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Villa holiday rentals in Panama

Find and book unique villas on Airbnb

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Popular amenities for Panama villa rentals

Private villa rentals

Guest favourite
Villa in Chame District
4.95 out of 5 average rating, 22 reviews

Villa at Caracol Beach 3 bed (V4-PBA)

JulianeRating, 5 stars1 month ago
Very nice apartment with excellent location in Playa Caracol, close to the pool and the beach. The villa is well equipped with kitchen and baby and children stuff.
Guest favourite
Villa in Playa Venao
4.93 out of 5 average rating, 41 reviews

Villa La Piragua: 3BR Surfside Retreat: 5-7G

OrinRating, 5 stars1 week ago
The Villa is amazing! It is huge there’s loads of beds and a very nice sonos sound system, plus the hosts were extremely nice and helpful! Will be back if we’ll come to venao again ❤️
Villa in Panamá
4.81 out of 5 average rating, 53 reviews

Villa La Vista-Panama's majestic mountain hideaway

DarienRating, 5 stars1 week ago
Amazing place with a beautiful view of Panama City. We enjoyed our stay and would definitely come back again next time we are in Panama.
Villa in Isla Cristóbal
5 out of 5 average rating, 5 reviews

Bocas Overwater Luxury Villa & Lodge

SteveRating, 5 stars2 months ago
Absolutely incredible stay! The villa in Bocas del Toro was everything we dreamed of and more. Captain Eric was a true gem—always making sure we had a boat ready whenever and wherever we wanted to go. His local knowledge and friendly vibe made every outing seamless and fun. The chefs were outstanding, treating us to delicious breakfasts each morning that started our days off perfectly. Between the stunning views, top-notch service, and warm hospitality, this place is a slice of paradise. Five stars all the way!
Villa in San José
5 out of 5 average rating, 7 reviews

Beachfront Property is Your Own Piece of Paradise

FredRating, 5 stars5 months ago
perfect place to stay. beautiful house , huge garden, great outdoors and views. you feel at home with Lorenzo taking great care of the house, the guests and breakfast and lunch. Ask him to get you fish and seafood from local fishermen. Lorenzo can even organize a transfer to the airport for example. on site you just have to go to the supermarket. As there is a big scam on car rentals at the airport, better take a Uber and local taxis when at the house. The place is so wonderful you will stay at home all the time. For toddlers Andres, our host, has everything to play with. We really felt home and 12 days seemed to be a week end. So smooth. Andres, the host, is always pending of your needs, how you feel... before travelling, during your stay, etc. Great host indeed
Villa in Cambutal
5 out of 5 average rating, 4 reviews

Casa Almendra

Jake And KristinRating, 5 stars1 month ago
There are no words to describe how amazing our stay in Cambutal was! I can’t think of any place I would rather wake up and drink coffee. Mike was the best host and made us feel so welcome and at home. The house is gorgeous and our kids loved the pool and tide pools out front. The beach is so beautiful and we rarely saw another person there, which is exactly what we wanted. It was also such a treat eating, hanging out and getting the best massage ever at Sansara. All was so dang relaxing and good for the soul. We already can’t wait to come back!
Superhost
Villa in Playa Coronado
4.59 out of 5 average rating, 27 reviews

VILLA ROMA

VeronicaRating, 5 stars6 months ago
Mayra was very responsive. Place is as advertised. A few things were reported to be fixed, mostly for next visitors, but nothing that impacted our time there. There is a beach access nearby, but I recommend to go to Playa Serena instead (8mins drive); as I traveled with elders and is a long path to walk.
Superhost
Villa in Boquete
4.86 out of 5 average rating, 28 reviews

Mountain 3B villa with breathtaking views

AidaRating, 5 stars2 months ago
I felt like home , beautiful place… an Amazing view … I could stay forever !!! 😻. Love it 🥰

