Guesthouse holiday rentals in La Mesa

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Popular amenities for La Mesa guesthouses

Family-Friendly guesthouses

Top Guest favourite
Guesthouse in Talmadge
4.98 out of 5 average rating, 209 reviews

Lovely Guesthouse in garden setting

RamonaRating, 5 stars6 months ago
We are so grateful to have been able to stay at Gwynn's place, it is so peaceful and lovely. Like a secret garden getaway. We loved all the small touches, and beauty of the space. Gwynn made us feel very welcome and comfortable! The pool is amazing and the outdoor spaces are delightful. Can't wait to stay here again.
Guest favourite
Guesthouse in La Mesa
4.93 out of 5 average rating, 239 reviews

Fig Tree Bungalow

DeshawnRating, 5 stars1 week ago
This place was great and the owner was very helpful.
Top Guest favourite
Guesthouse in Allied Gardens
4.95 out of 5 average rating, 400 reviews

The BEST NEST Clean, peaceful, private, affordable

AaswathRating, 5 stars1 week ago
A perfect place for our family during our short stay in San Diego. Clean, comfortable, conveniently located and excellent value. Teri also went above and beyond and we really appreciated her proactive help.
Top Guest favourite
Guesthouse in Greater North Park
4.97 out of 5 average rating, 186 reviews

New Guest House - North Park

KrystenRating, 5 stars3 weeks ago
Lynae’s place was wonderful, as was Lynae! Balboa park right nearby, with gorgeous trails and scenery. Walkable to North Park area which had a fun variety of bars, shops, and restaurants. Lynae was a wonderful host - responsive, kind, flexible - and the home was bright, airy, with gorgeous views. We couldn’t say enough good things about the wall of jasmine walking in. Thank you Lynae for having us in your home!
Top Guest favourite
Guesthouse in Jamul
4.95 out of 5 average rating, 223 reviews

Retreat house. Nature, Hot Tub, Views!

BrandonRating, 5 stars6 days ago
⭐️⭐️⭐️⭐️⭐️ A Soulful Retreat at Cloud Mountain We had the most peaceful and restorative stay at this guest home in Jamul. My partner was recovering from a hospital stay, and this place offered everything we needed—quiet, nature, and healing energy. The guest house was spotless and cozy, with thoughtful touches. We did yoga on the deck, hiked among boulders, watched every sunrise and sunset, and soaked in the hot tub under the stars. The coastal breeze, birdsong, and privacy made it feel like a true escape. We loved connecting with the warm, welcoming hosts and their family as well as their sweet animal companions both cats and dogs—including a very friendly pig named Violet! We hardly heard a single car or plane during our stay. If you're looking to reconnect with nature, this is the place. We left feeling calm, refreshed, and recharged—and we’ve already planned our return to Cloud Mountain. No need to look any further—this place is something special!!! ⭐️⭐️⭐️⭐️⭐️
Top Guest favourite
Guesthouse in Talmadge
4.96 out of 5 average rating, 160 reviews

Private Guesthouse with Amazing Views

StacyRating, 5 stars2 weeks ago
This is a favorite stay in the San Diego area for us for several reasons. When we walk into the studio, we feel at home immediately. The kitchen is stocked with morning coffee and tea supplies. There are welcome sodas in the fridge and snacks in the cupboard. The unit is clean and the bed is comfortable. The cottage feels private with a balcony overlooking a canyon. There is plenty to do within 15-30 minutes of driving time. The location is safe. Kristin, the host, is very responsive. We have had no issues what so ever with any of our stays.
Guest favourite
Guesthouse in San Diego
4.93 out of 5 average rating, 195 reviews

Cosy quiet Guesthouse near SDSU

SandyRating, 5 stars3 weeks ago
Desiree is such a sweet host! My husband, five month old, and I stayed in her Airbnb and we very much enjoyed our time. The place was well kept and clean. She had the guest house stocked with all the essentials which made it so nice and convenient. Anytime we had a question or request, she was quick to respond and resolve. The location is close to many great coffee shops, restaurants, and things to do. Glad we found this place and would definitely book it again in the future!!
Top Guest favourite
Guesthouse in Chula Vista
4.95 out of 5 average rating, 560 reviews

Private Casita in Great Eastlake Neighborhood

EricaRating, 5 stars2 weeks ago
Wonderful spot and perfect for a little weekend visiting family. Super safe and beautiful neighborhood! The bed and linens were extremely comfortable and I slept like a baby. I would definitely stay here again when I’m the area. Thanks David!

