
Family-friendly holiday rentals in La Mesa
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in La Mesa
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa family-friendly rentals
Family-friendly home rentals with a hot tub

Home at the Sanctuary

Private Balcony! Sunset & SunriseVIEWS!

Comfy Mountain Top Casita

Da Hui Hut - La Mesa’s best view and spa

Charming Suite in Historic Home

The Outside Inn at The Tipsy Goat Ranch

Nature Escape•View•Sauna•SoakTub• Zoo pkg add-on

Zen Airstream Experience
Family- and pet-friendly home rentals

Insta-worthy! 1 night/many nights, no min required

Paradise View Staycation Q Bed, Sofa-bed *420 *

Clean 1BR/1BA Guest House Peaceful Private Casita

Spacious studio in La Mesa-near SDSU/Central 2 all

Retro Fun, S'mores & Smiles in Bettie Blue

Lemon Drop Cozy Studio

🤲🏼 Handmade hideaway Mt. Helix - AC/Laundry/Parking

Hacienda de las Campanas (Bell Hacienda)
Family-friendly home rentals with a pool

Mountain Retreat Ocean View-Great for Staycation

The BEST NEST Clean, peaceful, private, affordable

Sunny SD l Pool l BBQ l Pool Loungers l Sleeps 10

Former ManCave with Pool & Spa!

Bright and spacious home with views, pool & spa.

Luxury Oceanfront Condo with Unbelievable Views

Enchanted Paradise! ♨ Pool+Spa+Outdoor Kitchen ☀

San Diego family bungalow!
Quick stats about holiday rentals that are family-friendly in La Mesa
Total rentals
260 properties
Nightly prices starting at
$75 AUD before taxes and fees
Total number of reviews
11K reviews
Pet-friendly rentals
110 properties allow pets
Rentals with a pool
80 properties have a pool
Rentals with dedicated workspaces
180 properties have a dedicated workspace
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Las Vegas Holiday rentals
- Channel Islands of California Holiday rentals
- San Diego Holiday rentals
- Phoenix Holiday rentals
- Palm Springs Holiday rentals
- San Fernando Valley Holiday rentals
- Scottsdale Holiday rentals
- Henderson Holiday rentals
- Las Vegas Strip Holiday rentals
- Rentals with a hot tub La Mesa
- Pet-friendly rentals La Mesa
- Rentals with a beach view La Mesa
- Fitness-friendly rentals La Mesa
- Apartment rentals La Mesa
- Rentals with a washing machine and dryer La Mesa
- Rentals with an EV charger La Mesa
- Rentals with a patio La Mesa
- Rentals with pools La Mesa
- Guesthouse rentals La Mesa
- Smoking-friendly rentals La Mesa
- Villa rentals La Mesa
- Rentals with a fire pit La Mesa
- Rentals with outdoor seating La Mesa
- Rentals with a fireplace La Mesa
- Rentals with breakfast La Mesa
- House rentals La Mesa
- Rentals with beach access La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- SeaWorld San Diego
- Coronado Beach
- LEGOLAND California
- University of California San Diego
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Coronado Shores Beach
- Pechanga Resort Casino
- Black's Beach
- Belmont Park
- Moonlight Beach
- Sesame Place San Diego
- Liberty Station
- Law Street Beach
- USS Midway Museum
- Torrey Pines Golf Course
- Santa Monica Beach