
House holiday rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total holiday rentals
Explore 320 holiday rentals in La Mesa

Nightly prices starting at
La Mesa holiday rentals start at $44 AUD per night before taxes and fees

Verified guest reviews
Over 14,030 verified reviews to help you choose

Family-friendly holiday rentals
210 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 110 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
320 of La Mesa holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: These houses are highly rated for location, cleanliness and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

Family Pool Retreat + Gym, Fire Pits, Views (Sleep
Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can

[1,888 SF] Casa De Rosas: Spacious home near SDSU
Welcome to Casa de Rosas! Enjoy your stay at our spacious house at the front of a cul-de-sac nestled in La Mesa. Perfect for being with friends and family. Walking distance to grocery store, coffee shops, local restaurants, and bars. Our 1,888 sq. ft. home has 3 full bedrooms, 1 hybrid bedroom with trundle beds , 2 full bathrooms, den stocked with games, foosball/ pool table, couch + pull out bed, working stations, and an open main living space. Outdoor space includes seating, fire pit & grill

5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking
Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 10 guests with beautiful outdoors and garden, fire pit table, BBQ grill, FREE laundry, central A/C and heating, 5 comfortable king and queen size beds, plenty of sheets and towels, 4 large HDTVs, Netflix, Max, Hulu, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

Classic Mid-Century Mount Helix Home with Views
Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

Peaceful Casita | Firepit • Near SDSU
Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ❤ in the top-right corner to bookmark it for easy access! Minutes from key attractions: ★ 6 min to SDSU/Viejas Arena ★ 14 min to Balboa Park ★ 17 min to Downtown SD (Gaslamp) ★ 19 min to San Diego Zoo ★ 21 min to the Airport

Mountain View• Solar-heated Pool •HotTub •GameRoom
☀️Welcome to our fun, newly updated home in a quiet, secure neighborhood in La Mesa ☀️ 🌊Swim in our beautiful blue, solar-heated pool while enjoying an elevated mountain view, perfect for relaxation and fun. Unwind in our fantastic game room, equipped with a pool table, arcade machines and pop-a-hoop, offering endless entertainment for guest at all age. End the day in our in-home movie theater, where you can enjoy your favorite films in ultimate comfort. ☀️

Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

Spanish Casita w/ Hot Tub, Fire Pit, Private Yard
Welcome to Casa Stella, a beautifully renovated 1920s Spanish casita, just a 10 min drive from Balboa Park, San Diego Zoo, Downtown, and the beaches. Nestled on a quiet, picturesque street, this pet-friendly private home offers a serene stay while being just a 5-min walk to Adams Avenue's top restaurants, breweries, and yoga studios. Enjoy free parking, a cozy fire pit, and mid-century modern flair! We offer flexible check-in/ check-out, ask me how!
Popular amenities for La Mesa house rentals
House rentals with a pool

Views - Quiet Mt. Helix Home - Pool -Sleeps 11

Entertainers Dream Pool Home

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

Jamul Hacienda | Couples Retreat | Pool & Views!

San Diego Oasis: Private Pool & Sunny Escape!

Stunning 2BR/2BA| Plunge Pool, AC, Private

Modern Hilltop Home: Roomy, Views, Family-Friendly

Upscale Resort House /Views, Saltwater Pool/Spa !
Weekly house rentals

La Mesa Retreat | Hot Tub | Fire Pit | Longer stay

Sunnyside Resort Spa, Beach, Zoo, Arcade

Downtown La Mesa gem

New Townhouse | SDSU | La Mesa Village | Hikes

Family Hilltop Home w/ Views

Hot Tub, BBQ, Patio, 4 min SDSU, Central San Diego

Entire House, English garden, Private Driveway

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Private house rentals

Sunset Summit by Coastline Vacation Rentals

San Diego Airbnb Luxe: Pool, Office and Fitness

Casa Ciela•AC•Spa•15 min Downtown•Beach•Theatre

Newly Updated & Beautiful 5 bed • 3 bath • Hot Tub

Tiny Home Two w/ Garden View

Helix Haven

HotTub & 100+ Game Arcade Family Getaway San Diego

Modern Hillside Villa: 5BR, Views, Sauna & Arcade
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | June | July | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $268 AUD | $284 AUD | $310 AUD | $261 AUD | $267 AUD | $310 AUD | $363 AUD | $306 AUD | $268 AUD | $273 AUD | $284 AUD | $289 AUD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- San Diego Holiday rentals
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- Rentals with an EV charger La Mesa
- Rentals with a fireplace La Mesa
- Guesthouse rentals La Mesa
- Rentals with a hot tub La Mesa
- Rentals with pools La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals La Mesa
- Pet-friendly rentals La Mesa
- Smoking-friendly rentals La Mesa
- Fitness-friendly rentals La Mesa
- Rentals with a fire pit La Mesa
- Rentals with outdoor seating La Mesa
- Rentals with breakfast La Mesa
- Villa rentals La Mesa
- Apartment rentals La Mesa
- Rentals with beach access La Mesa
- Rentals with a patio La Mesa
- Rentals with a washing machine and dryer La Mesa
- House rentals San Diego County
- House rentals California
- House rentals United States
- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- San Diego Zoo
- Petco Park
- San Diego Convention Center E Ent
- Balboa Park
- Tijuana Beach
- Pacific Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- La Misión Beach
- Moonlight State Beach
- Las Olas Resort & Spa
- Belmont Park
- Sesame Place San Diego





