
Family-friendly holiday rentals in Santee
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in Santee

Total holiday rentals
Explore 30 holiday rentals in Santee

Nightly prices starting at
Santee holiday rentals start at $143 AUD per night before taxes and fees

Verified guest reviews
Over 180 verified reviews to help you choose

Holiday rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
30 of Santee holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santee rentals

4.8 Average rating
Santee stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Santee
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Lovely Condo w/pool, balcony, and lakeside view!
Relax on the balcony overlooking the pool and lake Marion or go down and relax at the pool, or launch your boat at the boat ramp for the day and go fishing or cruising. There is also a myriad of golf courses near by. For dinner with a great view head over to the other side of the lake to the Lake House bar and grill for adult beverages on the lake with great food. For upscale dining Clark’s restaurant is a good choice. Bike,hike,or cook out over at Santee state park which is only 10 minutes away

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Relaxing Comfortable Waterfront Family Dock Suite
Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Perfect Family Retreat at Lake Marion
Great water front family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. We purchased our home is 2006 and began a complete interior and exterior renovation. In 2023 we installed solar panels and an electric vehicle charging station, yet we also have access to the grid for cloudy days and when power demand exceeds what our panels generate. We use a deep well for water. Bring your family for an off-the-grid vacation in our lake home!

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

A Great Lake house. Near Manning, SC and I-95.
Secluded and serene, our private lakefront property in South Carolina's Lake Marion region offers a community feel with minimal traffic and noise. The fenced-in property has 2 cozy bedrooms, a large open floor plan, and a screen porch with a beautiful lake view. Enjoy the private dock, kayaks, and floats, and relax with a bonfire and grill. Conveniently located just 20 minutes from Manning and I-95, our retreat is perfect for travelers looking to unwind and recharge.

Cheerful 3 bedroom home on the lake
Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Congaree Vines - Woodland Cottage by a Vineyard!
-Enjoy a Quiet Country Stay! This charming European style cottage is set by a Hobby Vineyard! Enjoy complimentary port wine from our vineyard, a fire pit and hammock under the stars! -Congaree Vines also has the Barn Bungalow. Pets are welcome for a fee. If service dog, bring paperwork. -We are near Congaree National Park (33 min), Columbia, USC, Ft. Jackson, Airport I-26 & Hwy 77. -15% off Guided Kayak in CNP w/Carolina Outdoor Adventures.

Reelaxation-At Lake Marion
Unplug and enjoy the laid back charm of this cozy 2BR cabin near Lake Marion. Located in a gated community, it features a private boat ramp, boat parking, and plenty of space to relax and grill after a day of fishing on the lake or golfing at one of local golf courses. Enjoy peaceful mornings, family and friend time, and quiet evenings on the porch. Perfect for anglers, golfers, and family getaways.

Lake Marion | Chill, Cruise, or Cast a Line for 8!
Wake up to quiet mornings, sip coffee by the water, cast a line, and let the day slow down. This Lake Marion home is all about relaxing, fishing, and unplugging with your favorite people. This is the perfect place to reset, recharge, and enjoy the simple things. No rush. No noise. Just lake life, done right.
Popular amenities for Santee family-friendly rentals
Family-friendly home rentals with a hot tub

Sunset Serenity Pool/Swim Spa

Luxury Farm Stay | Hot Tub, Pool & Animals

KING, 4 beds, 5 minutes to I-26

Lake Moultrie retreat

Lakeview Leisure-Face to the Sun

Pickleball/Basketball Court - Movie Room - Hot Tub

The Canopy | Glamping Tent

Ultimate Lake Marion Dream Home W/Pool & Swim Spa
Family- and pet-friendly home rentals

Lakefront home with boat ramp and game room

Lakefront w/ dock at Mill Creek

Almost Heaven on Lake Marion, SC

Fish Haven I

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Lake Life Living-W/Boat waterfront condo

Lakefront Lookout

Lakefront Retreat | Dock, Firepit & Pet Friendly
Family-friendly home rentals with a pool

Spacious Retreat Near Charleston, Pet Friendly

Charleston area private pool 3 BR home!

Hearts & Dreams Peaceful Family Retreat w/ pool

Lakefront Farmhouse Retreat+Pool

Wyboo Retreat at Lake Marion W/Pool

Lake Marion "Penthouse" at Club Wyndham Resort

Quiet Retreat:Secluded & Idyllic

Lake and pool side vacationing
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- Family-friendly rentals Orangeburg County
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- Congaree National Park
- Riverbanks Zoo and Garden
- North Charleston Coliseum & Performing Arts Center
- University of South Carolina
- Magnolia Plantation & Gardens
- Middleton Place
- Williams Brice Stadium
- South Carolina State House
- South Carolina State Museum
- Cypress Gardens
- Charleston Southern University
- Columbia Museum of Art
- Colonial Life Arena
- West Columbia Riverwalk Park and Amphitheater
- Sesquicentennial State Park
- Columbia Metropolitan Convention Center
- Wannamaker County Park
- Edventure
- Riverfront Park
- Soda City Market
- Whirlin' Waters Adventure Waterpark
- Koger Center for the Arts
- Segra Park
- Azalea Park





