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Villa holiday rentals in Panama City

Find and book unique villas on Airbnb

Top-rated villa rentals in Panama City

Guests agree: These villas are highly rated for location, cleanliness and more.

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Superhost
Villa in Coronado
4.85 out of 5 average rating, 40 reviews

Beachfront Sanctuary: Nature, Serenity, And Peace

Modern beachfront house with direct ocean access, fire pit & BBQ area. 3 bedrooms for 6-8 guests, master suite with private ocean-view balcony. Gourmet kitchen with stunning onyx stone counters, therapeutic Kohler showers, organic garden. 3 parking spaces in secure gated community with 24/7 security, Olympic pool, kids pool, tennis court, playgrounds. Walk to famous Luna Rossa Italian restaurant, Picasso bar & local shops. Your private beachfront paradise where every weekend feels like vacation!

Superhost
A welcoming private villa is surrounded by tall trees, showcasing a spacious layout. A swimming pool and trampoline are visible in the backyard, and the exterior features large windows allowing natural light. A green pathway leads to the entrance, emphasizing the serene, forested environment.
Villa in Panamá
4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Guest favourite
A tranquil beachfront scene features several hammocks strung between palm trees on soft sand. Blue lounge chairs are positioned alongside the water, with gentle waves lapping at the shore under a clear sky.
Villa in Chame District
4.86 out of 5 average rating, 233 reviews

Surf Relax Play Pacific Ocean View Villa

White sand, surf-able waves, or just a comfortable chill vibe to enjoy the tropical weather of Panama. Playa Caracol is about an hour and 10 minutes drive from the city. This spacious, 2 bedroom, 2 bath villa with it's Pacific Ocean front location is the perfect place for you to enjoy an unforgettable family vacation. Walk out to the beach just steps from the villa, swim in the pool next to this villa or enjoy the resort pools and amenities. Or hike the nearby mountains with a local guide. PET

Guest favourite
A spacious swimming pool is framed by lounge chairs, with a bright pink float positioned in the water. The villa's exterior is visible in the background, showcasing a large parking area and covered terrace with a red roof, surrounded by greenery.
Villa in Portobelo
4.92 out of 5 average rating, 25 reviews

Villa con piscina, cancha de fútbol y arroyo

Tranquila y espaciosa villa en Portobelo, Buenaventura. Disfrute de una villa con un gigante jardín, rio, cancha de fútbol, piscina con cascada y tobogán , 2 bohíos, áreas de barbacoa, terraza. 1 recámara principal con cama king y baño privado. 2 recamaras con 2 camas full. 1 baño en la sala. 1 baño en el área de la piscina y ducha externa. Sala, Comedor. Televisor por cable. Cocina equipada. Hamacas. * la casa está equipada con camas para 10 personas, llevar colchones inflables con sábanas.

Top Guest favourite
A modern outdoor area features a turquoise swimming pool surrounded by lush greenery. The space includes a partially covered patio with seating options and an outdoor bar area. Tall buildings are visible in the background against a clear blue sky.
Villa in Santa Cruz De Chinina
5 out of 5 average rating, 27 reviews

5BR House in Panama City w/ Pool & King Beds

Enjoy a family or friends' getaway in this modern, newly remodeled house. This property boasts 5 bedrooms, 4.5 bathrooms, 10 beds, and can comfortably accommodate up to 15 guests. The house also features a private outdoor pool, where you can soak up the sun and cool off on hot days, all while being in a central location, just meters away from malls, supermarkets and night life. It's fully furnished with everything you could possibly need to ensure your stay is as comfortable as possible.

Guest favourite
Large sliding glass doors open to reveal a view of the serene garden and swimming pool, complemented by lush greenery. A cozy corner with a comfortable sofa and decorative plants adds to the relaxed indoor ambiance.
Villa in Panamá
4.86 out of 5 average rating, 147 reviews

Bonita casa con piscina a pasos de la playa

Relájate con toda la familia en muestro Rincón de Flavio, un lugar tranquilo para quedarse el fin de semana o tanto tiempo como necesites. Tres recamaras con dos baños. Plenamente equipada y decorada con estilo tropical. AHORA SI QUE TENEMOS AIRE ACONDICIONADO EN TODOS LOS CUARTOS. Con todo lo que necesitas para disfrutar y relajarte. A 5 minutos caminando de la playa de Coronado y cerca de restaurantes y supermercados. Amplio Jardín, ping pong, piscina y cómodo patio con barbacoa.

Guest favourite
An outdoor dining area is shown with a glass-top table surrounded by six woven chairs. A view of the beach and ocean is visible in the background, framed by tall palm trees under a clear sky.
Villa in Chame
4.84 out of 5 average rating, 108 reviews

Ocean front Villa (C5-1C) 2 bed, 2 bath

Unique Villa steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space with sofa bed (6 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. Playa Caracol is located on the beach of Chame and is a newly developed area with expansion for the property and amenities. 1km of beach to offer you the best beach experience around.

Top Guest favourite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
5 out of 5 average rating, 74 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top Guest favourite
The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.
Villa in Santa Cruz De Chinina
4.97 out of 5 average rating, 133 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Guest favourite
A bright living area features a neutral-colored sofa adorned with a decorative throw. A round coffee table occupies the center, while a television is mounted on a wooden accent wall. A dining table with black chairs is visible in the background, along with an open kitchen.
Villa in Chame District
4.97 out of 5 average rating, 32 reviews

​Villa Playa Caracol, 3 Bedrooms, Pet Friendly

¡Welcome to your perfect beach getaway! This charming ground-floor villa awaits you just 100 meters from the golden sand and refreshing waves of the sea. This home offers an ideal retreat for families and groups of friends looking to relax and enjoy the sun and sea breeze. Enjoy the pool right in front of the villa, where you'll also find a playground for everyone to enjoy. ¡Book now and experience a dreamy seaside vacation!

Top Guest favourite
A cozy bedroom features a spacious bed with a patterned coverlet, complemented by a bedside table and a lamp. A wardrobe is positioned nearby, and curtain panels frame the window, allowing natural light to filter in. The minimalist decor creates a serene atmosphere.
Villa in Panamá
5 out of 5 average rating, 13 reviews

Villa Helena Studio 1 Apt Cerro Azul

One bedroom cottage with private kitchen and bathroom in a peaceful compound with shared pool. Internet and free parking available. Laundry facilities available for longer stays. Cook your own meals, or have me cook some authentic Caribbean dishes like curries, or use the restaurant available next door. Surrounded by nature and access to trails, waterfalls, rivers, swimming holes.

Top Guest favourite
Aerial view of a secluded beach where golden sand meets clear turquoise waters. Lush greenery surrounds the shore, with palm trees dotting the landscape. Rocky formations are visible at the water's edge, enhancing the natural beauty of the tranquil setting.
Villa in Saboga
5 out of 5 average rating, 19 reviews

Saboga: El Remanso Beachfront Entire Upper Level

El Remanso is our oasis, only 28 steps from the beach. This rental unit comprises our entire upper level, with 2 bedroom suites, each with ensuite baths. There is a small kitchenette between the two suites that is included for the exclusive use of guests. Each suite has a deck overlooking the beach below.

Popular amenities for Panama City villa rentals

Quick stats about villa rentals in Panama City

  • Total holiday rentals

    Explore 10 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $123 AUD per night before taxes and fees

  • Verified guest reviews

    Over 340 verified reviews to help you choose

  • Family-friendly holiday rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 10 rentals that welcome pets

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore

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