Guesthouses with a patio

Top Guest favourite
Guesthouse in Poway
4.98 out of 5 average rating, 108 reviews

Gorgeous Guesthouse Poway w/Private Yard

ToniRating, 5 stars1 week ago
We had a great stay. The place was very clean, private, and beautifully decorated. It felt comfortable and welcoming. Would happily stay here again.
Top Guest favourite
Guesthouse in La Jolla
4.98 out of 5 average rating, 209 reviews

La Jolla Oasis: Ocean, City and Fire Works Views

MarrisRating, 5 stars3 weeks ago
The space is stunning, spacious with modern decor and beautiful views. Atoosa has anticipated everything you will need to enjoy your vacation, from coffee to complimentary snacks to free weights and gear for the beach. The bed is cozy, and the sheets silky soft. The view from the terrace is lovely and peaceful. Parking is easy, and you are just a quick drive from the cafes and beaches of La Jolla. This gorgeous apartment will surpass your expectations.
Guest favourite
Guesthouse in Sherman Heights
4.86 out of 5 average rating, 144 reviews

Downtown Cottage Minutes to Gaslamp & Petco Park

AustinRating, 5 stars1 week ago
Great place to stay if you’re in town by yourself. Walkable to the convention center ~20 mins. Easy to get in and out of and quiet at night.
Guest favourite
Guesthouse in Serra Mesa
4.95 out of 5 average rating, 106 reviews

Cozy, Quiet and Private Backyard Studio Escape

JoeeRating, 5 stars2 weeks ago
I had an absolutely wonderful stay at Stephanie's place! The space was spotless and made me feel right at home. The location was fantastic and the check-in process was incredibly easy. Stephanie was an outstanding host, always quick to respond to any questions. I especially loved the rain shower! I highly recommend this Airbnb to anyone visiting San Diego and would definitely love to stay here again!
Top Guest favourite
Guesthouse in Greater North Park
4.98 out of 5 average rating, 125 reviews

New (2022) North Park Abode w/ Roof Deck

KimRating, 5 stars1 month ago
A fantastic location in North Park near Balboa Park with gorgeous views from the 2nd floor deck. It made for a gorgeous backdrop for graduation family photos! There are ample nearby restaurant choices for this safe and quiet neighborhood. Comes with a very comfortable bed, and a variety of pillows with an efficient kitchenette.. only wish the shower head streamed more water. Hosts were very gracious and responsive to our requests. I definitly plan to stay here again and have already recommended this awesome place to friends.
Superhost
Guesthouse in City Heights
4.86 out of 5 average rating, 266 reviews

Heart of SD | Zoo Nearby | Private Patio | Central

TatianaRating, 5 stars6 days ago
Was quiet but still close enough to all the activities and restaurants. Perfect for a couples getaway.
Top Guest favourite
Guesthouse in Poway
4.99 out of 5 average rating, 127 reviews

⭐️Garden studio guesthouse, resort living with pool

RonRating, 5 stars2 months ago
We stayed here Feb1-Mar31,2025 What an awesome time we had at Jeff & Andrea‘s casita. They are very gracious hosts. Absolutely gorgeous yard, so private & quiet. Spent our days touring around the area, so much to see and do in Poway. Del Mar Beach was fantastic, Shelby loved the beach. Would recommend this property for long stays. All amenities are top notch. Shopping as well as restaurants are near by. Thank you so much for having us. Ron, Arlene & Shelby
Top Guest favourite
Guesthouse in Spring Valley
4.98 out of 5 average rating, 170 reviews

Loft Cabin-Night Cinema+Hot Soaking Tub+Views!

DanielRating, 5 starstoday
My partner and I had a memorable stay at the guest house loft in spring valley. From the ride down quail canyon with the provided golf cart, to soaking in the outdoor tub, and enjoying an outdoor movie by the fire. We certainly enjoyed starting and ending our day at spring valley. Everything we set out to do was a nice 25-30 minute drive away, to beaches and museums and dining experiences, we certainly didn't mind the short trips as we were able to come back to a beautiful private canyon that the sun would hit just right as we unwind. Allison was very responsive, and all instructions very clear. We recommend this place to our friends and family, and hope to visit again sometime.

