House holiday rentals in Santa Cruz Island
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz Island
Guests agree: These houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz Island house rentals
House rentals with a pool
Home in Puerto Ayora, Santa Cruz Island, Galapagos Islands
4.52 out of 5 average rating, 21 reviews2 Bedroom House "The Galapagos Pearl Hotel"️
8 – 15 Oct
Home in Puerto Ayora
5.0 out of 5 average rating, 8 reviewsPanata’s Paradise with Pool!
8 – 15 Dec
Home in Santa Cruz
New place to stayOcean view
6 – 13 Jan
Home in Puerto Ayora
5.0 out of 5 average rating, 12 reviewsGALAPAGOS COTTAGES "Family Home"
11 – 18 Dec
Home in Puerto Ayora
4.89 out of 5 average rating, 9 reviewsGALAPAGOS SHANGRI-LA 2 CASAS LEGAL&CLOSE TO BEACH
6 – 13 Aug
Weekly house rentals
Home in Puerto Ayora, Isla Santa Cruz - Islas Galapagos
4.88 out of 5 average rating, 60 reviewsApartment for 4 people
2 – 9 Mar
Home in Puerto Ayora
4.84 out of 5 average rating, 63 reviewsScalecia - Private, comfortable and stylish house
12 – 19 Sept
Home in Santa Cruz
New place to stayVilla Peregrina
7 – 14 May
Home in Puerto Ayora
4.86 out of 5 average rating, 101 reviewsGreat Blue Heron Modern Apartment
25 Aug – 1 Sept
Home in Puerto Ayora
4.69 out of 5 average rating, 16 reviewsPelican suite II
1 – 8 June
Home in Puerto Ayora
5.0 out of 5 average rating, 12 reviewsSpacious Deluxe Villa with 3 Bedrooms & Lake Views
22 Feb – 1 Mar
Home in Puerto Ayora
4.52 out of 5 average rating, 63 reviewsBaysuites casa
20 – 27 Aug
Home in Puerto Ayora
4.85 out of 5 average rating, 27 reviewsEden house
20 – 27 Apr
Private house rentals
Home in Puerto Ayora
New place to stayFriends & Family Guest Home
27 Jan – 3 Feb
Home in Santa Cruz
New place to stayVilla Bonita Luxury Residence
31 July – 7 Aug
Home in Puerto Ayora
New place to staycasa bonita, near the sea
13 – 20 Nov
Home in Puerto Ayora
Make yourself at home Gala House
5 – 12 Sept
Home in Puerto Ayora
Domicile for holidays
11 – 18 Feb
Home in Puerto Ayora
New place to stayCasa Familiar Vacacional
31 Aug – 7 Sept
Home in Bellavista/Santa Cruz
Entire home Galapagos, Puerto Ayora Ecuador
10 – 17 June
Home in Puerto Ayora
New place to stayTurtle-Commodic Room
11 – 18 Nov
Destinations to explore
- San Cristobal Holiday rentals
- Isabela Island Accommodation & holiday rentals
- Puerto Ayora Accommodation & holiday rentals
- Santa Cruz Accommodation & holiday rentals
- Baltra Island Holiday rentals
- Puerto Villamil Holiday rentals
- San Cristóbal Island Holiday rentals
- Puerto Baquerizo Moreno Holiday rentals
- Playa de Oro Holiday rentals
- El cascajo Holiday rentals
- Playa los alemanes Accommodation & holiday rentals
- Point Carola Beach Holiday rentals
- Earth house rentals Ecuador
- Tiny house rentals Ecuador
- Townhouse rentals Ecuador
- Guesthouse rentals Ecuador
- House rentals Ecuador
- Guesthouse rentals Galápagos Islands
- House rentals Galápagos Islands
- Guesthouse rentals Galápagos Islands
- House rentals Galápagos Islands
- Waterfront rentals Santa Cruz Island
- Smoking-friendly rentals Santa Cruz Island
- Rentals with a fireplace Santa Cruz Island
- Apartment rentals Santa Cruz Island
- Serviced apartment rentals Santa Cruz Island
- Rentals with outdoor seating Santa Cruz Island
- Kid-friendly rentals Santa Cruz Island
- Rentals with pools Santa Cruz Island
- Rentals with a fire pit Santa Cruz Island
- Pet-friendly rentals Santa Cruz Island
- Monthly Rentals Santa Cruz Island
- Rentals with beach access Santa Cruz Island
- Hostel rentals Santa Cruz Island
- Bed and breakfasts Santa Cruz Island
- Rentals with breakfast Santa Cruz Island
- Hotel rentals Santa Cruz Island
- Rentals with a hot tub Santa Cruz Island
- Rentals with a washing machine and dryer Santa Cruz Island
- Rentals with a patio Santa Cruz Island
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom