Guesthouse holiday rentals in Panama City

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Top-rated Guesthouses in Panama City

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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A small private pool is surrounded by lush greenery, creating a serene atmosphere. Large glass doors lead into the interior space, framed by decorative vases on either side. The pool area features a textured concrete deck, enhancing the connection with the tropical environment.

Guesthouse in Panamá

4.8 out of 5 average rating, 85 reviews

Cool Guesthouse+WiFi+Pool+Tv+AC @Canal de Panama

✔️SuperAnfitrion Verificado! Tu estadía estará en las mejores manos Casa de huespedes, Cerca al Ciudad del Saber 🇵🇦 📍 En el bosque tropical de la antigua base de Clayton, con comodidades, parques, deportes y gastronomía. Cerca de la ciudad, centros comerciales, las Esclusas de Miraflores y el ferrocarril transoceánico🇵🇦 Ofrecemos: 💧 Agua Caliente 📶 Wifi ❄️ AC 🏊‍♂️ Piscina 📺 Tv Smart y Cable 🚗Parqueadero Esta localización estratégica, con un alto nivel de seguridad en el área.

Guest favourite

The image captures a tranquil sunset above the ocean, with the sun casting golden reflections on the water. A small, dark table and two chairs sit beside a salt-water pool, surrounded by tropical foliage, creating a serene and peaceful setting.

Guesthouse in Veracruz

4.94 out of 5 average rating, 18 reviews

2 chambres dans jardin tropical

Dormir au calme entouré de végétation luxuriante à 20 minutes de panama logement spacieux adapté à 2 couple ou famille de 4 personnes 1 lit Queen et 2 twins avec chacun salle de bains privée attenante , mise à disposition d’un lit parapluie Salle de repos hamac , salle de repas cuisine équipée, une piscine eau salée pour vous divertir face à l’océan dont vous êtes les seuls utilisateurs entourés d’un grand jardin Espace de travail avec Wifi rapide Sports nautiques, randonnées à proximité

A cozy studio area features a spacious bed with a striped blanket. A small round table with two chairs is situated near a window adorned with dark curtains. A television stands on a dresser, and a door leads to a closet space. An air conditioning unit is mounted on the wall.

Guesthouse in Panamá

4.79 out of 5 average rating, 19 reviews

Anexo privado tipo estudio cerca de Costa del Este

Pequeño anexo muy lindo y acogedor tipo estudio (todo en una sola área) muy acogedor súper agradable, limpio. Anexo adyacente a nuestra casa, privado e independiente con todas las comodidades dentro de él para su estancia , con aire acondicionado split, smart tv, wifi,Amplio baño ducha con agua caliente , cocina con todos sus electrodomésticos, área para estacionar un auto. Ubicado en un área residencial muy tranquila, muy buena zona. Excelente ubicación. A pocos minutos de Costa del Este.

A modern living area features a stylish grey sofa adorned with colorful cushions, providing comfort and visual interest. A wooden bookshelf with various decorative items and books is positioned nearby. Soft lighting emanates from a cluster of candles on a round table, creating a soothing atmosphere.

Guesthouse in El Cangrejo

4.75 out of 5 average rating, 20 reviews

Rare City Oasis with Private Green Space

No more construction. Wake up to the sound of birds in this peaceful retreat in the heart of trendy "El Cangrejo". Housed on the ground-floor apartment of a 2-story building built in the 50's. Features a private green yard — perfect for relaxing or spotting hummingbirds. There is an outdoor dining set. Steps from cafés, galleries, parks, metro, and nightlife, yet quiet and tucked away. Only one neighbor on site. Private parking. Thoughtfully decorated with pieces from local artisans.

The bungalow is nestled among lush greenery, with tall trees and vibrant plants surrounding its entrance. A private parking space is visible in front, and the structure features a light-colored exterior with a welcoming porch. The clear blue sky adds to the serene atmosphere.

