
House holiday rentals in Los Santos Province
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Top-rated house rentals in Los Santos Province
Guests agree: These houses are highly rated for location, cleanliness and more.

Beachfront Gem w/ Ocean Views & Prime Surf Access
Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.
ValueFamilyOutdoor spaces
4.97 out of 5 average rating, 37 reviews
Nearly Oceanfront: Blue 3 Bedroom Spacious Villa
Villa-33, your exquisite retreat nestled within Blue Playa Venao. Discover a tropical paradise of stunning beaches. Embark on endless adventures just a short walk away. This beautiful Villa offers 3 bedrooms and 3 baths. Two of the bedrooms feature queen beds, while the third bedroom has 2 twin beds, ensuring a restful night's sleep for everyone. The living area, kitchen, and terrace are thoughtfully equipped with everything you need to make yourself at home during your fun family getaway.
FamilyLocationKitchen
5.0 out of 5 average rating, 40 reviews
Peaceful Pedasi
Peaceful Pedasi. Get completely away from the city and forget the rest of the world exists. Pedasí is a town and corregimiento situated on the south-eastern tip of the Azuero Peninsula on Panama’s Pacific coast. And although remote enough to feel protected from the stresses of life, Pedasi offers wonderful dining and shopping. Our home offers a full functioning kitchen, large dining space, 5 Bedrooms, 4 Bathrooms, 2 car garage, private pool, and cabana with your own view of the ocean.
LocationFamilyBarbecue
4.87 out of 5 average rating, 23 reviews
NinaHouse, spacious and cool house in Chitré.
House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.
ValueFamilyBackyard
4.82 out of 5 average rating, 84 reviews
Casa Gerard
A stylish, modern beach house perched above the Pacific Ocean and a large stylish pool. Ample space with 3 bedrooms with en-suite bathrooms, large open living space with a fully equipped kitchen, giving onto a large wooden deck. A beach house with a pool in a modern style located on the hill overlooking the Pacific Ocean. It has 3 bedrooms, each with its own bathroom. It has an open living room and a well-equipped kitchen. It has a large deck to enjoy.
ValueLocationBeach
4.81 out of 5 average rating, 16 reviews
Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.
LocationFamilyAccess
4.98 out of 5 average rating, 84 reviews
Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.
ValueLocationWi-Fi
4.9 out of 5 average rating, 84 reviews
Tropical Cozy Cabin / Playa venao
Welcome to our tropical & cozy private cabin, fully furnished and equipped with everything you need for a comfortable stay in Playa Venao. Central location (2 min drive from the beach) Features two bedrooms with 2 single beds each, cozy living room with TV and sofa, fully equipped kitchen, AC in all the rooms, one bathroom and outdoor shower. Also have a nice terrace area with a deck and a comfy dining lounge.
LocationValueIndoor spaces
5.0 out of 5 average rating, 14 reviews
A minimalist Casita in Pedasi
Imagine a peaceful casita with ocean views and a nearby pool house boasting an edgeless pool overlooking the ocean. Plus, you have your own private beach. Inside, you will find an open-concept living space adorned with simple yet stylish furnishings, designed for relaxation and comfort. It's the perfect blend of tranquility, peaceful seclusion and breathtaking natural beauty. Gated community, 24 hour security
LocationFamilyAccess
4.91 out of 5 average rating, 35 reviews
Casa Inito - Romantic Getaway
Indulge in the charm of Casa Inito, a thoughtfully crafted haven that invites you to experience a one-bedroom retreat like no other. This well-designed space seamlessly blends modern comfort with an intimate setting, creating the perfect atmosphere for your getaway. The Villa is located just 7 minutes from Playa Venao Beach (by car). ****(Vehicle a MUST, preferably SUV due to steep paved access road)****
LocationGetting aroundAccuracy
4.95 out of 5 average rating, 22 reviews
Beach side stay at Casa Blanca
This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.
LocationFamilyPets
4.96 out of 5 average rating, 49 reviews
Private Pool · Fenced Yard · 5m to Beach & Town
Your private tropical oasis in Pedasí’s secure Roy’s Community. Stroll 10 min to the beach, unwind by your private pool, and enjoy a fully fenced yard with ice-cold A/C throughout. A proven 4.92-star Guest Favorite with 200+ reviews, featuring 2 en-suite bedrooms (King & Queen) and a fully equipped kitchen. Dogs welcome!
LocationValueLong stay
4.92 out of 5 average rating, 200 reviewsPopular amenities for Los Santos Province house rentals
House rentals with a pool

