
Family-friendly holiday rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in Panama City

Total holiday rentals
Explore 1,780 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $14 AUD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly accommodation
Find 760 rentals that welcome pets

Holiday rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
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CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular Duplex penthouse in Panama Old Town, 265 M2 with balconies, private outdoor terraces, has an interior garden room, a dining room, 3 rooms (+ sofa bed in studio), recently renovated with Loft concept, unique and comfortable exclusive design, in the best area of the Old Town, perfect for relaxing and disconnecting, kitchen, dishwasher, room with washing machine. Shared pool, elevator, 24-7 doorman, children who do not know how to swim are not allowed, great variety of leisure in the area.
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Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!
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Round House River Dreams Cerro Azul
Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.
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The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
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Colonial style with calicanto and a private balcony
Welcome to a cosy apartment where the charm of the calicanto walls blends with warm details and a perfect balcony to enjoy the atmosphere and the view of the Old Town. We are in a prime location on one of the main avenues of the Casco. From here, you can easily access historical sites, restaurants, cafes, bars and charming spots. The idea is for you to arrive, feel comfortable and enjoy the city at your own pace, whether you're alone, with your partner or with your family.
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Late check-in • Solo or groups up to 6 •Shuttle
✈️ Spacious apartment just 10 minutes from Tocumen Airport. Perfect for layovers, early flights, late arrivals, families, and groups of up to 6 guests. 🛏️ Comfortable beds ❄️ Air conditioning 📶 Fast WiFi 🚿 Hot water 🍽️ Fully equipped kitchen 🚐 Airport transportation available 🔐 Easy check-in with step-by-step instructions 🚗 Safe gated community 📍 Great location for layovers, San Blas tours, and short stays. 💬 Fast communication before and during your stay.
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Studio apartment in the heart of Casco
Welcome to Casa Pérez, your retreat in the heart of the Old Town! Enjoy a prime location and the best views from a spectacular private balcony facing the most iconic square in the Casco. Ideal for 3 people, this cozy and bright one-bedroom apartment includes Wi-Fi, air conditioning, living room, dining room, equipped kitchen, washing machine and elevator for your comfort. Enjoy an unforgettable stay in a warm and fully equipped atmosphere.
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Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.
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Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
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The best view of the Old Town
Welcome to this charming accommodation in the heart of the Old Town, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you'll enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you'll have a wide variety of restaurants and shops at your disposal, where you can buy souvenirs of this wonderful trip.
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Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
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Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
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Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...
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Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms
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Unique Historic House in Casco
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New Flat with Ocean + City Views
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Tropical Paradise at Playa Bonita
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Mountain Retreat
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Apartment in Obarrio with rooftop|Pool and view
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Family- and pet-friendly home rentals

Beautiful Apartment on High Floor, Beautiful Views
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Luxury apartment in downtown Panama, banking area
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Beautiful House in Panama w/ King Beds + Pool
Indoor spacesKitchenAir conditioning

Luxury Apartment | Walk to Restaurants & Shops
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Private parking & rooftop | Studio Casco Center
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Luxury Centric 2BR Apartment in Casco Viejo
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Sunrise by the sea / The Sands
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Panoramic Casco Viejo Lookout in The Sands
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Family-friendly home rentals with a pool

The Sands, Beautiful Apartment
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Walk to Everything | Luxury Stay in Casco Viej
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Luxury apt in Panama City 2 Rooms 3 Baths
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Bright Designer Residence w/ Skylight + Rooftop
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Panoramic Ocean View | The Sands
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Panama City Sea View
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GreatCanal-Front Luxury 3BR | City & Golf View 401
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The best view and location in Panama City
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