Guesthouse in Panama City

4.74 out of 5 average rating, 84 reviews

Efficiency Bungalow - Metropolitan Natural Park

Casita Curundu is located in a quiet and beautiful neighborhood next to the Metropolitan Natural Park. A naturalist delight right in the city, surrounded by an urban jungle forest teeming with birds and wildlife. An amazing place for a couple to stay - you’ll have all the privacy you need but still be close to all the great attractions and the large shopping and transportation hub Albrook Mall, Airport, Bus & Metro Station and yet removed from the hustle and bustle of the city.

A modern living space is outlined with light colors and simple furnishings. A wall-mounted TV is positioned above a low cabinet, while a cozy sofa bed is accompanied by a decorative pillow. Large sliding glass doors invite natural light and provide views of the outdoor patio area.

Guesthouse in Panamá

Trendy Tiny Apartment in Ancon

Nestled in the former Canal Zone, this cozy apartment offers comfort, nature, and city access. Near the City of Knowledge, The Panama Canal and Albrook, it’s perfect for exploring history and culture. We proudly welcome LGBTQ+ travelers and allies to a safe, inclusive space where you can relax and feel at home. Whether you're a solo traveler, a couple, or a digital nomad, you’ll find a warm, affirming environment here. Enjoy tropical hikes, city views, and local events. 🌈

Superhost

A cozy sleeping area features a spacious bed with neutral-toned bedding, complemented by a textured throw. A small workspace with a table and chair is positioned nearby. A wardrobe provides storage, and light enters through a window with simple coverings. Air conditioning unit is mounted on the wall.

Guesthouse in Panamá

4.71 out of 5 average rating, 7 reviews

The Black Studio by SS • near airport & city

This unique PRIVATE place has a style all its own. This stylish place is anything but ordinary. It is affordable and its perfect for a couple or business trips. Conveniently located next to shopping malls and supermarkets you’re literally 3 minutes from the train station and just 20 minutes to the city. Don Bosco is a safe place. Enjoy a cozy place with everything you can need for your stay. This place is private with its private entrance. IT IS NOT SHARED!

Top Guest favourite

Guesthouse in Panamá

4.76 out of 5 average rating, 246 reviews

Garden Cottage in Panama City

Welcome to our charming cottage, an oasis in the heart of the city, ideal for nature lovers and comfort seekers. Located in a central area, this retreat offers the perfect combination of tranquility, comfort, and proximity to Panama's main attractions. Enjoy the balance between urban life and the serenity of the natural surroundings. It features a private entrance, a spacious garden, a barbecue area, and a terrace where you can relax and connect with nature.

Guest favourite

A cozy sleeping area features a wooden bed dressed in a floral-patterned quilt and decorative pillows. Soft lighting is provided by bedside lamps, while light filters through a window adorned with sheer curtains, enhancing the calming atmosphere of the room.

Guesthouse in Gamboa

4.88 out of 5 average rating, 72 reviews

Casa de huésped privada en Ancón

Disfruta de la sencillez de este acogedor alojamiento tranquilo y céntrico. Cerca de lugares de interés como el edificio de la Administración del Canal de Panamá, Amador Causeway, Albrook Mall, y varios restaurantes. Personalmente decorado para proporcionar comodidad... grandes ventanales en el dormitorio proporcionan iluminación natural y una vista del jardín y el área verde a través de las ventanas; aun así mantiene la privacidad y la tranquilidad deseada.

Superhost

The kitchen features modern appliances, including a stainless steel gas stove and a white refrigerator. A compact sink is positioned beneath a small window, while kitchen essentials are arranged along a shelf above. Counter space is available for meal preparation, complemented by subtle wall tiles.

Guesthouse in Panamá

4.5 out of 5 average rating, 16 reviews

Conveniente Suite céntrica y con estacionamiento

This special place is close to everything, making it easy to plan your visit. 5-10 minutes to any attraction in Panama City. Assigned parking and two blocks from major bus stop that can take you anywhere in the city or accross the country. You will have the entire place for yourself with independent entry, air conditioning and kitchen. There are four grocery stores walking distance. You can exercise daily at a park located behind the property.

