Apartment holiday rentals in Rochester

A garden-level apartment is accessed via a gravel driveway that leads to a charming home. Lush greenery surrounds the path, and the structure features a mix of siding colors, with large windows framed by blue shutters, creating an inviting exterior appearance.

4.94 out of 5 average rating, 226 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

The main living area features a spacious blue sofa accented with decorative pillows. Two vibrant orange chairs are positioned around a dark wood coffee table. A large flat-panel TV displays the Roku interface, enhancing the modern entertainment options available.

4.97 out of 5 average rating, 36 reviews

Upscale King Suite—Steps from Mayo Clinic Hospital

This luxury suite is a private wing on the 2nd floor of a newly renovated 3-story mansion. Conveniently located in one of the trendiest neighborhoods in Rochester. Steps from the Mayo Clinic St. Mary's hospital, Starbucks & Caribou coffee, restaurants, grocery stores, nightlife & downtown. FEATURES High speed internet 75” HD LED TV Workspace High-end interior King size beds Washer/dryer Fully stocked kitchen Free garage parking Keyless entry Super convenient for short-term or long-term stays.

A spacious living room is showcased, featuring a large dark sectional sofa with a light throw blanket. A television unit stands against one wall, while a small table with decor is positioned beside a chair. Soft lighting creates a cozy ambiance.

Apartment in Byron

4.71 out of 5 average rating, 14 reviews

Calm & Comfort | 12 Min to Mayo

- Enjoy a peaceful and private lower-level apartment 12 MINUTES TO MAYO -A spacious living room & bedroom, convenience station, plus a full bathroom with a relaxing shower -This stylish place has ample storage and Private entrance. Please note: your host lives on the upper level, but your space is completely private and secure, with host available if you need anything. - Whether you’re here for medical visits or a getaway, this home provides the perfect balance of comfort and convenience.

A cozy bedroom features a wooden bed frame with a light comforter and pillows. Nightstands with lamps are positioned on either side, providing soft lighting. A dresser sits against the wall, complemented by a decorative plant and an art piece. Natural light is softly diffused through the window curtains.

4.97 out of 5 average rating, 61 reviews

The Nest on Broadway

Welcome to The Nest on Broadway. This quiet one bedroom apartment is situated on North Broadway, just a few blocks from downtown Rochester, with a free dedicated parking space and private entry on the back of the building. The door is also just steps away from the bus stop. This cozy abode features a classic retro style, queen bed, free wifi, and a dedicated workspace. Restaurants, Silver Lake, and other amenities are in close walking distance. You'll feel right at home settling into The Nest.

5 out of 5 average rating, 16 reviews

Lux 1 BR I 1 Block to Mayo Skyway I Parking I Pets

Welcome to your luxury refined home base in the heart of downtown Rochester. Located at The Maven on Broadway, this upscale one-bedroom apartment offers the perfect blend of comfort, convenience, and elevated living—just a short walk to the skyway connecting you in minutes to the Mayo Clinic System. Whether you’re here for medical care, professional work, or supporting a loved one, this thoughtfully designed space provides a calm, stylish space with all the amenities needed during your stay.

A welcoming living room is highlighted by a vibrant flower arrangement on a gold side table. A cozy couch faces a fireplace, with a television mounted above a white entertainment center. Musical decor and seasonal garlands add a touch of charm to the space.

4.83 out of 5 average rating, 42 reviews

Discount Charming 2 Bedroom Close to Mayo

Peaceful and centrally located cottage. This home is a beautifully furnished main-level triplex just 5 minutes from Mayo Clinic. Bus stop on property and multiple restaurants 3 minutes away. This 2-bedroom, 1-bath unit has everything you might need to recover from a surgery, to feel at home while seeking treatment or to enjoy beautiful Rochester. The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pets welcome at a charge of $50/pet/month.

Apartment in Historic Southwest

A two-story duplex is presented, featuring a symmetrical facade with bay windows and a front porch. A well-maintained lawn and landscaping enhance the entrance, which includes a set of white steps leading up to the front door. Clear blue skies create a bright atmosphere.

4.95 out of 5 average rating, 44 reviews

Step to Mayo Clinic | Free Parking | Private Unit

Welcome to our cozy home in Rochester’s historic Southwest neighborhood! We’re right across from the Mayo Clinic Downtown Campus and just four blocks from St. Mary’s Hospital—perfect for Mayo patients, visitors, or staff. This main-floor, two-bedroom unit features WiFi, FuboTV, a smart lock, and free use of a washer and dryer. Free parking is included, with space for a camper if arranged in advance. The area is quiet, safe, and mostly home to medical professionals. We’d love to host you!

A cozy living room space features a beige couch adorned with decorative pillows and a low coffee table. The white brick wall serves as a backdrop for a fireplace, which is framed by a wooden mantle decorated with artwork and a wreath. Natural light enters through a window.

4.97 out of 5 average rating, 267 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

4.88 out of 5 average rating, 249 reviews

SALE: Remodeled retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in summer 2018 • Brand new kitchen in March 2026 • 650 square feet • Upstairs apartment in quiet 4plex • Free off-street parking • 5 blocks north of Mayo Clinic • Walk-in tiled shower • Queen bed • Oversized power recline La-Z-Boy chair • Reclining leather loveseat • 43" Smart TV with DirecTV/cable • High-speed WiFI — 300 MBPS • Shared laundry in the basement • Huge windows for tons of natural light

A modern living space is showcased with large windows allowing natural light to fill the room. A comfortable black sofa is positioned facing a circular coffee table, while a cozy chair stands alongside. The sliding glass doors provide access to a private balcony with outdoor seating.

5 out of 5 average rating, 4 reviews

Peaceful Riverside 2Bed/2Bath w/balcony near Mayo

Welcome to The Lofts at Mayo Park, a river-view apartment nestled along the scenic Zumbro River in Rochester, MN. Offering the perfect blend of modern elegance and tranquility, this upscale stay is just minutes from downtown and the Mayo Clinic yet tucked away in a peaceful, private setting. Tenants may be seen lounging on the front porch, listening to drifting notes from the piano, and visiting the surrounding parks, riverside trails, and community facilities!

A spacious living room is highlighted by large windows allowing natural light, enhancing the soft blue walls. Features include a decorative area rug, a comfortable sofa with patterned upholstery, a wooden coffee table, and a smart TV. Two additional seating areas are provided by armchairs and a small side table.

4.92 out of 5 average rating, 50 reviews

St. Mary's Classic

This special place is close to everything, making it easy to plan your visit. Relax in this well-appointed and carefully curated one-bedroom apartment located one block from Mayo Clinic's St. Mary's Hospital. It is located on the third floor (no elevator) of the classic, early 20th century brick apartment building, Leland. The owner/host is a life-long Rochester resident. Quality, cleanliness and comfort are our motivation.

A bright kitchen area features modern appliances including a black stove and a white refrigerator. A dark wooden dining table is positioned centrally, surrounded by chairs. Natural light enters through sliding glass doors that open to a small outdoor space, enhancing the room's airy feel.

4.9 out of 5 average rating, 101 reviews

Beautiful Duplex home 5 minute walk to Mayo Clinic

This home is located in the heart of the historic Rochester, MN. Just a stones throw from the Mayo Clinic. This downtown area is packed with shops and eating establishments, all interconnected via the walking subway system, for those cold winter days. When the weather warms, beautiful parks and paths abound in an endless display of green natural space. I hope your travels are safe and look forward to meeting you.

Popular amenities for Rochester apartment rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Weekly apartment rentals

A modern kitchen is shown with stainless steel appliances, including a refrigerator and wall oven. The island features a light countertop, accompanied by two bar stools. Cabinets are installed above and below, ensuring ample storage space. Natural light fills the area through the adjacent windows.

5 out of 5 average rating, 12 reviews

Tranquil 2Bed/2Bath w/Balcony near Mayo

A modern kitchen area features stainless steel appliances, including a refrigerator and a built-in oven. A central island with bar seating for four is surrounded by warm wooden cabinetry and contemporary finishes. A doorway leads to a cozy sleeping area in the background.

5 out of 5 average rating, 4 reviews

Peaceful Riverfront 2Bed/2Bath w/Balcony near Mayo

A well-appointed bedroom features a spacious bed with a textured blue coverlet. Nightstands flank the bed, each with a lamp providing soft illumination. Light-colored curtains frame the oversized window, allowing natural light to brighten the warm hardwood floors.

4.9 out of 5 average rating, 191 reviews

NEW: Calming main floor retreat near Mayo Clinic

A spacious living room is presented with light blue walls and beige carpet. A comfortable sofa and striped armchair are visible, alongside a wooden cabinet and television. Natural light enters through large windows, creating a bright and inviting atmosphere. A dining table with chairs is positioned in the foreground.

4.95 out of 5 average rating, 22 reviews

St. Mary's Retreat

4.86 out of 5 average rating, 99 reviews

Large 1 BR in 4plex, 1 mile from Mayo.

The room features a four-poster bed with a soft blue bedspread and accent pillows, complemented by a wooden nightstand with a lamp. A cozy armchair and a patterned area rug enhance the warm atmosphere, while natural light filters through the nearby window.

4.95 out of 5 average rating, 55 reviews

Curated Classic a block from St. Mary's Hospital

The fully stocked kitchen features modern stainless-steel appliances, including a refrigerator and dishwasher. A spacious countertop island offers seating. Mosaic tile backsplashes and decorative accents enhance the contemporary design, while overhead lights provide bright illumination.

