
Holiday houses in Panama City
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Top-rated holiday rentals in Panama City
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In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Luxury oceanfront apartment on the coastal strip
Apartamento contemporáneo en uno de los edificios mas lujosos de Panamá, ubicado en la Cinta Costera frente al mar, muy cerca de restaurantes, centros comerciales, cafe's, tiendas, supermercados y sitios turísticos de la ciudad Con su inmejorable ubicación y máximo confort, los huéspedes se pueden desconectar, relajarse y saborear este destino mágico que tiene su propio estilo, ademas de las instalaciones del edificio como Spa, restaurantes, gym, piscina, bar, billar, valet parking, entre otros

Colonial Luxury Apartment – Best Location in Old T
Welcome to our spacious colonial-style apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly across from one of the most beautiful plazas in the historic district, you’ll be surrounded by renowned restaurants, cafés, and vibrant city life. The building features an elevator for your convenience and access to a rooftop terrace with a swimming pool, where you can enjoy stunning views of Casco Antiguo. Its prime location allows you to explore all the

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Luxury Balcony Stays + Pool Casco Viejo
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Comfortable and luxurious apartment
Enjoy a stylish experience in our accommodation in the Old Town, take advantage of the location close to art galleries, restaurants, crafts, etc. Our house has three bedrooms each with a balcony, bathroom and closet, with a nice contemporary equipped kitchen; a large living and dining room, work area. You have a total area of 326 m² The whole house is surrounded by balconies where you can enjoy panoramic views.

Patty’s Bay View Home @ the Causeway with bikes
Beautiful and well-appointed spacious 1-bedroom condo featuring a large bathroom & fully stocked kitchen. Gorgeous Ocean views onto Casco Viejo, downtown Skyline & lush hills of Ancon as a background. Enjoy the Canal views, with ships, from the common roof top terraces. Its close location by the Causeway, Casco Viejo & down town makes it the perfect "pied à terre".

Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
Popular amenities for Panama City holiday rentals
Other great holiday rentals in Panama City

w* | Whimsical 1BR in Plaza Catedral

Most Beautiful Loft in the Heart of Casco Viejo

Casco Viejo 2BR Loft • Rooftop Pool Gym & Balcony

Luxurious and comfortable apartment in Cinta Costera

Centric - 2BDR Apt - Old Town

Casco Antiguo Apartment with Balcony & Stone Wall

Casa Condal - Your Private Nature Eco-Retreat

Wanders&Yoo Luxury 1BR with F&F Tower view
Frequently Asked Questions
What are the best places to stay in Panama City?
Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.
What are the best things to do in Panama City with kids?
Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.
What are some of the best things to do in Panama City?
Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.
How is the weather in Panama City?
Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.
What are the best places to visit in Panama City?
Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.
What are some hiking trails in Panama City?
Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.
What are some family activities we can do in Panama City?
Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.
What are some of the best day trip ideas from Panama City?
Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.
Are there any pet friendly accommodations available in Panama City?
Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.
What are some local tips for visiting Panama City?
When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.
What is Panama City known for?
Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.
What are the best hidden gems to explore in Panama City?
Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.
What are the best foods to try in Panama City?
Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.
What should I bring for a trip to Panama City?
Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.
What is the nightlife in Panama City like?
Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.
What are the most popular events or festivals in Panama City?
Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.
Are there family friendly vacation rentals in Panama City?
Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.
When is the best time to visit Panama City?
The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.
Quick stats about holiday rentals in Panama City

Total holiday rentals
Explore 5,060 holiday rentals in Panama City

Verified guest reviews
Over 136,790 verified reviews to help you choose

Family-friendly holiday rentals
1,660 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 1,880 rentals that welcome pets

Holiday rentals with a pool
2,750 properties feature pools

Rentals with dedicated workspaces
3,190 properties have a dedicated workspace

Wi-Fi availability
4,860 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Self check-in, Gym and BBQ grill across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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