Guest favourite

A small seating area is visible outside the entrance, featuring two black metal chairs positioned on tiled flooring. Nearby, a plant is displayed on a low table, while decorative plants add a green touch to the surrounding space. A large window lets in natural light.

Guesthouse in Panamá

4.93 out of 5 average rating, 42 reviews

CASA PINO, bosque en la ciudad

Excelente Aparta-estudio independiente con todo lo necesario, Baño Privado, Cocineta Nevera y WIFI. Con mucha seguridad. Pueden utilizar máquinas en el parque para hacer ejercicios. Estamos ubicados en un área privilegiada en las revieras del Canal, con mucha vegetación y bosques, pero muy cerca de todas las amenidades recreativas de la Ciudad del Saber. Muy céntrico, a 10 minutos en metro-bus hasta Albrook Mall, a 10 minutos del Canal de Panamá.

Guest favourite

A well-lit bedroom features a spacious bed dressed in a light quilt. Two bedside tables with lamps sit on either side. Blue decorative pillows add a pop of color against the neutral walls, while an air conditioning unit and a vibrant artwork piece enhance the atmosphere.

Guesthouse in Distrito San Miguelito, Brisas del Golf, Panama City

5 out of 5 average rating, 27 reviews

Apartamento en área residencial segura

Estarás cerca de todo cuando te quedes en este alojamiento céntrico. Alrededor de 20 minutos del aeropuerto de Tocumen, 15minutos de Estadio Romel, de paso para Zona Libre Colón cerca de comercios, restaurantes, farmacias, supermercados, cines, facilidad de transporte. Si el viaje es de trabajo, de turista, o en tránsito por Panamá en este apartamento podrás estar con comodidad. Estamos a su disposición si requiere información adicional.

Popular amenities for Panama City guesthouses

Kitchen

Wi-Fi

Pool

Free parking on premises

Air conditioning

Family-Friendly guesthouses

Private room in Panamá

New place to stay

Espectacular habitación doble para 4 personas

A private room features two beds, an overhead ceiling fan, and a large window with shades. A TV is mounted on the wall, while a desk is positioned nearby. The room is complemented by neutral wall tones and a decorative accent pillow on one bed.

Private room in Panamá

Comfort & Privacy room 8/Panamá

A sleeping area features a spacious bed adorned with a patterned blue and white duvet. The walls display abstract geometric designs in shades of blue and grey. Soft lighting enhances the creative atmosphere with details captured from the unique wall art.

Private room in Obarrio

Private Ensuite Room

A bright and spacious private room contains two beds arranged with neutral bedding. A small desk is positioned near a wall-mounted TV. Natural light enters through multiple windows equipped with blinds, and a fan hangs from the ceiling, contributing to the room's comfort.

Private room in Panamá

Cozy room7/ GuesthousePanamá

Shared room in Panamá

New place to stay

ExpC7 Social Vibes • Budget Stay • Easy Check-in

A cozy room features a spacious bed with a white quilt. Natural light enters through large windows, and a ceiling fan adds comfort. A wooden wardrobe and a bedside table are present, enhancing the room's functionality. A wall-mounted television is also situated in the space.

Private room in Panamá

Private Room 1, Bella Vista/Panamá

A bright room is highlighted by large arched windows, allowing natural light to fill the space. A small wooden desk is positioned beside a mirror, with a gentle breeze suggested by the visible greenery outside. The walls are painted in blue and white, enhancing the airy ambiance.

Private room in Obarrio

Private Room in Smart Hostel

Private room in Panamá

New place to stay

Espectacular habitación para 4 personas, dos camas

Guesthouses with a patio

An aerial view captures a single-story wooden room with an orange roof, surrounded by lush greenery. The mist envelops the area, creating a serene backdrop. Pathways are visible leading through the garden, enhancing the connection with the natural environment.

