Pet-friendly holiday rentals in Santee

Find and book unique pet-friendly homes on Airbnb

Quick stats about holiday rentals that are pet-friendly in Santee

  • Nightly prices starting at

    Santee holiday rentals start at $427 AUD per night before taxes and fees

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santee rentals

  • 5 Average rating

    Santee stays are highly rated by guests—averaging 5 out of 5!

Top-rated pet-friendly home rentals in Santee

Guests agree: These pet-friendly homes are highly rated for location, cleanliness and more.

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Top Guest favourite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 223 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favourite
A serene lakeside view captures a wooden dock extending into calm waters, surrounded by trees. Buildings are visible in the background, subtly illuminated by dusk light. The sky displays gentle hues of blue and pink, reflecting the tranquil atmosphere of the location.
Home in Vance
4.97 out of 5 average rating, 37 reviews

Lakefront w/ dock at Mill Creek

Nestled between Santee & Eutawville, Vance is less than an hour from Downtown Charleston. Experience lake life w/ a front row seat to live music, dancing & karaoke at the Mill Creek Marina! Float over to grab a bite or drink at the Barefoot Lakeside Bar & Mill Creek Food & Spirits! Community hosts golf cart parades, Halloween bash, & a spectacular 4th of July fireworks show. Launch your pontoon a few doors down, tie up at your dock & conveniently fuel up at the marina. Campground store on site!

Top Guest favourite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 269 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Superhost
Cabin in Saint Matthews
4.77 out of 5 average rating, 199 reviews

A relaxing cabin on private pond. Old Bells Secret

Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

Guest favourite
A relaxing private patio is furnished with two chairs and a small table, offering views of Lake Marion. The serene surroundings include lush trees and a clear water edge. A rug adds a cozy touch, while a pet is seen lounging nearby, enhancing the inviting atmosphere.
Condo in Santee
4.9 out of 5 average rating, 41 reviews

Lake Life Living-W/Boat waterfront condo

Nestled in a cozy cove along the shores of Lake Marion, this pet friendly retreat offers an escape for anglers, boaters, and golfers seeking both tranquility and convenience. This 2-bed, 2-bath condo is conveniently located off I95, making it an excellent base for exploring nearby areas. Lake Marion ranks among the largest lakes in the US offering world-class fishing. Santee also provides an exceptional golfing challenge making this a premier vacation destination for the golf enthusiasts.

Top Guest favourite
Home in Manning
4.96 out of 5 average rating, 24 reviews

Lakefront Retreat | Dock, Firepit & Pet Friendly

Wake up to panoramic Lake Marion views, fish from your private dock, relax around the waterfront firepit, and enjoy a peaceful lakefront getaway just steps from the water. Enjoy peaceful mornings, sunset evenings, and easy access to fishing, boating, swimming, and lake life. Pet Friendly: Well-behaved pets are welcome! Please keep pets off furniture and clean up after them inside and outside the property. Multiple pets may be considered case-by-case—please message us before booking.

Top Guest favourite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.81 out of 5 average rating, 105 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favourite
Home in Summerton
4.94 out of 5 average rating, 185 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Top Guest favourite
A cozy front porch is depicted, featuring two blue chairs under a covered roof. The white exterior walls and large windows create an inviting space. Lush greenery and neatly arranged landscaping surround the area, enhancing the peaceful outdoor setting.
Barn in Gaston
4.95 out of 5 average rating, 185 reviews

Congaree Vines - Barn Bungalow by a Vineyard!

-Enjoy a quiet country stay, complimentary port wine from our vineyard, and a fire-pit under the stars! This charming Barn Bungalow is wonderfully situated next to our hobby vineyard and lovely meadow walk! -Congaree Vines also has a Woodland Cottage! Pets welcome for a fee! If service dog, provide paperwork. -We are near Congaree National Park (33 min), Columbia, USC, Ft. Jackson, Airport, I-26 & Hwy77. -15% off guided kayaking w/Carolina Outdoor Adventures.

Guest favourite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.96 out of 5 average rating, 199 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top Guest favourite
Home in Summerton
4.97 out of 5 average rating, 37 reviews

Almost Heaven on Lake Marion, SC

Enjoy a serene getaway at our lake front spacious 3-bedroom, 2-bathroom lake house. Features include a king-size master bedroom with en-suite bathroom, queen and two full-size beds in other rooms, fully equipped kitchen, winter-only fireplace, screened porch with ample seating, smart TVs in all rooms, high-speed Wi-Fi, gas BBQ, private sandy beach, covered dock with power and seating, boat ramp, and ample parking. Dog-friendly (no cats). location provided after booking.

Top Guest favourite
Home in Summerton
4.98 out of 5 average rating, 42 reviews

Sunset Serenity Pool/Swim Spa

Experience next-level lakefront luxury in this brand-new 5BR/3BA custom home featuring a massive open-concept layout, chef’s kitchen, two master suites, and resort-style amenities like 20x40 infinity pool, swim spa, and fire pit. Enjoy a private dock, multiple lounge spaces, dual laundry sets, paddleboard/kayaks, and designer finishes throughout. Every detail of Sunset Serenity was designed for comfort, beauty, and unforgettable moments on Lake Marion.

Popular amenities for Santee pet-friendly home rentals