
Family-friendly holiday rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Panama City
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Best Location – Spacious Luxury Apartment for 8
Welcome to our spacious and elegant apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly in front of one of the most beautiful and lively plazas in the historic district, you’ll be surrounded by top restaurants, cafés, and vibrant city life. The building also features an elevator for your convenience and access to a rooftop, perfect for relaxing after a day exploring the city. Its prime location allows you to easily discover the best attractions

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

CASA SAEMA "C" -Design Apt, Casco Viejo Panama
Hermoso Apto en Panamá Casco antiguo, renovado con materiales de primera calidad, diseño exclusivo y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina con lavavajillas y lavadora, El edificio cuenta con una piscina en patio central compartida Aptos, portero 24-7, gran variedad de ocio en la zona, no se permiten niños que no sepan nadar.
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Luxury Apartment With Private Beach And Sea View

Cabin near the city, luxurious treehouse

Apartment Av. Balboa, Yoo&Arts

New Flat with Ocean + City Views

Unique Historic House in Casco

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Luxury Suite 18th View Coco del Mar Panama
Family- and pet-friendly home rentals

Mountain Retreat

Cozy Casco Viejo Apartment

Elegant Apt in Costa del Este. Premium Amenities

Exclusive apartment in Calzada de Amador

Great and modern apartment-Old Town

Private parking & rooftop | Studio Casco Center

Cozy 2 Bedroom w/ Splash Pool

Modern and elegant apartment in Cinta Costera
Family-friendly home rentals with a pool

Cozy 1BR•Balcony Gym Rooftop Pool•Near Multiplaza

Modern studio with ocean view / central / prime

VIP Suite/ Sea View + Pool & Sky Lounge + Gym

Cerro Azul, Country House with Heated Pool.

The Gray calle 50 muy céntrico, a 5 min estación.

59A apartment with panoramic view, with 2 bedrooms

Casa Vidal - The Only House in Casco Viejo

"Arrive as guests. Leave feeling at home".
Quick stats about holiday rentals that are family-friendly in Panama City

Total holiday rentals
Explore 1,660 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $14 AUD per night before taxes and fees

Verified guest reviews
Over 49,930 verified reviews to help you choose

Pet-friendly accommodation
Find 710 rentals that welcome pets

Holiday rentals with a pool
930 properties feature pools

Rentals with dedicated workspaces
1,020 properties have a dedicated workspace

Wi-Fi availability
1,590 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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