4.98 out of 5 average rating, 47 reviews

Oasis Luxe Suite—Steps from Mayo Clinic Hospital

A spacious living area features two light-colored sofas facing each other, creating an inviting social space. A wooden coffee table sits between them, complemented by a TV mounted on the wall and a fireplace below. Large windows allow ample natural light to fill the room.

5 out of 5 average rating, 43 reviews

The Gwen | 2 bd, fenced yard, upstairs apt, pets!

Private apartment rentals

A bright studio room includes a spacious bed with white bedding and decorative pillows. A wall-mounted television is visible, alongside two windows providing natural light. A small dining table with chairs sits nearby, adorned with fresh flowers, creating a welcoming and functional space.

Apartment in Historic Southwest

4.73 out of 5 average rating, 141 reviews

8076-WALK to Mayo-Charming Studio Apt Free Parking

4.79 out of 5 average rating, 200 reviews

EXCEPTIONAL, CONTEMPORARY 2BD/1 BA/ CLOSE TO MAYO

A cozy living area is furnished with two plush armchairs positioned around a small table. The rich burgundy carpet, adorned with floral patterns, complements the wooden trim of the room. Large windows allow natural light to fill the space, with a glimpse of the adjoining bedroom visible through an open door.

Apartment in Historic Southwest

4.43 out of 5 average rating, 7 reviews

One bedroom Apt walk to Mayo and St,Mary's.

A bright and inviting kitchen is equipped with modern stainless steel appliances, including a microwave and dishwasher. A wooden dining table with four chairs is placed centrally, while decorative orange and red wall accents add warmth to the space. Light wood flooring enhances the overall ambiance.

4.93 out of 5 average rating, 14 reviews

All you need! Close to Mayo/Downtown/Fairgrounds.

A cozy bedroom features a spacious bed with neatly arranged pillows and a navy throw blanket. Two lamps illuminate the nightstands flanking the bed. Wall art and a large mirror enhance the inviting atmosphere, while natural light filters in through nearby windows.

4.93 out of 5 average rating, 175 reviews

Home for the Traveler, a walk to St. Mary's

A well-appointed living area is highlighted by a brown couch adorned with decorative pillows. A mid-century modern coffee table is center stage on a patterned rug. Natural light fills the space through two large windows, and a blue accent chair adds a pop of color.

4.87 out of 5 average rating, 31 reviews

Fresh space near Mayo Clinic and downtown

5 out of 5 average rating, 6 reviews

Cozy Clinic Retreat

A private deck is shown with two chairs and a small table, overlooking a green backyard filled with trees. The pathway is visible, leading deeper into the yard's natural landscape, providing a serene outdoor space.

4.88 out of 5 average rating, 43 reviews

Viola Suite #2 | Quiet 2BR, Lg Yard, 3 Mi to Mayo!

Family-friendly apartment rentals

The studio apartment features a four-poster bed dressed in light bedding. Two pink armchairs offer comfortable seating next to a glass coffee table. A wooden desk and chair are positioned nearby. Natural light enters through multiple windows, illuminating the soft blue walls and decorative area rug.

5 out of 5 average rating, 5 reviews

The Cozy Classic

The kitchen features modern cabinetry and stainless steel appliances, including a microwave, oven, and dishwasher. A spacious countertop offers ample preparation space, while a stainless steel sink is positioned under a window inviting natural light. Cooking essentials and utensils are neatly arranged.

4.79 out of 5 average rating, 28 reviews

Remodeled 2nd-floor apartment blocks from Mayo

An open living area showcases a gray sofa and a green chair, complemented by a round wood coffee table. Two framed artworks are displayed on the light-colored wall, while modern kitchen appliances are visible in the background, illuminated by soft natural light.

4.08 out of 5 average rating, 12 reviews

Two Bedroom Luxury in Rochester

New place to stay

Cozy studio apartment (5 min walk to Mayo)

A cozy living room is furnished with a sectional sofa and two woven chairs, creating a comfortable seating area. Large windows are dressed with light curtains, allowing natural light to brighten the space. A colorful painting enhances the wall, while a television is positioned for easy viewing.

4.88 out of 5 average rating, 16 reviews

Soothing space, 5 minute drive to Mayo

A bright living area features a navy blue sofa with a decorative vase of yellow flowers on a coffee table. A wooden dining table is set in the background, accompanied by chairs. Two large windows allow natural light to fill the space.

5 out of 5 average rating, 16 reviews

Clean, cozy, close to Mayo & Fairgrounds.

A spacious living area is highlighted by a medium-firm queen bed and a Flexsteel loveseat. A small dining table is positioned alongside a television. Walls are adorned with framed images, while a door leads to a private entrance.

4.93 out of 5 average rating, 28 reviews

Cozy, Private Studio. Near Mayo/Downtown/Parks

The living area features a blue sofa and two bright orange chairs arranged around a wooden coffee table with a floral centerpiece. A mounted flat-screen TV is displayed on the wall opposite the seating. Soft lighting enhances the open, welcoming space.