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Apartment holiday rentals in Los Santos Province

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Los Santos Province

Guests agree: These apartments are highly rated for location, cleanliness and more.

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Superhost
Apartment in Las Tablas
4.58 out of 5 average rating, 40 reviews

1st Floor Beach Apartment with ocean views!

Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock or rocking chair. This 1 bedroom/1 bath 1st floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get streaming smart TV, unlimited bandwidth Wi-Fi internet, and hot water showers. This apartment is perfect for a couple.

Guest favourite
A spacious living area is showcased with large windows allowing natural light to fill the room. Comfortable seating is provided by a neutral-toned sofa adorned with decorative pillows. A round coffee table and woven ottoman complement the space, with a dining area visible in the background.
Apartment in Las Escobas del Venado
4.95 out of 5 average rating, 127 reviews

LUXURY Apartment in BLUE Playa Venao B-32

Brand new 2 bedrooms luxury apartment, fully equipment, well organized for families, friends or even just for you. All you need for the perfect relaxed vacation, just bring your clothes and good energy and we will take care for the rest. Located in the best location, in the middle of everything (but still very quiet). A very short walking to the beach (with direct access), restaurants, bars, shops, supermarket, surfing schools, Yoga & wellness centers, horses riding, ATM and a gas station.

Guest favourite
Apartment in Las Tablas
4.94 out of 5 average rating, 17 reviews

Loft Conivan-Las Tablas

Enjoy Las Tablas as if you were at home in this spacious and comfortable full apartment. Located on the first floor. Equipped for short or long stays, with a full kitchen, cozy living room, air conditioning and WiFi, ideal for all types of travelers. Beaches, restaurants, supermarkets, and the town's main tourist attractions are just a few minutes away. Whether you're coming for a celebration, rest, or a walk, this home is the perfect starting point to enjoy Las Tablas.

Guest favourite
Apartment in La Villa de los Santos
4.86 out of 5 average rating, 7 reviews

La Villa accommodation for 2 people

Disfruta de una estancia cómoda y tranquila en este apartamento ubicado en el centro de La Villa de Los Santos. Perfecto para parejas o viajeros que buscan descanso y buena ubicación. El espacio incluye: • 1 habitación con cama cómoda • 1 baño privado • Sala con TV • Cocina equipada • Comedor 📍 Ubicación céntrica, cerca de comercios y puntos importantes. 🔒 Nota: El alojamiento cuenta con una segunda habitación que no estará disponible en esta modalidad.

Superhost
Apartment in Las Escobas del Venado
4.83 out of 5 average rating, 6 reviews

Exclusive & Modern Loft | Close Beach | AC, Pool

Brand new modern loft in Playa Venao, surrounded by lush nature and minutes from the beach. Stylish 1BR, 1.5BA apartment with king-size bed and handcrafted wood furniture. Fully furnished with A/C, Smart TV, high-speed WiFi, sofa lounge, and fully equipped kitchen (gas stove, microwave, dishwasher). Solar water heaters and backup generator ensure a comfortable, reliable stay—perfect for surfers, couples, and digital nomads seeking style and tranquility. 🌿🏄‍♂️

Guest favourite
The open-concept living and dining area features a large wooden table surrounded by eight chairs. A cozy L-shaped sofa and a lounge chair offer seating options. A flat-screen TV is mounted on the wall, and shelves display decorative plants and tableware.
Apartment in Las Escobas del Venado
5 out of 5 average rating, 8 reviews

Lovely FamilyFriendly 2BR Condo D11 in Playa Venao

Welcome to Condo D-11! Nestled in the heart of BlueVenao on the stunning Azuero Peninsula, this tropical paradise offers a unique beachfront experience with miles of pristine coastline. Just a short stroll away, you'll find yourself on the sand, ready to embrace new adventures! This bright and airy condo features a King Bed with an ensuite bathroom in one bedroom and a cozy Queen Bed in the second—perfectly set up for your ultimate tropical escape