Private room in Panamá

4.8 out of 5 average rating, 15 reviews

Luxury Ecolodge

A spacious retreat is outlined amidst a forest setting, featuring a wide deck and large windows that invite nature inside. Brightly colored steps lead up to the entrance, surrounded by greenery and natural elements, creating a serene atmosphere.

Guesthouse in Panamá

Casa del Rio Cerro Azul Panama

Guest favourite

A comfortable sleeping area features a spacious bed adorned with floral-patterned bedding. A bedside table holds a lamp, and a vase with fresh flowers adds a touch of color. Large windows allow natural light, creating a bright and airy atmosphere.

Private room in Panama City

4.95 out of 5 average rating, 40 reviews

Alojamiento cercano a Tocumen AirPort

Private room in Gamboa

Room+Parking+TV+Kitchen+Work Area+WiFi@PanamáCity

A spacious room features a large bed with crisp white bedding. A bedside lamp provides soft lighting next to a white side table. A desk is positioned against the wall, paired with a chair. A compact refrigerator is situated in one corner, and a TV is mounted on the wall.

Private room in Panamá

Private Room 5/guesthouse Panamá

Private room in Panama City

New place to stay

Habitación entrada independiente con baño privado.

A cozy bedroom features a bright yellow wall that complements floral bedding on a spacious bed. A large television is mounted on the wall opposite the bed, while a small table is tucked beside it. Air conditioning is present for comfort.

Private room in Panamá

Habitación privada con baño

Superhost

Private room in Panamá

New place to stay

Hab amplía con precio tipo hostal

Guest house rentals with a washing machine and dryer

A clear blue pool is surrounded by a concrete patio, offering a refreshing space for relaxation. Lush green grass borders the area, and a building with multiple windows is visible in the background. A swing set stands nearby, contributing to a family-friendly environment.

Guesthouse in San Miguelito

Mi casa

An outdoor area features a dining table surrounded by several chairs, set on a tiled surface. Potted plants with vibrant flowers are present, and a large umbrella provides shade. Air conditioning units are mounted on the exterior wall, adding comfort to the space.

DONDE YOYI

Smart Stay by SS • Budget Studio 3+ Airport & Mall

A bright bedroom features a spacious bed with light-colored bedding. Two nightstands with lamps flank the bed, providing soft illumination. A small table holds a decorative vase with flowers. Natural light enters through a window covered by sheer curtains, enhancing the room's calm ambiance.

Private room in Gamboa

4.64 out of 5 average rating, 11 reviews

Room, nature, sauna and eveything, near the sea.

Superhost

Guesthouse in Panamá

New place to stay

Smart Stay by SS • Budget Studio 5+ Airport & Mall

A single-story building is depicted, featuring arched windows framed in red. The exterior is painted in light and dark tones, with a motorcycle parked nearby. Overhead power lines are visible, and the surrounding area includes a textured pavement.

Guesthouse in Panama City

Alquila habitacion amoblado san antonio

A clear view of a sparkling pool stretches towards the horizon, where the ocean meets the sky. The water reflects the blue tones of the atmosphere, while fluffy clouds drift above, creating a serene coastal scene.

Private room in Marbella

Ocean front Apartment by San Francisco, PTY

Guest favourite

The exterior of a spacious villa is framed by lush greenery and colorful flowers. Palm trees and shrubs are positioned around the entrance, which is marked by a low wall. A paved driveway leads to a garage, providing easy access.

Private room in Panama City

4.86 out of 5 average rating, 7 reviews

Suite in Mountain Villa

Quick stats about guesthouse rentals in Panama City

Total holiday rentals
Explore 80 holiday rentals in Panama City
Nightly prices starting at
Panama City holiday rentals start at $15 AUD per night before taxes and fees
Verified guest reviews
Over 1,490 verified reviews to help you choose
Family-friendly holiday rentals
10 properties offer extra space and kid-friendly amenities
Pet-friendly accommodation
Find 20 rentals that welcome pets
Holiday rentals with a pool
10 properties feature pools
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Wi-Fi availability
70 of Panama City holiday rentals include Wi-Fi access
Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals
Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)