
House holiday rentals in Panama City
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Quick stats about house rentals in Panama City

Total holiday rentals
Explore 480 holiday rentals in Panama City

Verified guest reviews
Over 8,400 verified reviews to help you choose

Family-friendly holiday rentals
200 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 160 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
240 properties have a dedicated workspace

Wi-Fi availability
440 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated house rentals in Panama City
Guests agree: These houses are highly rated for location, cleanliness and more.

Welcome to Zola Sierra! Your Escape Into Nature.
Welcome to Zola Sierra. Your Private Escape Into the Heart of Nature. Step into the serenity of Zola Sierra, a one-of-a-kind 3-bedroom, 3-bath sanctuary nestled deep within the protected highlands of Cerro Azul, Panama. Designed for dreamers, seekers, and soul-restorers, this home is more than a stay — it’s a nature-immersive experience that effortlessly blends modern luxury with untamed wilderness. Come for the views. Stay for the stillness. Fall in love with the wild magic of Zola Sierra!

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Amplia Residencia Privada en Excelente Zona
Casa en las mejores zona del país. Calle muy tranquila, céntrico, cerca de Restaurantes, Farmacias, Mall entre otros. Amplia Residencia cómoda para grupos o Familias. Estacionamiento Privado de hasta 2 autos 4 Recamaras espaciosas , 2 cómodos estudios, Sala Comedor, Desayunador, Amplia Terraza. *Opcion Kosher Disponible* House in one of the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall and more. Large comfortable residence for groups.

Family-Friendly Panama Canal Home with Fenced Yard
Welcome to our 3-bedroom vacation rental in Cardenas, Panama Canal area! Perfect for families, this home boasts a kitchen with quality appliances, including a 6-burner gas stove and a large fridge. Relax in stylish bedrooms, featuring a king suite with a private bath, and enjoy the lush surroundings filled with wildlife. Located next to a park with sports courts, this kid-friendly neighborhood offers outdoor fun. Experience the unique blend of comfort and nature right at your doorstep!

Naturaleza maravillosa
Disfruta de un retiro familiar en plena naturaleza, donde la tranquilidad te envuelve. Este acogedor alojamiento, rodeado de un hermoso jardín en el Parque Natural Metropolitano, te ofrece un escape único a solo 3 minutos del Albrook Mall y 5 minutos del centro. Despierta con el canto de las aves y la visita de ñeques, mientras te relajas en un ambiente exclusivo y lleno de vida. ¡La escapada perfecta para desconectar y disfrutar de la naturaleza con todas las comodidades!

Cómodo y lujoso apartamento
Disfruta de una experiencia con estilo en nuestro alojamiento en el Casco Antiguo, aprovecha la ubicación cercana a galerías de arte, restaurantes, artesanías,etc. Nuestra casa cuenta con tres habitaciones cada una con balcón, baño y closet, con una bonita cocina contemporánea equipada; una amplia sala y comedor , zona de labores. Cuentas con un area total de 326 mts² Toda la casa rodeada de balcónes donde puedes disfrutar de las vistas panorámicas.

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Estudio Privado a 10 Min del Aeropuerto !
Apartamento Entero a 10 MINUTOS del Aeropuerto! El apartamento está completamente amueblado incluyendo electrodomésticos y artículos de cocina , productos de aseo , sala comedor ,mesa de trabajo y demás. A sólo minutos caminando de la Estacion de METRO SAN ANTONIO y METROMALL. Ofrecemos Tours a San Blas -Tours a Monkey Island y el Canal de Panamá para que aproveches al maximo tu viaje. Nuestra casa es Tu casa en Panamá 🇵🇦

3BR Mountain Retreat | Starlink WiFi | Cerro Azul
Escape to the cool mountain weather of Cerro Azul and enjoy a modern home surrounded by nature. Perfect for families, groups of friends, and remote work, with high-speed Starlink internet for seamless video calls and streaming. Relax on the spacious balcony, enjoy the BBQ gazebo, and unwind from city life while surrounded by fresh air, peaceful surroundings, and natural views. Have questions? Send us a message today!

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.
Popular amenities for Panama City house rentals
House rentals with a pool

Majestuosa Villa en Las Montañas

Casa de las cascadas

La Casa de la Cascada tiene bbq, pin pon, gym

Oceanfront views/access w/ Pool, Privacy & Space

Home On The Lake Cerro Azul

Tu casa de campo, Menus de la Montaña, te espera.

La Fontana Scape

Villa la Vista - majestic mountain hideaway
Weekly house rentals

Ambiente Acogedor y Seguro Cerca del Aeropuerto

casa-ac-wifi6-parking-familiar-rentacar

Moderna casa con A/C & WiFi · cerca Panama Canal

Loft de diseño con terraza privada

A little House in Panama City

Designer Canal Home - Med or Longterm

Charming House in Casco Viejo

Cozy cabin in nature with garden in Cerro Azul
Private house rentals

6A Golden Space | Design By Paradox

Tiny House in the Nature by HYTTE HOMES

Swiss-Designed Cozy Home w/ Stunning Rooftop

La Cabaña de Lu, refugio en la montaña.

Panama Canal Heritage House

Unique 4 room house - direct access to the beach

Cantabria House - 10 minutes from the Airport

Forest View Cabin | Wi-Fi | BBQ | Cerro Azul
Destinations to explore
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- Rentals with beach access Panama City
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- Things to do Panama
- Food and drink Panama
- Art and culture Panama
- Nature and outdoors Panama
- Sightseeing Panama
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