
House holiday rentals in Santa Cruz Island
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz Island
Guests agree: These houses are highly rated for location, cleanliness and more.

Villa Náutica | Private Jacuzzi | Design
Perfect for couples, families or friends looking to relax in style in the Galapagos Villa Náutica is an elegant loft villa with a private jacuzzi, spacious areas and a unique nautical design inspired by my Swiss and Galapagos roots. Located in a quiet residential neighbourhood, it allows you to enjoy the tranquillity just a 12-minute walk from the centre of Puerto Ayora. It combines comfort, authenticity and the ideal environment to discover the islands and return to rest in a cosy retreat.

Shangri-La Legal Rental steps to the beach
Shangri-La is described as an imaginary remote paradise, secluded hideaway, a haven of beauty, tranquility, or as paradise on earth. Now you don't have to imagine Shangri-La, you can see it for yourself! Located in a secluded "auto-free" zone a short aqua taxi ride from Puerto Ayora. Footsteps away is Playa de Los Alemanes. Santa Cruz Island location makes for a perfect vacation making it easy to do day trips to nearby islands. Shangri-La is the perfect place for you to enjoy Galapagos.

Great location, modern 4 guest house
Beautiful and legally registered property with great location, thoroughly decorated, comfortable for families or friends. Located 2 blocks away from Charles Darwin Ave. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, restaurants, cafés, shops, tour operators and more. Great option for guests seeking flexibility and comfort. All bedrooms have AC. Other areas benefit from cross ventilation and high ceilings keeping the house cool.

Samana Stay - 3BR
The home features two downstairs bedrooms with air-conditioning; A king size bedroom and a bedroom with two single beds. One large upstairs timber finished master bedroom with an en-suite and balcony located on the second floor. The open-plan living and dining area creates a bright, social space to gather after island adventures. Traditional Galápagos styling and craftsmanship runs throughout the home, with warm local timber and detailed woodwork.

Family Suite with Jacuzzi (included) photos 2026
Because we're one of the best Airbnbs.⚜️ Enjoy our Suite with your family or friends with tranquility, security, and modern and cozy comfort with everything included and quality service Enjoy our new Jacuzzi service ideal for all ages, parties, birthdays, etc. Enjoy a park in front of your stay (soccer, basketball, and children's games) Just a 3-4 minute drive to famous beaches, Las Grietas, La playa la Estación, Tortuga Bay.

Exclusive, Modern and Cosy Accommodation
What makes our place special is the perfect combination of comfort, cleanliness, and personalized attention that makes each guest feel at home. We have taken care of every detail to offer a cozy, quiet space equipped with everything necessary for an unforgettable stay. In addition, its excellent location allows you to easily enjoy the main attractions of the area, making it the ideal choice for both relaxing and exploring.

El Galapagueño House
Come! Enjoy the simplicity of this magical, quiet, centrally-located, and private place with your partner, family, or friends! An ideal place to rest after visiting the most extraordinary tourist sites of the Galapagos Islands!!! 🏡🐢🏞️🏝️☀️🐚 We look forward to seeing you! 15 minutes' walk to the pier 100 meters from the entrance to Tortuga Bay Beach 20 meters from the tennis court

Casa Tortuga - Spacious, Bright, and Private Home
Casa Tortuga is a fully licensed Airbnb offering a peaceful, private getaway in the Galapagos. This bright, spacious two-bedroom + 1.5 bathroom home is tucked inside a walled garden oasis with its own entrance, large terrace, and modern kitchen — perfect for couples, families, or friends. Please note this is a fully legal airbnb, operating with a license from the Ministry of Tourism

House in Puerto Ayora near the mall
Enjoy your vacation in Galapagos with the whole family or friends in this stylish accommodation. A small house with its own patio where you have a small laundry room in case your shoes got dirty on one of the tours, it also has a barbecue so you can enjoy an afternoon meal with seasonal seafood... the house and its outdoor area is totally private for your own use and your company.

Beautiful house with the best location in Santa Cruz
Relax with the whole family in this accommodation where tranquility is breathed. Located in one of the most exclusive and elegant neighborhoods of Puerto Ayora, just 200 meters away from the access to the Turtle Bay beach trail, very quiet and away from the noise of the shopping area. The house is close to the boardwalk and a few steps from restaurants and supermarkets.

Suite with AC + Kitchen looking for in East. Charles Darwin
Perfect for exploring the island on foot, just a 7-minute walk from the wharf and a few minutes from Charles Darwin Station. Perfect for stays of 3 to 7 nights Excellent choice for travellers looking for comfort and a good location. Fast Wi-Fi Easy access; located on the ground floor with a separate entrance.

Gps Villa
Perfect Villa for family or group of friends. Located in the best neighborhood on the island, very close to the main pier, restaurants, supermarkets, souvenirs. You can enjoy our villa and its facilities. We have a heated Jacuzzi with hydrojets, patio, solarium, living room, dining room, and kitchen.
Popular amenities for Santa Cruz Island house rentals
House rentals with a pool

Panata’s Paradise with Pool!

Galapagos Cottages "Duplex Room"

Refugio Galápagos for 6 | Pool and balconies

GALAPAGOS SHANGRI-LA 2 CASAS LEGAL&CLOSE TO BEACH

GALAPAGOS COTTAGES "Family House"
Weekly house rentals

Bucanero's Nest. Santa Cruz Galapagos

Spacious and bright house "Genovese family home"

Anita's house

Vacation home in Galapagos, Santa Cruz

Casa 3 Gecko

Imagination Studio Home

Vacation home

Modern and cozy house
Private house rentals

Friends & Family Guest Home

Serene & Spacious Oasis with Terrace

A spacious and comfortable place

Accommodation in Puerto Ayora

Island Life Two Bedroom Galapagos Casita

Family House near Charles Darwin Station

Apartment for 4 people

COSTA DEL SOL Galapagos Islands
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