Luxury villa rentals

Superhost
Villa in Playa Venao
4.8 out of 5 average rating, 56 reviews

Villa Nomada -Barefoot Luxury Beach Front Villa

RobertRating, 5 stars1 month ago
Me and my two brothers rented this place for a 5 day stay so we could take our father (82 years old) on some easy fishing trips around the local islands and stare out at the beach all day in the afternoons. This property did not disappoint one bit. From the flow of the layout designed to have a central courtyard-with-overhang, to the beautiful kitchen and the serene pool. All topped off by the gorgeous view of the beach 50 yards away, this was about as picturesque of a vacation home as it gets. There's nothing else like it (as of now) in Playa Venao. Design, service, and relaxation of the highest order. 10/10. We tried to contact the owner about renting it for a year after our short stay and as it so happens, someone else already had the same idea. Gorgeous home, excellent staff. Perfect stay.
Guest favourite
Villa in Las Lajas
4.83 out of 5 average rating, 35 reviews

Beach House Where Emy

OsirisRating, 5 stars2 weeks ago
It's a great place to spend time with the family. Everything was clean and cozy😍
Guest favourite
Villa in Punta Paitilla
4.98 out of 5 average rating, 82 reviews

Beautiful House in Panama w/ King Beds + Pool

ZackRating, 5 stars2 weeks ago
5 Stars – Great Stay! Our group of 8 had an amazing time at Jonathan’s place. The home was spacious, clean, and perfectly set up for a group our size. The location couldn’t have been better — just a 1-minute walk to two grocery stores, excellent coffee shops, and a variety of restaurants. Jonathan was an outstanding host — extremely responsive and helpful as a few needs came up during our stay. He handled everything quickly and made sure we were comfortable the entire time. Would absolutely recommend this home to anyone visiting Panama!
Guest favourite
Villa in Rio Hato
4.86 out of 5 average rating, 44 reviews

La Casa de las Uvas, an oasis with ocean views

LoriRating, 5 stars3 months ago
Wonderful stay. The pool, beautiful trees and well thought out outdoor seating was the perfect setting for our large family to vacation. Easy walk to the beach and restaurants. House had everything we needed. Mónica was very responsive to a very small issue we had and it was quickly remedied. Absolutely recommend.
Guest favourite
Villa in Maria Chiquita
4.93 out of 5 average rating, 44 reviews

Cozy Villa in Playa Escondida

YeimyRating, 5 stars1 week ago
Gloria is a very attentive and thoughtful host! The villa has everything you need to go to the beach and for the bbq, in addition to being very clean. The beach is a 2-minute walk away, in general I recommend going to Playa Escondida if you are looking for comfort, tranquility and privacy!
Top Guest favourite
Villa in Boquete
5 out of 5 average rating, 22 reviews

Luxury Loft in 5-Star Resort | King | Deck | Views

WeihongRating, 5 stars1 week ago
I had a fantastic stay at Joseph’s place! The space was exactly as described—clean, comfortable, and thoughtfully designed. Check-in was smooth, and communication with Joseph was prompt and friendly throughout. The location was convenient and quiet, making it easy to relax and recharge. I really appreciated the small touches that made the stay feel extra welcoming. Would definitely recommend and hope to stay again!
Superhost
Villa in Isla Colon
4.9 out of 5 average rating, 10 reviews

Casa Caracola. Luxury villa. 200 mts from beach

GiyoraRating, 5 stars3 months ago
Our stay at casa Caracola was simply exceptional. It is a spacious, luxurious and perfect for two families. From the moment we arrived, we felt so comfortable that we hardly needed to go anywhere. We spent our days enjoying the beautiful garden and swimming pool, where we had the privilege of seeing toucans, monkeys, and a variety of wild birds. Waking up each morning to the sound of birds singing was an incredible experience. The host, Ricardo, was outstanding. He helped us arrange everything, from private chefs who prepared spectacular meals at the house to booking tours and surf and diving lessons. His attention to detail and willingness to assist made our stay even more special. We also want to highlight Nely, who took care of keeping the house spotless throughout our stay. It was a pleasure to have her help in maintaining everything clean and organized. We will definitely be back. A perfect place for an unforgettable getaway! Thanks Gigi
Top Guest favourite
Villa in Panamá
4.98 out of 5 average rating, 54 reviews

Breathtaking Views Mansion w/King Beds

MelissaRating, 5 stars1 week ago
The home is breathtaking and the host was so gracious. When we arrived, we were met by Dario who welcomed us and gave us a tour. There are four floors of amazing space and you feel like you are in a palace. We enjoyed the pool, media room, and billiard room and were surprised to see the mini-golf on the 4th floor. There are patios everywhere and the views are stunning. There are plenty of supplies for cooking and the dining room comfortably seats 8. We highly recommend this home, and we hope to return. Thank you Bradley and Dario for a fabulous experience!!

Villa rentals with a pool

Top Guest favourite
Villa in Contadora Island
4.96 out of 5 average rating, 25 reviews

Cheerful 2-bedroom villa with shared pool

ClementRating, 5 stars2 months ago
The villa is of very good quality, well maintained with recent high-end amenities. The photos do not honor the villa. Maurice and Jean are very responsive and do everything to make the stay as pleasant as possible. We enjoyed the stay!
Superhost
Villa in Rio Hato
4.75 out of 5 average rating, 4 reviews

Charming & Quiet villa

karinaRating, 5 stars2 months ago
It is a beautiful villa, comfortable if you are looking to rest from the noise of the city and only want tranquility, super equipped, very beautiful. I would come back again without any hesitation
Superhost
Villa in Las Escobas del Venado
4.88 out of 5 average rating, 8 reviews

Villa Ceviche, Home at the Heart of Venao

GabrielRating, 5 stars3 months ago
We love Playa Venao and staying at Blue Venao makes the entire experience. We loved staying here and the decor touches that made it like a home. Yvonne was extremely responsive and made us feel welcome and at ease.
Villa in Las Escobas del Venado
4.86 out of 5 average rating, 7 reviews

Villa Oceana - Blue Venao 3BR

AntonRating, 5 stars1 month ago
Nice big place. Good location. Clean.
Guest favourite
Villa in Playa Venao
4.91 out of 5 average rating, 22 reviews

Best Located Villa in Blue | With Private Pool

DiogelRating, 5 stars3 months ago
Our experience at the house was exceptional, exceeding all our expectations. The location is unbeatable, and the property was extremely comfortable and perfect for our group. The private pool was undoubtedly the highlight of our stay, becoming the most captivating feature. Additionally, the proximity to the club and the beach added immeasurable value to the experience. Without a doubt, it would be a pleasure to return.
Villa in Saboga
4.66 out of 5 average rating, 38 reviews

Bahia Breeze 3 bdrm nature sanctuary with pool

MacRating, 5 stars3 months ago
This place is amazing and one that should be visited when you need that mental break or just time to escape. The house and pool are well kept and Juan Carlos who works for Robert was always available and very responsive. We appreciate Roberts quick and helpful response when we were unable to book the ferry to the island. The updates to the property and upkeep are what make it a jewel. I look forward to returning and spending more time in the future.
Villa in Bocas del Toro Province
4.94 out of 5 average rating, 63 reviews

Rare Luxury Villa & Casitas, Pool, Bocas del Toro.

ChrisRating, 5 stars3 months ago
A hidden gem! Surrounded by lush nature and close to the ocean, it offers cozy rooms and a peaceful atmosphere. The perfect place to relax and enjoy the beauty of the area. Scott and Debra were a pleasure to communicate with.
Villa in San José
4.62 out of 5 average rating, 13 reviews

Villa Futura by AcoModo

StephanieRating, 5 stars1 week ago
I had a wonderful experience at Acomodo's house. The team was a very organised and attentive host, always willing to help us and make sure everything was perfect. The house is even more beautiful in person and the atmosphere far exceeds what is shown in the photos. We had a great time making a delicious barbecue and the room was perfect for playing charades. The kitchen is nicely equipped and the beds are extremely comfortable. All the air conditioners worked perfectly. We hope to return soon!

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