Holiday houses in Santee

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Top-rated holiday rentals in Santee

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Guest favourite
A view from the balcony captures a serene landscape featuring a pool adjacent to Lake Marion. Lush greenery and palm trees frame the scene, while guests enjoy the pool area. The tranquil waters of the lake are visible in the background under a clear sky.
Condo in Santee
4.96 out of 5 average rating, 93 reviews

Lovely Condo w/pool, balcony, and lakeside view!

Relax on the balcony overlooking the pool and lake Marion or go down and relax at the pool, or launch your boat at the boat ramp for the day and go fishing or cruising. There is also a myriad of golf courses near by. For dinner with a great view head over to the other side of the lake to the Lake House bar and grill for adult beverages on the lake with great food. For upscale dining Clark’s restaurant is a good choice. Bike,hike,or cook out over at Santee state park which is only 10 minutes away

Guest favourite
Home in Vance
4.88 out of 5 average rating, 8 reviews

Lake House Getaway

Relax with the whole family at this peaceful place to stay at the lake. Cozy 3 bedroom, 1.5 bath lake house set on top of a hill to create beautiful views. Located near golfing community of Santee in the small town of Vance, SC. Quiet area with a private dock on deep water. An outdoor shower was recently added. Water mat, 2 single inflatable kayaks, 1 single inflatable kayak and floats available to enjoy. TVs with Roku streaming are available for all your streaming accounts. WiFi available.

Top Guest favourite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 233 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Top Guest favourite
A spacious lakefront home is visible from the water, surrounded by lush green trees. The two-story structure features porches on each level. A sandy beach area and grassy yard lead up to the house, with white lounge chairs placed nearby, inviting relaxation by the water.
Home in Summerton
4.96 out of 5 average rating, 48 reviews

Large Lakefront Home w/360 view, beaches, & dock

This family-friendly spacious lakefront home with dock is located on a peninsula and boasts water access on three sides of the property. Park your boat at your own personal dock using the boat ramp located directly across from the property. This property has room for 13 people, but there is also access to an air mattress. Enjoy the 3 huge porches, fire pit, paddle boat, hammocks and swings, fishing, drop in your kayak or paddle board straight off the property and head out to Lake Marion.

Guest favourite
Home in Summerton
4.94 out of 5 average rating, 170 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Guest favourite
A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.
Home in Santee
4.96 out of 5 average rating, 170 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Top Guest favourite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 173 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top Guest favourite
Home in Santee
4.93 out of 5 average rating, 14 reviews

Sunny Santee Stay · 5BR Cityview · Lake & Golf

Brand new 2025 modern, cozy home near interstate I95, golf courses, markets, local restaurants (Cracker Barrel Old Country Store, Starbucks, etc) and Lake Marion. Santee is right in the middle distance between Miami and New York. Clean and stylish space with two 75” smart TVs, Wi-Fi, full amenities, and easy self check-in. Relax with the whole family at this new clean, quiet, safe and peaceful neighborhood. View our profile to explore more homes in the area.

Top Guest favourite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 126 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Guest favourite
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Apartment in Santee
4.91 out of 5 average rating, 32 reviews

Relaxation is the plan

Come and relax in this peaceful retreat. A beautiful view of the lake and the sunset from the comfort of the living area or outside on the spacious balcony, a stunning lakefront property offering breathtaking views. This meticulously maintained 2-bedroom, 2-bathroom condo is centrally located off I-95, providing both privacy and convenience. The serene lake views and well-kept interiors create a peaceful retreat for relaxation.

Guest favourite
Home in Summerton
4.95 out of 5 average rating, 19 reviews

Lakeside Dreams W/Pool & Spa

Welcome to Lakeside Dreams! This beautifully renovated 3BR/2BA lakefront home on stunning Lake Marion features a private pool, hot tub, private boat launch, pool table, and ping-pong. Enjoy modern style, comfort, and endless fun indoors and out. Perfect for family getaways, fishing trips, or relaxing by the water!

Guest favourite
A comfortable seating area is highlighted by a light grey sofa adorned with a patterned throw. Two vintage chairs frame a small coffee table, which is topped with books. Natural light filters through an arched window with a softly shaded blind.
Apartment in Elloree
4.89 out of 5 average rating, 18 reviews

Modern apartment overlooking a Historic Downtown

Relax at this peaceful and centrally-located getaway in the heart of historic Elloree, SC. Just minutes away from Santee, I95, I26, fishing and golfing, it's perfect for a quiet weekend getaway, business trip or staycation! Free electric car charging available for your convenience upon request.

Popular amenities for Santee holiday rentals

When is the best time to visit Santee?

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Frequently Asked Questions

  • Are there vacation rentals with a dedicated workspace in Santee?

    Yes! Work meets play with ease at over 10 vacation rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there Santee vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 20 vacation homes with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!

  • How much does it cost to stay in apartment rentals in Santee?

    Experience the best of Santee with our apartment rentals, starting at about $150 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Do apartment rentals in Santee have wifi?

    Absolutely! We offer over 10 apartment rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Santee have a gym?

    Absolutely! We offer over 10 apartment rentals with a gym in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Are there family-friendly vacation rentals in Santee?

    Santee has more than 30 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

Quick stats about holiday rentals in Santee

  • Total holiday rentals

    Explore 30 holiday rentals in Santee

  • Nightly prices starting at

    Santee holiday rentals start at $142 AUD per night before taxes and fees

  • Verified guest reviews

    Over 220 verified reviews to help you choose

  • Family-friendly holiday rentals

    30 properties offer extra space and kid-friendly amenities

  • Holiday rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    30 of Santee holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Self check-in, Gym and BBQ grill across Santee rentals

  • 4.8 Average rating

    Santee stays are highly rated by guests—averaging 4.8 out of 5!