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Holiday houses in Panama City

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Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Apartment in Obarrio
4.96 out of 5 average rating, 27 reviews

Modern apartment in the heart of Obarrio

This apartment stands out for its prime location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The comfort of having two bathrooms makes it unique. Ideal for travelers looking for tranquility and functionality. Located within walking distance of Calle 50 and the iconic El Tornillo building. You're surrounded by casinos, hotels, and restaurants. Safe area to walk and enjoy the city.

Top Guest favourite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Apartment in Panama City
5 out of 5 average rating, 88 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Guest favourite
A rooftop area features a refreshing pool surrounded by sleek decking, with city views in the background. Comfortable lounge chairs are positioned alongside the pool, inviting relaxation. The modern architecture is complemented by large windows that enhance the overall openness of the space.
Apartment in Marbella
4.83 out of 5 average rating, 18 reviews

Exclusivo Apto/Av Balboa/Pool/Gym/AC/View/Parking

Vive una experiencia única frente al mar en este lujoso y amplio apartamento, disfrutarás de una piscina con vista directa al océano, perfecta para relajarte. El apartamento está completamente equipado para una estancia inolvidable. Además, el edificio ofrece amenidades premium como sauna, gimnasio, billar pool, parqueadero y una espectacular terraza con vista 360° de la ciudad. Situado en una zona céntrica, estarás a pasos de los mejores restaurantes, tiendas y atracciones locales.

Top Guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Apartment in Santa Ana
5 out of 5 average rating, 57 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Top Guest favourite
A stylish living area features a modern white TV unit mounted on the wall, with decorative elements and a cozy seating option. A queen bed is visible in the adjacent space, complemented by warm wooden paneling. Natural light fills the room through large windows.
Apartment in Panamá
5 out of 5 average rating, 23 reviews

Remote Working • Rooftop Pool Gym • NearMultiplaza

➤ Nice apartment with balcony, nestled conveniently near Multiplaza Mall . ★ Perfect for Remote Workers, desk with chair to work, 750 MB internet speed, 100 Up. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Entertainment. ➤ Urban Escape - Building Highlights: ★ State-of-the-art Gym ★ 2 Co-Working Spaces, 500 MB speed internet. ★ Chlorine-free Pool on the Rooftop Terrace. ➤ Located in Central San Francisco: Explore the City Easily | Uber-Friendly

Top Guest favourite
Apartment in Panama City
4.97 out of 5 average rating, 95 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Top Guest favourite
Apartment in Panamá
5 out of 5 average rating, 11 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Top Guest favourite
The spacious living area is highlighted by decorative tiles on the floor and large windows adorned with intricate woodwork. A comfortable seating arrangement includes a light blue sofa and dark armchair, while a wooden dining table with four chairs occupies the center. An entertainment unit is visible against the stone wall.
Loft in Panama City
5 out of 5 average rating, 12 reviews

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
Apartment in Panamá
5 out of 5 average rating, 4 reviews

Cozy Studio in Cinta Costera with Home Vibes

✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Guest favourite
Apartment in Panamá
4.99 out of 5 average rating, 135 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A modern living area is illuminated by a stylish light fixture. A comfortable white sofa is paired with a round coffee table and accentuated by decorative cushions. Large glass doors provide a view of the city skyline, while a wooden accent wall adds warmth to the space.
Apartment in Panamá
4.94 out of 5 average rating, 85 reviews

New Apartment in Panama City

Explore Panama City with style from our luxurious 1-bedroom apartment in San Francisco. The apartment is brand new and designed specifically for your comfort. Ideal for 2 guests, with a private bedroom, fully equipped kitchen, and a balcony with city views. Building amenities include a pool, gym, co-working center, and 24-hour security. Near shopping, dining, and Parque Omar. Book your stay today!

Superhost
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Apartment in Panama City
4.89 out of 5 average rating, 161 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Popular amenities for Panama City holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Panama City?

    Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.

  • What are the best things to do in Panama City with kids?

    Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.

  • What are some of the best things to do in Panama City?

    Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.

  • How is the weather in Panama City?

    Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.

  • What are the best places to visit in Panama City?

    Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.

  • What are some hiking trails in Panama City?

    Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.

  • What are some family activities we can do in Panama City?

    Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.

  • What are some of the best day trip ideas from Panama City?

    Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.

  • Are there any pet friendly accommodations available in Panama City?

    Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.

  • What are some local tips for visiting Panama City?

    When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.

  • What is Panama City known for?

    Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.

  • What are the best hidden gems to explore in Panama City?

    Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.

  • What are the best foods to try in Panama City?

    Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.

  • What should I bring for a trip to Panama City?

    Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.

  • What is the nightlife in Panama City like?

    Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.

  • What are the most popular events or festivals in Panama City?

    Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.

  • Are there family friendly vacation rentals in Panama City?

    Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.

  • When is the best time to visit Panama City?

    The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.

Quick stats about holiday rentals in Panama City

  • Total holiday rentals

    Explore 4,860 holiday rentals in Panama City

  • Verified guest reviews

    Over 124,900 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,530 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 1,800 rentals that welcome pets

  • Holiday rentals with a pool

    2,660 properties feature pools

  • Rentals with dedicated workspaces

    2,930 properties have a dedicated workspace

  • Wi-Fi availability

    4,620 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill and Laptop-friendly workspace across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore

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