House holiday rentals in Rochester

A cozy living area is featured, highlighting a brick fireplace with a warm glow. A marble countertop is positioned in the foreground, accompanied by two glasses of red wine and a plate of assorted fruit garnished with a purple flower. Natural light accentuates the scene.

4.92 out of 5 average rating, 195 reviews

The BEST Stay in Town: See Pics+Reviews to Believe

One level living/no stair. 2 bedrooms with 3 beds One-side of a duplex home: 1,200 Squarefeet w/ your own private entry, parking, laundry, kitchen.. 2.5 miles to Mayo, Target, Hyvee, gas stations...Fully furnished home. Smart TV & Fridge w/ Superfast internet & NetFlix included. Easy self-check-in keypad. A few blocks to the bus stop. Modern/spacious interior. Fully equipped kitchen w/ dishwasher, pots, pans, and washer/dryer at no additional cost. Fireplace & private deck. 3 parking spaces

A cozy living area features a patterned sofa with a red accent pillow, complemented by warm wooden flooring. A brick wall provides texture, and natural light filters through the windows. In the background, a dining area with a wooden table and chairs can be seen, along with a staircase.

4.98 out of 5 average rating, 115 reviews

Cottage in Lowertown–Perfect for Mayo & Downtown

In Lowertown-this quaint cottage with modern updates is your home away from home! Fully furnished and a well stocked kitchen make it a wonderful place for overnight stays or longer term rentals. Beautiful patio provides an urban sanctuary at the end of a long day. Close proximity to Mayo Clinic-downtown restaurants, grocery stores and shopping are within walking distance. Two blocks in either direction puts you on the trail system. Public transit 1 ½ blocks away and a laundromat is ½ block away.

A spacious living area features warm wood beam ceilings and large windows, allowing natural light to fill the room. Modern furniture, including a comfortable white sofa and a glass dining table, is arranged to create an inviting space. Double doors lead to a backyard patio.

4.95 out of 5 average rating, 268 reviews

Euro House, Bright! Near Mayo-Single Family Home

Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

A bright living area features a yellow chaise lounge, a dark upholstered chair, and a wooden table with books. A textured rug adds color underfoot. The wall is adorned with light-colored bricks and two windows with bamboo blinds. A TV is mounted for entertainment.

4.97 out of 5 average rating, 151 reviews

The Little House | 1 mi from downtown, Love Pets!

The Little House is the perfect place of you're looking for something Cozy, stylish, and close to everything that you need. This home was a fun renovation project for my husband and I. It's located in the family friendly Sunnyside Addition neighborhood and we've worked hard to make sure you have everything you need during your stay. This home has a beautiful fully fenced in yard with a neighborhood feel while still being less than a 5 minute drive from Downtown & Mayo Clinic Campuses!

A welcoming book titled 'Welcome to Oasis' is displayed prominently, featuring a lotus flower design and neatly placed beside a decorative white vase. Greenery is visible in the background, adding a touch of nature to the inviting setting.

4.95 out of 5 average rating, 130 reviews

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

The exterior of the home features a welcoming entrance with a porch, adorned with an American flag. The driveway leads to an attached garage, and landscaped green areas surround the entrance, creating an inviting approach.

5 out of 5 average rating, 156 reviews

Convenient, comfortable rambler near Mayo Clinic

• 1 mile to Saint Marys hospital and Mayo Clinic (Gonda) • Main level living — one 1 step up to front door • King bed, queen bed and daybed • Attached garage — huge perk in Minnesnowta! • Smart TVs w sectionals on main floor & basement, smart TV mounted in primary bedroom and a Roku TV in the queen size bedroom. • Two work spaces • Walk-in shower with grab bar • Serene rear patio with gas grill • Quiet neighborhood near Soldiers Field park, Apache Mall and biking/walking trails

Home in Historic Southwest

The open-concept living area showcases vaulted ceilings and skylights, enhancing natural light. Two light grey sofas frame a wooden coffee table on a colorful area rug. A dining area with a large table and chairs is visible, with stairs leading to the upper level in the background.

4.97 out of 5 average rating, 193 reviews

Spacious Modern Home Near Mayo, St. Mary's Campus

- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

4.96 out of 5 average rating, 142 reviews

The living area is highlighted by a modern gray sofa, accentuated with textured cushions. A sleek coffee table holds a glass vase with greenery, while art pieces adorn the wall. Natural light filters through sheer curtains, creating a bright and inviting space.

