Guesthouse holiday rentals in Santa Clarita

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Santa Clarita

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Guest favourite

Guesthouse in Malibu

4.94 out of 5 average rating, 177 reviews

Two Goat farm in Malibu Mountains, Cozy & Charming

Rustic canyon getaway in clean-air, rural Malibu mountains! Private gravel entrance w parking. Adjacent to incredible canyon & ocean views, singing birds, hiking. Quiet neighborhood for heavenly sleeps. One queen bed, One trundle bed with two single mattresses, one air mattress. A/C for summer, space heater for winter. Kitchenette (no kitchen sink) and full bath. Highlights! Claw-foot Tub Mountain Sunsets Amazon Echo Wild Bird families & bunnies Hiking at end of road 2.5 miles to the beach

Guest favourite

Guesthouse in Canyon Country

4.87 out of 5 average rating, 199 reviews

HILLSIDE GETAWAY next to Magic Mountain

Great reviews beautiful quiet neighborhood on top of hill with an amazing view of the surrounding mountains w/private entrance 15min drive to six flags magic mountain bike paths an nature trails shopping and malls less than 5 min drive everything newly built all guests have given me 5star accommodations easily sleeps 4 people fold out couch in living room queen size bed in bedroom room 16 ft high cathedral ceiling private balcony /tables&chairs purfect to unwind 30 min from universal studios

Guest favourite

Guesthouse in Sylmar

4.98 out of 5 average rating, 188 reviews

Tranquil Studio w/ private patio

A beautiful and well maintained Tranquil Studio/ With a Private Patio. Entire Studio to yourselves. 2 guests. 1 queen bed..1 queen/futon couch, with lovely bed linens and plush towels. 1 tub/shower.Futon made up on request at the time of booking. Full kitchen with everything you’d need to make delicious meals. 55” TV/ DVDs Washer/dryer...please bring your own laundry soap and dryer sheets. The gorgeous private patio has plenty of space to relax and enjoy your meals, or just hang out.

Superhost

Guesthouse in Topanga

4.9 out of 5 average rating, 101 reviews

Outdoor Clawfoot, Hot Tub, Deck - The Farmhouse

Welcome to the Farmhouse, a cozy studio retreat nestled in the Topanga hills. This inviting space features a comfy queen canopy bed, en-suite bath, and a kitchenette for light meals. The room opens onto a private deck and patio, perfect for waking up with the singing birds, and an outdoor clawfoot tub for a relaxing soak under the trees. Enjoy easy access to local attractions including cafes and restaurants, village shops, hiking trails with breathtaking views, and Malibu beaches.l

Guest favourite

Guesthouse in Chatsworth

4.91 out of 5 average rating, 218 reviews

Comfortable Private Studio - near hiking

Come get away to a slower pace at our thoughtfully appointed studio in the beautiful hills of Lake Manor! When staying at our place you will be a short drive to West Hills, Canoga Park, Calabasas, Northridge, and more. We are in a quiet neighborhood in the "country." Our studio setup allows traveling workers and getaway seekers to find the work-life balance they need with: ✧Comfy work desk ✧ High-speed Wi-Fi ✧Close by fun hiking trails ✧Roku TV ✧Shared outdoor space ✧ parking - free

Guest favourite

Guesthouse in Newhall

4.98 out of 5 average rating, 455 reviews

Cozy Guesthouse w pool, firepit & heated jacuzzi

GUESTHOUSE W PRIVATE USE OF BBQ, POOL, SLIDE, FIRE PIT & HEATED SPA CLEANED TO CDC RECOMMENDATIONS COMPLETELY SEPARATE FROM MAIN HOUSE WITH FENCE NO LOUD PARTIES, NO LIVE MUSIC. For your safety AIRBNB is not allowing parties or events to be hosted. NO MORE THAN 10 PEOPLE ALLOWED AT ANY TIME. Contact us if you need an exception. Guesthouse w kitchenette (no oven) living room, master bedroom, open loft (as 2nd bedroom) Dedicated parking, TV, WIFI, washer/dryer and private entrance.

Guest favourite

Guesthouse in Altadena

5 out of 5 average rating, 112 reviews

Light and Airy Canyon Retreat with Private Patio

This beautiful, recently remodeled guesthouse is nestled in the foothills of Altadena. We are in a lovely neighborhood in a quiet canyon. Stylishly decorated for your peace and comfort. Enjoy your coffee or a glass of wine outside in the enclosed private patio. Cozy yet spacious with high wood ceiling and lots of storage. Fully appointed modern kitchen and pretty bathroom. This home is truly special. A perfect retreat for artists, writers, business travelers, even a local getaway.

Guest favourite

Guesthouse in Northridge

4.97 out of 5 average rating, 278 reviews

Backyard paradise near CSUN, Universal & 6 Flags

Smell the flowers, pomelo blossoms and macadamia trees outside your window. The neighborhood and backyard allows for quiet sleep and star gazing by the pool (Puffy brand queen mattress). Porter Ranch is close to the 118 & 405. Non-rush hour driving in minutes: 5 ~ CSUN 20 ~ Burbank Airport (30 LAX) 20 ~ Universal Studios 20 ~ Six Flags/Hurricane Harbor 20 ~ Getty Center 30 ~ Downtown LA/Dodger Stadium 45 ~ Disneyland 60 ~ Santa Barbara 3.5-4 hours Las Vegas

Guest favourite

Guesthouse in Burbank

4.97 out of 5 average rating, 156 reviews

Private Guest Quarters with Patio & Bathroom

Enjoy a stylish experience at this centrally-located place in Burbank. Walking distance to Starbucks, minutes away from Disney Studios, Warner Bros. and Universal Studios. Conveniently located near the Hollywood Burbank Airport. Perfect for one-guest. Host lives on premises. Room has a private entrance with outdoor patio. There are two cameras located on the property, one on the Hosts front door, the second one attached to the Hosts home overlooking the backYard.

Guest favourite

Guesthouse in Burbank

4.99 out of 5 average rating, 157 reviews

Remanso GuestHouse-BurbankFoothills

Remanso is newly built two story guest house. It sits in the back of our gated property. Comfy, serene, clean and airy space situated in the foothills, the most desirable part of Burbank. Downtown Burbank is only a 10-12 minute walk, we are close to Hollywood Bowl, Universal Studios, Griffith Park; Downtown Los Angeles is about 14 miles away. Air conditioner, fast wifi. Washer and dryer on premises, gated carport. Private entrance, full kitchen.

Guest favourite

Guesthouse in Claremont

5 out of 5 average rating, 172 reviews

Claremont Studio 5 mins to Colleges | Non-Smokers

Our private Cedar Nest is a detached modern garden studio that sits at the rear of our lot in the foothills area of Claremont. We are close to hiking, about a 5 minute drive from the Village and Claremont Colleges (Pitzer College, Pomona College, Scripps College, Claremont McKenna College, and Harvey Mudd College). Easy access to the 210 freeway and a nice place to unwind after a day exploring Claremont and surrounding areas.

Guest favourite

Guesthouse in Santa Clarita

4.99 out of 5 average rating, 164 reviews

The Pines- a peaceful ranch guesthouse

Enjoy a rural getaway at this recently renovated guest house on a small ranch. Minutes from the 5 freeway, shopping, restaurants and conveniences, yet a world away in a quiet neighborhood with farm animals and open views. This is a great place for nature lovers, with lots of plants, birds and even seasonal frogs. We have an EV charger available. Please ask for details.