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Mansion holiday rentals in Panama

Find and book unique mansions on Airbnb

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Top Guest favourite
Apartment in Maria Chiquita
5 out of 5 average rating, 25 reviews

Playa Escondida beachfront and lagoon

AnaRating, 5 stars1 week ago
Very comfortable and spacious apartment!! I loved the privacy of the rooms and the elegance of the double-height ceilings. The view from any of the windows is very beautiful. Carolina is a sweetheart, always communicative and very responsible. I will definitely return.
Guest favourite
Villa in Rio Hato
4.86 out of 5 average rating, 44 reviews

La Casa de las Uvas, an oasis with ocean views

LoriRating, 5 stars3 months ago
Wonderful stay. The pool, beautiful trees and well thought out outdoor seating was the perfect setting for our large family to vacation. Easy walk to the beach and restaurants. House had everything we needed. Mónica was very responsive to a very small issue we had and it was quickly remedied. Absolutely recommend.
Guest favourite
Cottage in Panama City
5 out of 5 average rating, 19 reviews

Hacienda La Perezosa in Cerro Azul

TeddyRating, 5 stars2 months ago
Very well maintained and clean. Perfect spot for a relaxing time with ample amenities and service staff. Will definitely repeat!
Superhost
Villa in Mariato
4.79 out of 5 average rating, 19 reviews

Villa Papagayo, Morrillo Beach, Veraguas

StacyRating, 5 stars2 weeks ago
Asta was a great host. Always responded promptly when we asked a question and was very proactive to make some recommendations immediately prior to the day we arrived. We had a few minor issues which were addressed promptly for the most part. The house was exactly as pictured and the location was great. Our group really liked the location and we would all stay there again.
Guest favourite
Boat in Río Azúcar
5 out of 5 average rating, 5 reviews

Private Luxury Catamaran

ChizzieRating, 5 stars2 months ago
Oh wow!! What a stay! We had 2 weeks around Costa Rica and Panama for our honeymoon and 3 nights were spent here, definitely the highlight! The boat is so beautifully kept and we were literally sailing in paradise. Anghie and Georgio were incredible and we were never left hungry or without a drink in our hands, be it beer, wine or a simple spirit and mixer. The food was fantastic, super fresh and they catered for allergies. The bed rooms were very comfortable and equipped with fans so even when the A/C turns off (in the middle of the night) you can still keep cool. Every day we were taken to (often) completely uninhabited islands where we could snorkel, paddle board or kayak but we would have been welcome to stay on the boat relaxing in the sun. It was the best way to spend time for our honeymoon, with privacy when we wanted it but also great, friendly company! We were lucky enough to book it for just the two of us but we are already planning our next trip - this time with friends!
Superhost
Home in Coronado
4.76 out of 5 average rating, 25 reviews

CHARMING HOUSE IN FRONT OF THE SEA WITH POOL-CROWNED

MathieuRating, 5 stars2 months ago
I really loved the Hamacas casa What a beautiful place You can’t go wrong being right on the beach Lots of restaurants near by Super safe to walk around Coronado Marcella was super helpful and answered Us every time we had a question The house was great mind you we didn’t really stay in the house other than going to bed Daniel the grounds keeper was super nice and helpful All and all I wouldn’t definitely rent this place again hopefully in a bear future
Top Guest favourite
Apartment in Panamá
5 out of 5 average rating, 38 reviews

Top Floor Condo 6 bedroom with amazing views

Nehal ManjibhaiRating, 5 stars2 weeks ago
Great location. Near Via Argentina so lots of restaurants, bars, life just a few steps away. Felt safe walking around and people were very friendly as well. Just a few blocks away from Constitution Ave which had a large grocery store, shopping, etc. Uber was $5 to Old Panama and other near by attractions. Worth it!
Top Guest favourite
Villa in Panamá
4.98 out of 5 average rating, 54 reviews

Breathtaking Views Mansion w/King Beds

MelissaRating, 5 stars6 days ago
The home is breathtaking and the host was so gracious. When we arrived, we were met by Dario who welcomed us and gave us a tour. There are four floors of amazing space and you feel like you are in a palace. We enjoyed the pool, media room, and billiard room and were surprised to see the mini-golf on the 4th floor. There are patios everywhere and the views are stunning. There are plenty of supplies for cooking and the dining room comfortably seats 8. We highly recommend this home, and we hope to return. Thank you Bradley and Dario for a fabulous experience!!

Pet-friendly mansion rentals

Superhost
Place to stay in Portobelo
4.86 out of 5 average rating, 22 reviews

Oceanfront Villa

AdrianaRating, 5 stars4 months ago
This place is perfect to enjoy a relaxing het away, having the beautiful ocean view and tropical breeze right outside of the house it is priceless! The pool and Jacuzzi are well maiy and make a great complement of the whole experience! The host thought about every detail to make the guests very welcome, by providing essentials for personal cleaning products, kitchen extra essentials and outdoors supplies. We really enjoyed the stay.!
Top Guest favourite
Villa in Costa Esmeralda
4.97 out of 5 average rating, 97 reviews

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.

