
House holiday rentals in Santa Cruz Island
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz Island
Guests agree: These houses are highly rated for location, cleanliness and more.

Villa Náutica | Private Jacuzzi | Design
Perfect for couples, families or friends looking to relax in style in the Galapagos Villa Náutica is an elegant loft villa with a private jacuzzi, spacious areas and a unique nautical design inspired by my Swiss and Galapagos roots. Located in a quiet residential neighbourhood, it allows you to enjoy the tranquillity just a 12-minute walk from the centre of Puerto Ayora. It combines comfort, authenticity and the ideal environment to discover the islands and return to rest in a cosy retreat.
LocationFamilyQuiet

Shangri-La Legal Rental steps to the beach
Shangri-La is described as an imaginary remote paradise, secluded hideaway, a haven of beauty, tranquility, or as paradise on earth. Now you don't have to imagine Shangri-La, you can see it for yourself! Located in a secluded "auto-free" zone a short aqua taxi ride from Puerto Ayora. Footsteps away is Playa de Los Alemanes. Santa Cruz Island location makes for a perfect vacation making it easy to do day trips to nearby islands. Shangri-La is the perfect place for you to enjoy Galapagos.
ValueLocationQuiet

Great location, modern 4 guest house
Beautiful and legally registered property with great location, thoroughly decorated, comfortable for families or friends. Located 2 blocks away from Charles Darwin Ave. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, restaurants, cafés, shops, tour operators and more. Great option for guests seeking flexibility and comfort. All bedrooms have AC. Other areas benefit from cross ventilation and high ceilings keeping the house cool.
FamilyLocationNearby

Samana Stay
Samana Stay is a spacious two-level family home in a quiet walkable neighbourhood, with beaches and the Charles Darwin Research Station nearby. Designed for comfort and long stays, it offers generous living areas, air-conditioned downstairs bedrooms, reliable Wi-Fi, and a fully equipped kitchen. The open living and dining space opens to a private garden with cut lava-rock pathways, creating a calm outdoor retreat and complete “entire home” privacy, ideal for families and eco-travellers.
FamilyLocationComfort

Panata’s Paradise with Pool!
Space for everyone in this 3 bedroom, 4 bath home. Each bedroom has its own bathroom en-suite. Stay fresh with the pool and air conditioning, or kick back in the outdoor seating area around the pool. Kids can enjoy one movie in the play area upstairs while adults watch their own movie downstairs. Cook your own meals in the fully stocked kitchen and make use of the washer/dryer. This property is about a 25 minute walk from downtown or a quick $2 taxi ride.
FamilyLocationHospitality

Family Suite with Jacuzzi (included) photos 2026
Because we're one of the best Airbnbs.⚜️ Enjoy our Suite with your family or friends with tranquility, security, and modern and cozy comfort with everything included and quality service Enjoy our new Jacuzzi service ideal for all ages, parties, birthdays, etc. Enjoy a park in front of your stay (soccer, basketball, and children's games) Just a 3-4 minute drive to famous beaches, Las Grietas, La playa la Estación, Tortuga Bay.
ValueLocationSleep quality

Modern and Exclusive Accommodation
Galahouse is more than a house: a place to rest and live unforgettable moments with family, friends or a partner. It offers spacious rooms, an equipped kitchen, a cozy living room, a patio with hammocks, and a balcony with views. It has air conditioning, internet, TV and hot water. Close to the beach, shops and restaurants. Every corner invites you to relax and enjoy a comfortable vacation full of good energy.
LocationFamilyCleanliness

El Galapagueño House
Come! Enjoy the simplicity of this magical, quiet, centrally-located, and private place with your partner, family, or friends! An ideal place to rest after visiting the most extraordinary tourist sites of the Galapagos Islands!!! 🏡🐢🏞️🏝️☀️🐚 We look forward to seeing you! 15 minutes' walk to the pier 100 meters from the entrance to Tortuga Bay Beach 20 meters from the tennis court
FamilyLocationAir conditioning

Casita Muyuyo - Galapagos Islands!
This bright, fully licensed two-bedroom Airbnb is perfect for families or friends seeking a safe, private, and comfortable stay. Located in a walled garden complex near town and just steps from the entrance to the Tortuga Bay trail, it's a peaceful retreat after a day of exploring the Galapagos. Please note this is a fully legal airbnb, with a license from the Ministry of Tourism
ValueFamilyLaundry

Beautiful house with the best location in Santa Cruz
Relax with the whole family in this accommodation where tranquility is breathed. Located in one of the most exclusive and elegant neighborhoods of Puerto Ayora, just 200 meters away from the access to the Turtle Bay beach trail, very quiet and away from the noise of the shopping area. The house is close to the boardwalk and a few steps from restaurants and supermarkets.
LocationValueLong stay

Suite with AC + Kitchen looking for in East. Charles Darwin
Perfect for exploring the island on foot, just a 7-minute walk from the wharf and a few minutes from Charles Darwin Station. Perfect for stays of 3 to 7 nights Excellent choice for travellers looking for comfort and a good location. Fast Wi-Fi Easy access; located on the ground floor with a separate entrance.
ValueLocationGetting around

Gps Villa
Perfect Villa for family or group of friends. Located in the best neighborhood on the island, very close to the main pier, restaurants, supermarkets, souvenirs. You can enjoy our villa and its facilities. We have a heated Jacuzzi with hydrojets, patio, solarium, living room, dining room, and kitchen.
FamilyValueAir conditioning
Popular amenities for Santa Cruz Island house rentals
House rentals with a pool

Galapagos Cottages "Duplex Room"
ValueLocationBeach

Refugio Galápagos for 6 | Pool and balconies

Large house in a prime location
LocationHospitalityHeating

GALAPAGOS SHANGRI-LA 2 CASAS LEGAL&CLOSE TO BEACH
ValueFamilyNearby

GALAPAGOS COTTAGES "Family House"
ValueLocationKitchen
Weekly house rentals

Bucanero's Nest. Santa Cruz Galapagos
ValueLocationAir conditioning

Casa Lijera 1 holidays in the Galapagos
ValueLocationAccuracy

Spacious and bright house "Genovese family home"
ValueLocationTV

House in Puerto Ayora near the mall
ValueLocationHospitality

Vacation home in Galapagos, Santa Cruz
FamilyLocationAmenities

Anita's house
ValueLocationLaundry

Casa 3 Gecko
LocationFamilyShared spaces

Imagination Studio Home
Private house rentals

Modern and cozy house
LocationFamilyBathroom

CasaGalapagos Santa Cruz with Starlink Internet
ValueLocationComfort

Serene & Spacious Oasis with Terrace
LocationComfortCleanliness

Friends & Family Guest Home
ValueLocationWalkability

A spacious and comfortable place
FamilyComfortHospitality

Island Life Two Bedroom Galapagos Casita
ValueLocationAccuracy

House in Galapagos
LocationDecorCleanliness

Apartment for 4 people
LocationValueDecor
Destinations to explore
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