Casa - Domaine De La Rose
LocationFamilySleep quality
4.89 out of 5 average rating, 19 reviews
Casa Ola – Steps from the Beach | Pool & BBQ Oasis
LocationValueKitchen
4.93 out of 5 average rating, 14 reviews
Casa Carolina: Spacious 3 Bedroom at Blue Venao
FamilyLocationLayout
4.89 out of 5 average rating, 18 reviews
Tropical Oasis, Full House, Private Pool,
LocationValueOutdoor spaces
4.89 out of 5 average rating, 19 reviews
Casa Del Amor in Pedasi, Panama Oceanfront paradise
ComfortPoolHospitality

Oceanfront Loft with Private Beach & Pool

Luxury Villa

Beachfront home on Playa Venao + private pool
ValueFamilyComfort
4.9 out of 5 average rating, 157 reviewsWeekly house rentals

Casa Blu Central Chitre| Sleeps 6| Private Parking
FamilyLocationParking
5.0 out of 5 average rating, 11 reviews
House "Las Marias"
LocationFamilyWalkability
4.55 out of 5 average rating, 44 reviews
Breathtaking Views: Sleeps 13, Walk to Beach!
FamilyLocationAir conditioning
5.0 out of 5 average rating, 20 reviews
Our Happy Place
ValueLocationSleep quality
4.84 out of 5 average rating, 55 reviews
Entire House at Beach Haven
FamilyLocationAccess
5.0 out of 5 average rating, 3 reviews
House in Plaza Praga - Las Tablas
LocationCleanlinessGetting around
5.0 out of 5 average rating, 6 reviews
Cozy country-style house.
FamilyLocationIndoor spaces
4.61 out of 5 average rating, 23 reviews
Pedasi Craftsman Home/Walk to Town
LocationValueKitchen
4.84 out of 5 average rating, 32 reviewsPrivate house rentals

Villa Sirena – Blue Venao (2BR)
LocationBeachQuiet
5.0 out of 5 average rating, 3 reviews
Luxury Spanish-Style Beachfront Villa | Long Term
FamilyLocationAccess
5.0 out of 5 average rating, 10 reviews
6 Bedroom 6 bathrooms up to 16 guests
FamilyLocationNearby
5.0 out of 5 average rating, 5 reviews
Modern Beach Home with pool and hot tub
ValueFamilyAccess
4.9 out of 5 average rating, 21 reviews
Pedasí: Andromeda Boroda 4-6 p. Beach, swimming pool
LocationValueCondition
4.93 out of 5 average rating, 54 reviews
Beachfront Home w/key to empty beach
ValueFamilyQuiet
4.96 out of 5 average rating, 23 reviews
House for groups/Perfect for Local Parties
ValueLocationCleanliness
4.68 out of 5 average rating, 19 reviews
Dorado Retreat Estate in Cañas
FamilyLocationView
5.0 out of 5 average rating, 6 reviewsDestinations to explore
- Pet-friendly rentals Los Santos Province
- Bed and breakfasts Los Santos Province
- Rentals with pools Los Santos Province
- Rentals with beach access Los Santos Province
- Hotel rooms Los Santos Province
- Condo rentals Los Santos Province
- Boutique hotels Los Santos Province
- Beachfront rentals Los Santos Province
- Rentals with a hot tub Los Santos Province
- Waterfront rentals Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Villa rentals Los Santos Province
- Family-friendly rentals Los Santos Province
- Apartment rentals Los Santos Province
- Guesthouse rentals Los Santos Province
- House rentals Panama