Home in Kutzky

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★

Welcome to Asfar house! Expertly designed and centrally-located in a desirable Kutzky Park neighborhood, walking distance to Mayo Clinic, restaurants and shops. Whether you are relocating or visiting Rochester, this house will be sure to impress. Blasting fast WIFI, 3 relaxing bedrooms & a fully equipped kitchen. A perfect retreat to enjoy the coffee bar, read, watch a Netflix episode, play and relax. Enjoy the perfect shower, conveniently adjoined with free washer and dryer.

4.91 out of 5 average rating, 154 reviews

A dining area is showcased with a wooden table surrounded by six chairs, highlighting a welcoming space for meals. Natural light filters through the open doorway, illuminating the adjacent living room, which features a comfortable sofa and a front door with glass panes.

Home in Kutzky

Entire Spacious House, 1/2 block from St. Marys

Older charming home! Less than one block from St. Mary's hospital. Ideal space for clinic patients and their families. Entire residential home with on-site parking for up to 3 cars. Located in the heart of Rochester Minnesota, within walking distance to Mayo Clinic and many necessities such as grocery stores, coffee shops, mayo shuttles, and restaurants. This location is a perfect home away from home, fully stocked kitchen, comfortable beds, and lots of room to spread out!

A cozy bedroom features slanted ceilings with soft gray walls. A spacious bed is adorned with a striped gray and white blanket, flanked by two nightstands with lamps. Art pieces decorate the walls, and a window allows natural light to illuminate the room.

4.87 out of 5 average rating, 522 reviews

Cottonwood Cottage

This beautiful 3 bedroom home is just 12 blocks from Mayo. It has plenty of space for your family. It has a nice kitchen with quartz counters. It also has a large living room with game corner, work area and Roku TV for all your streaming services. The home is located on the end of a quiet street and access to Rochester's vast walking/biking trails starts right out the front door. There is also a back patio with seating and a gas grill.

A bright bedroom features a spacious bed with white linens and a decorative pillow. A bedside lamp emits soft light beside a window with light curtains. A green dresser and a mirror complement the neutral walls, adding a fresh touch to the space.

4.97 out of 5 average rating, 381 reviews

The Guesthouse Cottage, walkable to Mayo Clinic

Our Guesthouse has a clean cottage feel. The king and queen bedrooms offer closets and quality linens. Cook meals in a fully stocked kitchen. Book an Uber, or walk 0.6 miles to Mayo's main Gonda building. We're close to grocers, coffee, parks and trails, and downtown's restaurants, shops, and a lovely public library. Free washer and dryer on site. Google TV and internet. 3-season porch. Small guest garage. No smoking on the property.

4.96 out of 5 average rating, 171 reviews

The Sierra! Close to Mayo Clinic

Gorgeous Home close to Mayo Clinic. The family room and living include Roku 4K UHD TVs, Foosball, and darts. Free WIFI. Office on Main with great light. Beautiful front porch or patio in the rear. TVs Enjoy luxurious finishes like crown molding, a fireplace in the family room, quartz countertops and a stunning vaulted Primary Ensuite with custom tile work and paneled doors. All of this is conveniently just minutes from downtown!

Popular amenities for Rochester house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

The exterior of a modern two-story home showcases a contrasting black and white color scheme. A spacious driveway leads to a large, white garage door. Clear blue skies serve as a backdrop, and well-maintained landscaping frames the property.

4.86 out of 5 average rating, 7 reviews

4bd/2.5bth Single-Family Home Close to Mayo

A modern two-story single-family home is depicted, featuring a clean white and black exterior. A large garage door complements the ample driveway. The well-maintained lawn offers a green backdrop, while the sunlit blue sky enhances the overall inviting appearance of the property.

5 out of 5 average rating, 8 reviews

4bd/2.5bth Single-Family Home Close to Mayo

Superhost

A modern single-family home is depicted, featuring a sleek black exterior with a prominent garage. The driveway leads to a well-maintained lawn, flanked by young trees and ornamental grasses, creating an inviting entrance. Clear blue skies complete the serene setting.

5 out of 5 average rating, 5 reviews

Unit 2377J | 3bd/2bth | Single-Family Home

A serene outdoor space is highlighted by a stunning sunset over lush greenery. Comfortable seating is arranged around a fire pit, surrounded by blooming flowers and various plants. A swimming pool is visible in the background, nestled into the landscape.

5 out of 5 average rating, 47 reviews

RARE! Pool, hot tub, garden &chickens! 4m to Mayo

A modern single-family home showcases a dark exterior with a spacious two-car garage. The front yard is neatly landscaped, featuring green grass and a young tree. A covered porch provides shaded entry, with large windows allowing natural light to stream indoors.