Guest favourite
Apartment in La Pasera
4.83 out of 5 average rating, 6 reviews

Comfortable apartment in Las Tablas, quiet area

Apartamento nuevo, muy cómodo y con mobiliario de lujo, diseñado para una estancia acogedora y elegante. Ubicado en una zona tranquila de Las Tablas, a 7 minutos del parque y a 15 minutos de las playas. Dispone de camas muy cómodas con colchones de alta gama y sábanas de alta calidad hotelera para un descanso reparador. Cuenta con zona de coworking y TV con streaming. Cocina completamente equipada. Ideal para disfrutar con total tranquilidad.

Guest favourite
A light-filled living space features a comfortable sofa and a rustic wooden coffee table. Large glass doors open to a balcony, enhancing the scenic view. A dining table with wooden benches and a modern kitchen area are visible, blending functionality with style.
Apartment in Las Escobas del Venado
4.98 out of 5 average rating, 52 reviews

Stunning Oceanview Condo

A new, beautiful 2 bedrooms apartment, in the Blue Venao Beach Resort in Playa Venao. The apartment is located in the new building overlooking the water. It is fully equipment, and located in the heart of the surf town, one minute from the hectic night-life scene, yet in a quiet and peaceful area. The exclusive beach resort offers an infinity pool, beautiful bar & social area, and direct access to the beach.

Guest favourite
The living area is furnished with a comfortable gray sofa, a round coffee table, and a wall-mounted TV. Natural light enters through sliding glass doors that lead to an outdoor space, complemented by a ceiling fan and a woven light fixture.
Apartment in Las Escobas del Venado
4.95 out of 5 average rating, 19 reviews

Homz Venao, Private Balcony Apt

Welcome to Venao Homz Apartment - Your home away from home! This cozy getaway is located at Playa Venao's prime spot, only 2 minutes walk from the beach and adjacent to Venao's most known restaurants, bars and supermarket. With speedy Wifi, modern amenities, fully equipped kitchen , a sea-view balcony and comfortable furnishings - we strive to create a warm, home-like environment for our visitors.

Guest favourite
Apartment in La Villa de los Santos
4.88 out of 5 average rating, 8 reviews

Victoria Apartment #2

In Victoria Apartment No. 2 You will find a quiet accommodation very close to the Church and Simón Bolívar Park, places where the different and renowned festivals of Villa de Los Santos are concentrated. You will also find a lot of comfort with good internet, which makes it a place to enjoy as a family or for work.

Superhost
A modern living space features a light-colored sectional sofa with vibrant red and blue cushions. In the background, an open kitchen includes stainless steel appliances and wood cabinetry, while large windows allow natural light to fill the area.
Apartment in Las Escobas del Venado
4.86 out of 5 average rating, 44 reviews

Blue Venao Coastal Charm 2BR / Condo D31

❤ We introduce you Condo D31, perfect for enjoying a beach vacation with your family, it has 2 bedrooms and enough comfort to stay up to 5 people. Located less than 3 minutes from the beautiful Playa Venao, where you can enjoy surf, yoga, restaurants and beautiful sunsets. Don't think twice and stay at condo D31!

Superhost
A spacious living area features a light grey sofa and a wooden coffee table. Large sliding glass doors lead to a balcony with views of the surrounding greenery. Two wicker light fixtures hang above the kitchen island, adding a natural element to the modern design.
Apartment in Las Escobas del Venado
4.86 out of 5 average rating, 28 reviews

Your Beachside Oasis at Venao

Welcome to your stylish 2-bedroom retreat in the heart of the coveted Blue Venao Beach Resort—the ultimate blend of modern luxury and laid-back coastal charm. Perfectly positioned just minutes from the golden shores, this apartment offers everything you need for a tranquil or adventure-filled getaway.

Popular amenities for Los Santos Province apartment rentals