AstridRating, 5 stars1 week ago
Excellent host, place and communication. We were accommodated easily and fast, the place was very comfortable and clean, amenities were more than expected.
Guest favourite
Condo in El Chirú
4.88 out of 5 average rating, 26 reviews

Laguna Fun and Sun: Your Escape Awaits

LauraRating, 5 stars3 weeks ago
Excellent accommodation, I would definitely go back there, our host Mark was excellent as always, always attentive to any information we required
Guest favourite
Villa in San José
4.84 out of 5 average rating, 74 reviews

25% OFF The Family Mini Resort House @Punta Barco

ElenaRating, 5 stars3 days ago
The house is beautiful and very spacious. We had a great time and would like to come back soon. Communication was also very good.
Superhost
Villa in El Valle de Antón
4.91 out of 5 average rating, 46 reviews

Quinta El Bosque

DanielRating, 5 stars3 months ago
Awesome place surrounded by nature. Beautiful views. Great place to disconnect and have some peaceful and chill time.
Superhost
Chalet in Juan Hombron
5 out of 5 average rating, 4 reviews

Charming house with beach access

GalinaRating, 5 stars3 months ago
Geraldina's house is beautiful and very comfortable, every detail has been taken care of with the utmost affection. The beach is one of the best in the area, suitable for bathing and strolling. But the best part is Geraldina, with her positive attitude, resolution and good energy, always ready to improve the experience and make you feel at home. We recommend this place 100%. We had a fantastic few days.
Superhost
Home in Gamboa
4.87 out of 5 average rating, 95 reviews

BirdHouse@ Gamboa Panamá Canal

FrancescaRating, 5 stars3 months ago
What an incredible stay we just had. This is our third time to Panama and our first in Gamboa and it was amazing. The home was gorgeous and spacious. The kid zone was a blast for both kids and adults. We went on a zip lining tour and the boat tour of the canal, monkey island and Embera tribe and they were worth every penny. Our 9-12 year olds felt safe and saw every animal on our wish list. Just an amazing adventure topped off by the privacy of our own home with a gorgeous pool. We just loved it. Thank you so much!!!
Guest favourite
Home in Rio Hato
5 out of 5 average rating, 35 reviews

Spectacular lake view villa in Decameron

Maria AntoniaRating, 5 stars1 month ago
Lovely place with comfortable outdoor areas and good beds! We had a great time :)

Mansion rentals with a pool

Guest favourite
Holiday home in San Carlos
4.92 out of 5 average rating, 48 reviews

Welcome to our house in Playa Corona

FranklinRating, 5 stars1 month ago
It is the perfect place to disconnect everything and at the same time everything minutes away. The house is as described and has an amazing view. There are fruit trees, palm trees, and beautiful summers that make it a heavenly place. I went with my wife and 5 adult children, they were all comfortable. The terrace is huge and the pool large. Full recommended
Guest favourite
Villa in Rio Hato
4.97 out of 5 average rating, 30 reviews

Villa Agueda Decameron, golf club and swimming pool

JeremyRating, 5 stars5 months ago
What a place, one of the better Air B &B’s in Panama, have everything you require, nice pool, cold jacuzzi that works, very amazing stay Annelise, thanks for everything.
Home in Playa Venao
4.89 out of 5 average rating, 130 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

BethRating, 5 stars1 month ago
We had an incredible stay at Casa Azul! The location is perfect with a beautiful pool and the beach right out the door. It’s walkable to the main restaurants and stores, but quiet and private that you can really relax. The house really helped all of us relax and enjoy our time in Venao. Thank you! Will definitely be coming back again!
Guest favourite
Home in Panama City
4.95 out of 5 average rating, 40 reviews

Nice duplex house with a swimming pool.

MaricelRating, 5 stars1 week ago
Don Gerardo was an amazing host. He picked my family and I up from the airport and welcomed us to his place with a cake which he did not need to do at all. He went above and beyond by offering us advice on local spots and attractions and completely changing the washing machine when the last one had issues. He was very attentive and welcoming to my elderly parents. He even drove my daughter back home from the airport after dropping her off there (one hour round trip) as she had forgotten something important at his place. The house was huge and exactly what my family and I needed. There were no issues at all from the house apart from the aforementioned washing machine which he rectified immediately when we were out of the house. Would definitely recommend to anyone with a big family to stay in Gerardo’s place. He is just an amazing guy and super super host . Highly recommended
Superhost
Home in PA
4.8 out of 5 average rating, 95 reviews

Villa GiGi - Beach Home Panama Santa Clara

EmilyRating, 5 stars3 months ago
Lovely home very close to the beach. There was so much to do at the house we didn't spend much time at the beach! The pool was great, we thoroughly enjoyed our time here.
Guest favourite
Condo in El Chirú
4.96 out of 5 average rating, 28 reviews

Buenaventura | Luxury Beach Apartment | Panama

RenataRating, 5 stars1 month ago
Our stay in Rapha's apt was spectacular. The apartment is super comfortable to be with a family, it is very well equipped and very clean. They also have details that make you feel at home, like a baby chair, plates, glasses, etc. We loved the place, the apartment and the attention we received from Rapha! We will definitely come back and recommend it 100%.
Guest favourite
Apartment in Panamá
4.95 out of 5 average rating, 42 reviews

140 m2 apartment down town Panama-City

Corinna Rating, 5 stars3 weeks ago
Very cool neighborhood, friendly people everywhere from the front desk to anywhere we walked. The pool is just right and the kitchen had everything we needed. AC was a delight after the warm humid days, would stay again. Gerhard was super to deal with and very friendly and helpful
Top Guest favourite
Home in San Carlos
4.96 out of 5 average rating, 25 reviews

House in El Higo, San Carlos.

JuanRating, 5 stars3 months ago
We had an excellent experience on our stay. The house is spacious, comfortable and everything was in order upon our arrival. We had a little inconvenience with the stove, but Mr. Christian was very attentive and quickly sent someone to help us. We really appreciate the quick response and attention to detail. We would definitely recommend this place and return in the future. Thank you!

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