5 out of 5 average rating, 12 reviews

Unit 2365J | 2bd/2bth | Single-Family Home

Weekly house rentals

A comfortable living area is showcased with a spacious sectional sofa and a small side table. Natural light fills the space through large windows, and a dining area is visible in the background. Decorative plants add a touch of greenery to the inviting environment.

5 out of 5 average rating, 27 reviews

The Little Blue Inn

A comfortable living area features a modern sectional sofa and a wooden coffee table. A ceiling fan provides a refreshing breeze, while an electric fireplace adds warmth. Natural light fills the space from nearby windows, and elegant wall art enhances the relaxed atmosphere.

4.9 out of 5 average rating, 78 reviews

Chic 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets

An inviting living room features a dark sofa, a patterned armchair, and a coffee table at its center. Artwork adorns the walls, while light streams in through a window covered with curtains. A cozy area rug adds warmth to the wooden floor.

4.94 out of 5 average rating, 69 reviews

Come From Away!

A modern kitchen features white cabinetry and stainless steel appliances, including a refrigerator and oven. An island with seating for two enhances the space, while natural light enters through a window above the sink. Sleek countertops provide a clean and functional workspace.

4.99 out of 5 average rating, 82 reviews

Apple Hill guest house close to Mayo Clinic

4.91 out of 5 average rating, 22 reviews

3BR/2BA-10 Min’s to Mayo Clinic-Walk to Silver Lk

The living area features a spacious layout with a combination of modern and comfortable seating arrangements. A large window allows natural light to fill the space, while a mounted TV and decorative wall art enhance the ambiance. A fireplace adds a classic touch to the room.

4.87 out of 5 average rating, 47 reviews

The Loft & Nook: Modern Comfort + Spacious Livin’

4.97 out of 5 average rating, 29 reviews

Medcity Manor

A modern kitchen is presented with white cabinetry and stainless steel appliances. A spacious countertop emphasizes the cooking area, while a dining table with black chairs is seen nearby. Natural light enters through a skylight, enhancing the airy atmosphere of the space.

4.97 out of 5 average rating, 37 reviews

Big Family Fun (BFF) House

Private house rentals

Home in Historic Southwest

A two-story home with a stone facade and large windows sits on a well-maintained lawn. The entrance includes a small set of steps leading up to the front door. A driveway offers access to the house, surrounded by mature trees and landscaping.

4.98 out of 5 average rating, 49 reviews

3BR House Close to Mayo Clinic

The living room features a light-colored sofa paired with two antique armchairs. A wooden fireplace with a flat-screen TV above sits opposite a dining area. Rich wooden accents and natural light enhance the inviting atmosphere of the space.

4.74 out of 5 average rating, 114 reviews

441-Walk to Mayo St Mary-Victorian 4 BR House

An open-concept living area features a dining table with wooden chairs at the forefront. Beyond, a well-equipped kitchen is visible, alongside a cozy seating area with a sofa. Recessed lighting illuminates the space, enhancing the welcoming atmosphere.

4.97 out of 5 average rating, 90 reviews

Spacious 2BR Flamingo Suite - Minutes From Mayo

A dining area features a black rectangular table surrounded by six white chairs. A vase with decorative branches sits at the center of the table. A sliding glass door opens to an outdoor deck, with natural light illuminating the space.

4.96 out of 5 average rating, 24 reviews

Harvest Moons

A bright kitchen area is featured, showcasing wooden cabinetry with glass-front doors. A modern black faucet is positioned over a neutral countertop, and a welcoming sign decorates the wall above. Natural light filters through the window, illuminating the backsplash tiles.

4.94 out of 5 average rating, 71 reviews

The Cozy Hope House -- Minutes from Mayo Clinic

Superhost

The exterior of a spacious home is highlighted by a welcoming white façade and a dark gray roof. Lush green grass surrounds the property, and several trees add a touch of nature. A paved driveway leads to an attached garage, enhancing the overall curb appeal.

4.77 out of 5 average rating, 13 reviews

Executive Home near Mayo Clinic

The living area features a comfortable sofa and armchair beside a large window, offering views of the surrounding nature. A coffee table sits centrally, adorned with a decorative plant. Light fixtures hang from the ceiling, providing a warm ambiance.

5 out of 5 average rating, 23 reviews

House in the trees with City View (Haakon House)

A spacious bedroom features a modern wooden bed topped with white bedding, flanked by matching bedside tables with lamps. A neutral-toned throw blanket is draped across the foot of the bed. An elegant piece of wall art adds character to the room, while polished hardwood floors complete the design.