartment In Casco Viejo
28 Aug – 4 Sept
5.0 out of 5 average rating, 14 reviews
Guest favourite
Villa in Panamá
Beautiful House in Panama w/ King Beds + Pool
27 July – 3 Aug
4.98 out of 5 average rating, 44 reviews
Guest favourite
Condo in Panamá
Spacious Executive 37th-Floor Quiet Apartment
21 – 28 Apr
4.98 out of 5 average rating, 42 reviews
Guest favourite
Apartment in Panamá
Beautiful apartment in Casco Viejo
2 – 9 Sept
4.85 out of 5 average rating, 26 reviews
Superhost
Apartment in Panamá
Loft in Casco Viejo
1 – 8 Aug
4.78 out of 5 average rating, 40 reviews
Guest favourite
Cottage in Panamá
Modern House in Altos de Cerro Azul with 2 rooms
9 – 16 Apr
4.94 out of 5 average rating, 16 reviews
Superhost
Apartment in Panama City
Lovely place in Via Argentina
4 – 11 May
4.9 out of 5 average rating, 94 reviews
Guest favourite
Villa in Panamá
Breathtaking Views Mansion w/King Beds
31 Jan – 7 Feb
5.0 out of 5 average rating, 27 reviews
Guest favourite
Apartment in Panamá
Luxury Apartment Panama Centro, Banking Area
24 – 31 Aug
5.0 out of 5 average rating, 16 reviews
Guest favourite
Apartment in Panamá
Top luxury apartment in the sea PH yoo, Av Balboa
28 Aug – 4 Sept
4.82 out of 5 average rating, 28 reviews
Guest favourite
Apartment in Panamá
Luxurious Penthouse with Panoramic Ocean Views.
7 – 14 Nov
4.85 out of 5 average rating, 74 reviews

Quick stats about holiday rentals in Panama City

Total rentals

4.2K properties

Rentals with dedicated workspaces

2.3K properties have a dedicated workspace

Rentals with a pool

2.3K properties have a pool

Pet-friendly rentals

1.3K properties allow pets

Family-friendly rentals

1.4K properties are a good fit for families

Total number of reviews

70K reviews

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama City