
Villa holiday rentals in Los Santos Province
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Top-rated villa rentals in Los Santos Province
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El Nido, Jungle Villa with Pool at Venao
Escape to El Nido, a stunning 3-bedroom, 3-bathroom jungle villa offering the perfect blend of tranquility and modern comfort. Nestled in Playa Venao, Panama, this boho-chic home features vibrant interiors, breathtaking ocean views, and a private pool. Ideal for families, groups, or remote workers, El Nido is just 2 minutes from the beach and Venao’s lively center, where you’ll find top dining, activities, and local charm. With high-speed Wi-Fi, a fully equipped kitchen, and spacious living area

Villa Tortugas, Blue Venao/Beachfront Club
Enjoy a spectacular Villa, just a short 3-minute walk to the beach in the most exclusive gated community, with security guards, surveillance & parking. There are 2 bedrooms, each with a private bathroom and an extra bathroom for guests, full kitchen, living room, and a beautiful terrace to rest with friends and family. The house has a 65" Samsung Smart TV/Apple TV, 130MB Wi-Fi internet in each room, & air conditioning. Our facilities at the oceanfront clubhouse & restaurant are exquisite.

Playa Laska – Oceanfront Escape with Infinity Pool
Welcome to Playa Laska, a luxury beachfront villa where tropical elegance meets modern comfort. With three beautifully designed bedrooms, a private infinity pool, and open-air decks surrounded by lush greenery, every corner invites you to unwind, connect, and savor the ocean breeze. Start your mornings with the sound of waves, relax by the pool or stroll along the shore, and let evenings unfold with dining under the stars. Every corner is thoughtfully crafted for a seamless and relaxing stay.

Villa Verde - Luxury & Cozy Villa 1BR #26 BlueVenao
Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

Casa Almendra
A 3-bedroom luxury villa located on the pristine beaches of Cambutal, Panama. This beachfront paradise offers everything you need for a truly unforgettable stay... A spacious and elegantly designed living area, an open-concept kitchen, fully equipped with top-of-the-line appliances and breathtaking ocean views, and an oceanfront saltwater pool surrounded by comfortable loungers. Entirely off-grid with a state-of-the-art solar power system, your stay is not only luxurious but eco-friendly.

Super Private Beachfront 3BR Villa & Infinity Pool
Sky above, sand below, peace within ~ Welcome to la Dolce Vita! Located in Andromeda, an oceanfront gated community on the Azuero Peninsula. Andromeda villas offer amazing and unparalleled ocean views where you can be with the sights and sounds of nature at its most beautiful. Our sun-filled and stunning Villa is 3 bed / 3 bath for up to 4 adults and 3 kids Features a spectacular view, private pool and direct beach access. Fully equipped so you can feel at home and enjoy your getaway!

Casa Colibrí, Pedasi
Immerse yourself in this beautiful custom built villa, within walking distances to one of Pedasi’s best beaches. The villa has many things to offer you from a fully equipped kitchen, private pool, bbq area, along with WIFi. The villa offers a tropical retreat with an ocean view, a covered patio with chairs and table to sit while you enjoy a glass of wine and listen to the sound of the waves crashing. In the evenings sit and relax by the fire pit and listen to the water feature and ocean.

Villa Del Mar - Blue Venao 3 Bedroom
Villa Del Mar is a modern beach villa in the most luxarious resort in Playa Venao - 'Blue'. Only 2 minute walking distance from the beach and an exclusive beach club where you will have access to a stunning beachfront infinity pool, delicious restarunt, and a spacious relaxation area. The Blue community is a relaxed, central and secure gated community where you will always be just a few minutes walking distance from the best restaurant, surfing spots, parties and of course - the beach!

