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Guesthouse holiday rentals in Santa Cruz Island

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Santa Cruz Island

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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The eco-chalet features a wooden staircase leading to a spacious front porch, framed by lush greenery. Large windows allow natural light to fill the interior, while the serene ocean views can be glimpsed in the background, enhancing the connection with nature.
Guesthouse in Puerto Ayora- playa de los alemanes
4.82 out of 5 average rating, 56 reviews

Galapagos - Santa Cruz Island - Janine's Chalet

Lose yourself inside the magic of nature offered by our mesmerizing Divines’ Bay Ocean-front Eco-chalets. For those looking to disconnect from busy city life, your waterfront chalet will give you the perfect backdrop of the majestic untouched wildlife of the Galapagos. While enjoying a cool drink, blue haroons and iguanas will become a part of your scenery to make your experience feel like a utopia. For those seeking adventure, swimming and snorkeling are available literally at your doorstep.

A spacious sleeping area features a neatly made bed covered with a white blanket topped with an orange runner. Two orange pillows rest against a padded headboard. Natural light floods in through a large window, with city views visible outside. A small lamp and a vase of flowers are placed beside the bed.
Private room in Puerto Ayora
4.21 out of 5 average rating, 14 reviews

Hostal Carliza I

Nuestro Alojamiento esta ubicado en la zona céntrica de Santa Cruz , muy transitada de turistas y cerca de nuestra avenida gastronómica “ La Calle de los Kioskos” , donde podrás ir deleitar la diversidad de nuestras islas. El espacio Cada habitacion cuenta con agua caliente, tv cable, disponibilidad de wifi solo en recepcion, utilizamos jabon y shampoo biodegradable para poder ser mas amigables con el medio ambiente :) Será un gusto Atenderte !

A spacious room is equipped with modern furnishings, including a comfortable sofa and accent chair. A stylish bed with decorative headboard is positioned opposite a large window, dressed with dark curtains. Clear signage detailing house rules is displayed prominently.
Private room in Puerto Ayora

COZY PLACE IN PUERTO AYORA

Relax with the whole family in this quiet place TO stay. This PLACE WILL BE your HOME a good place to have a good rest. Let's keep the directions so you can be informed. we are near the entrance to TurtleBay beach you can prepare your food everything you look for in a place so you can be with your family we will always be happy to tell you what you may need comfortable and modern facilities, the people who book can use the place

Guest favourite
An entrance is framed by lush greenery and flowering vines. The doorway leads into a space with light-colored walls and wooden elements, offering a view of the interior. Various plants surround the entrance, enhancing the natural ambiance.
Guesthouse in Puerto Ayora
4.88 out of 5 average rating, 72 reviews

Charles Darwin's Suite on the way to Tortuga Bay

¡Vive una experiencia auténtica en Galápagos! Alojamiento seguro, céntrico y eco-amigable, a solo 3 min de agencias, supermercados y la famosa Playa Tortuga Bay. ✨ Disfruta de: ✔ Cocina totalmente equipada ✔ WiFi rápido y estable ✔ Agua caliente con energía solar ✔ Espectacular jardín natural y zona de descanso 📌 Ubicación privilegiada + conexión con la naturaleza 💬 ¡Reserva ya! Escríbenos para más detalles. ¡Te esperamos!

Guest favourite
A private room features a wooden loft bed above a spacious bed, along with a small nightstand and a dresser. A step ladder provides access to the loft. Soft lighting illuminates the simple decor, creating a functional and restful environment.
Private room in Puerto Ayora
4.8 out of 5 average rating, 44 reviews

Rent - Room 2 - Twin & Bunk Bed - NO A/C

A simple place with the essential amenities for a quiet stay. Choose 1 or 2 beds Access the tourist spots quickly, just a 10-minute walk away: - Charles Darwin Station - Galapagos National Park - Beaches - Bars -Restaurants - Shops Just two blocks from the main avenue. CHECK-IN: 1:00 PM CHECK-OUT: 09:00 AM Contact us to receive information on arrival at the property. We always improve the room features.

Private room in Puerto Ayora

Family Room with Balcony

Discover Duncan Suites, the ideal place for your stay in Puerto Ayora. Just 5 blocks from Pelican Bay, enjoy a prime location near the esplanade, restaurants and shops. Unwind in spacious rooms with air conditioning, a fully-equipped kitchen, and fast Wi-Fi. Perfect for those looking for comfort, safety and easy access to the wonders of the Galapagos. Your unforgettable experience starts here.

A narrow pathway is flanked by white-walled buildings featuring brown wooden doors and large windows. Vibrant pink flowers and lush green plants enhance the natural setting. The clear blue sky overhead complements the tranquil atmosphere of the courtyard.
Guesthouse in Puerto Ayora

Guesthouse

* Enjoy the simplicity of this quiet and central accommodation in Puerto Ayora - Isla Santa Cruz, Ecuador. * Located on the main street a few steps from the main dock * We have tourist agency so you can enjoy a fabulous experience in the Galapagos Islands * Find excellent restaurants with exquisito dishes in our surroundings * Come and enjoy a comfortable place in our stay

A spacious bedroom features a large bed with a patterned coverlet, complemented by two bath towels neatly arranged on the side. Panoramic windows provide natural light and a view of the sea, framed by flowing blue curtains. A wooden dresser and a workspace with a chair are also present.
Private room in Puerto Ayora
4.5 out of 5 average rating, 133 reviews

Ocean Suite

. location with an excellent view to the sea of Puerto Ayora and easy access to bars and restaurants. . Ubicación con una vista a la costa de Puerto Ayora y fácil acceso a bares y restaurantes del lugar.

Top Guest favourite
A charming entrance features a wooden door framed by stone walls and surrounded by lush foliage. A winding staircase painted in calming blue leads up to the door, complemented by a decorative plant in a white pot at the base.
Guesthouse in Puerto Ayora
5 out of 5 average rating, 12 reviews

Cozy apartment

Forget your worries in this spacious and serene space, full of nature and amenities, in a quiet neighborhood of the Galapagos Islands, Santa Cruz.

A compact guest room features a spacious bed with a dark bedspread and a blue accent pillow. A wooden door leads to the room, while a closet with hangers provides storage space. A small desk and chair complete the setup, with overhead lighting illuminating the area.
Private room in Puerto Ayora
4.67 out of 5 average rating, 3 reviews

Accommodation Costa del Sol

Your family will be close to everything when you stay in this centrally located home.

A bright room features two beds and a comfortable chair, accompanied by a desk. Large windows with yellow curtains allow natural light to brighten the space. The orange floor complements the colorful plaid bed linens, creating a vibrant atmosphere.
Guesthouse in Santa Cruz

Valle del Amanecer Galapagos 2 Santa Cruz

We have banana fruit trees,oranges, seasonally an unforgettable place within nature.

Guesthouse in Puerto Ayora
New place to stay

Suite Standard

Desde este alojamiento céntrico todo el grupo podrá tener fácil acceso a todo.

Popular amenities for Santa Cruz Island guesthouses