Guest house rentals with a washing machine and dryer

Guest favourite
Guesthouse in City Heights
4.98 out of 5 average rating, 135 reviews

Private Guest House for 2 with Kitchen + Laundry

ArleneRating, 5 stars1 month ago
The place was exactly as described! Paid for a place with far less amenities for the exact same price range so definitely recommend this one!
Top Guest favourite
Guesthouse in Del Cerro
4.99 out of 5 average rating, 147 reviews

The Happy Family * 2 playhouses near SDSU!

JenniferRating, 5 stars1 month ago
We loved our stay. From the beginning, Jessica was very responsive and friendly. The place was exactly as pictured. Jessica put so much thought into the small details that many other places don't think about. There was a pack and play for my almost 2 year old, but what stood out was the memory foam mattress insert and she provided tiny linens, pillow, and blankets. I've stayed at other places where they literally only had the pack and play and that was it. We were told to bring our own linens. My daughter used the toddler cot which also had linens and blankets. My kids loved the playhouses outside. They swept the outside area of any leaves every day. Pretty genius of Jessica to provide kid brooms to help keep her place clean. Now if only I can convince them to clean when we're at home! We would definitely stay again or try the larger main house if we come back.
Guest favourite
Guesthouse in Golden Hill
4.93 out of 5 average rating, 364 reviews

*BEAUTIFUL* Sunny Home in Golden Hill

TiffanieRating, 5 stars2 weeks ago
Great stay - the property was just as listed and had everything you would need for your stay. Would definitely recommend.
Superhost
Guesthouse in Lemon Grove
4.9 out of 5 average rating, 231 reviews

"Glam Farmhouse dream cottage"🏠🌠

CapsRating, 5 stars2 weeks ago
This was my second time staying here, and it was just as great as the first. The place is spacious, comfortable, and has everything I needed for a smooth and relaxing stay. It’s well-equipped and very convenient. Benito made everything simple and stress-free, as always—his hospitality is much appreciated. I’m already looking forward to coming back!
Top Guest favourite
Guesthouse in El Cajon
4.99 out of 5 average rating, 187 reviews

Modern mountain guest house. Incredible views

HollyRating, 5 stars2 weeks ago
This was a great house! The kitchen is stocked with the basics plus plenty of coffee, creamer, etc. and a basket of snacks! Water dispenser is also great. Loved everything and would absolutely stay here again and highly recommend it! Thank you Bonnie!
Guest favourite
Guesthouse in San Diego
4.93 out of 5 average rating, 150 reviews

Clean Cozy Private Guesthouse - Central San Diego

MoniqueRating, 5 stars2 weeks ago
This airbnb was very nice for two people. It was a perfect space with a spot on the driveway for one car. Walking in, the airbnb was clean and smelled really good. There was plenty of amenities and our host Frank was friendly and responsive. We would book again!
Guest favourite
Guesthouse in City Heights
4.95 out of 5 average rating, 150 reviews

Cozy Cottage 1/2 mile to North Park close to dtwn

JasonRating, 5 stars2 weeks ago
Excellent place. We loved the location relative to the sites we wanted to see. Free parking, laundry, very well stocked kitchen, comfortable bed. We were very comfortable and happy here. And as a host Wendy was phenomenal. One of the most responsive hosts I’ve had the pleasure of connecting with on Airbnb. Thank you Wendy!!!
Guest favourite
Guesthouse in Greater North Park
4.93 out of 5 average rating, 590 reviews

Quaint Craftsman#2- Walkable, Parking, EV Charging

TiffanyRating, 5 stars1 week ago
This airbnb was clean, comfy, and had a lot of great amenities available. I liked that it was in walking distance of a lot of shops and restaurants. Christina was a great host, friendly and responsive. She provided good suggestions for things to do in the area. I would recommend this listing anyone looking to stay in San Diego.

Quick stats about guesthouse rentals in La Mesa

  • Total rentals

    80 properties

  • Nightly prices starting at

    $77 AUD before taxes and fees

  • Total number of reviews

    5.2K reviews

  • Family-friendly rentals

    10 properties are a good fit for families

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with a pool

    10 properties have a pool

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