Esplendorosa | Ocean View Villa with Staff & Chef
7 Bedrooms | Up to 16 Guests Luxury Villa with Pool & Ocean View – Staff & Chef Included Welcome to Villa Esplendorosa, a high-end villa located just a short walk from Destiladeros Beach, in Pedasí, Panama. The villa offers an elegant oceanfront setting with on-site staff, ideal for a relaxing and worry-free stay. You will enjoy: • Private swimming pool • Stunning ocean views • Daily staff included (chef & housekeeping until 2:00 pm) • Home cinema area • Power generator and Internet

Villa La Piragua: 3BR Surfside Retreat: 5-7G
Welcome to Villa La Piragua, an enchanting sanctuary in Blue Playa Venao. Let yourself go in this tropical paradise with pristine beaches. This beautiful villa offers 3 comfortable bedrooms and 3 well appointed baths. Two bedrooms have dreamy queen beds, while the third features a bunk bed with a pullout and an additional twin bed. All bedrooms have smart TV's and WiFi. Enjoy a serene spacious atmosphere in the living area, kitchen, and terrace, ensuring a memorable family getaway.

Playa Venao Blue 12 | Luxury Beach Escape Villa
A 3 bedroom villa centrally located at Blue, A gated community in Playa Venao with everything at your doorstep. Just a few minutes walk to the beach, local shops, restaurant and grocery store. Access to an oceanfront beach club that hosts an infinity pool, restaurant and casual sitting area. Enjoy the best of Playa Venao a great surf spot for beginners and experienced surfers. Local tours, yoga and fitness, restaurants and music. Playa Venao offers something for everyone.

Villa "La Décima" comfortable property to enjoy!
We are located in the spectacular area near to Belisario Porras Park & Church of Santa Librada. Las Tablas City is well known for Carnival celebration, beautiful queens, great float parade, fireworks, music. The Town is a 10 minute walk distance & boasts a wide variety of restaurants, bars and shops. Local activities include: handicrafts, local museum, traditional dance, folklore, Panamenian local food, great rivers and beautiful beaches.
Popular amenities for Los Santos Province villa rentals
Private villa rentals

3min walk to the Beach 2BR Villa 20 at Playa Venao

Bohemian Villa 3BR at Playa Venao

Villa Ceviche, Surf Villa at the Heart of Venao

Casa Vida, Breathtaking Ocean View Villa

Beachfront Villa with Pool at the Heart of Venao

Pacific Escape

Playa Laska – Oceanfront Escape with Infinity Pool

Charming beach villa Pedasi, Panama
Luxury villa rentals

Playa Laska – Serene Oceanfront Villa with Pool

Casa Rosita 49' - VENAO BEACH

Luxury Beachfront Villa Estate with Private Pool

Beachfront Villa with Pool at the Heart of Venao

Loma Venao, Panoramic Oceanview Villa

Villa Paradise - Blue Venao 3BR

Villa Atlantis - Blue Venao 3BR

Villa by Casa de Campo
Villa rentals with a pool

Casa Tucán by LAR architects • Sea view Studio 01

Villa Ceviche, Surf Villa at the Heart of Venao

3-BR Villa with Infinity Pool

Casa Tucán by LAR architects • Sea view Studio 02

Esplendorosa | Ocean View Suites with Staff & Chef

VENAO - BLUE27 COZY VILLA

Villa Ocean Pearl 2 Bedrooms 2 Baths at Blue Venao

Family Surf Villa with Resort Amenities at Venao
Destinations to explore
- Smoking-friendly rentals Los Santos Province
- Guesthouse rentals Los Santos Province
- Bed and breakfasts Los Santos Province
- Pet-friendly rentals Los Santos Province
- Rentals with a hot tub Los Santos Province
- Apartment rentals Los Santos Province
- Rentals with pools Los Santos Province
- Beachfront rentals Los Santos Province
- Waterfront rentals Los Santos Province
- Boutique hotels Los Santos Province
- Rentals with outdoor seating Los Santos Province
- Hotel rooms Los Santos Province
- Rentals with beach access Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Condo rentals Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- House rentals Los Santos Province
- Rentals with a washing machine and dryer Los Santos Province
- Rentals with a fire pit Los Santos Province
- Villa rentals Panama




