
House holiday rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total holiday rentals
Explore 320 holiday rentals in La Mesa

Nightly prices starting at
La Mesa holiday rentals start at $42 AUD per night before taxes and fees

Verified guest reviews
Over 14,030 verified reviews to help you choose

Family-friendly holiday rentals
210 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 110 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
320 of La Mesa holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: These houses are highly rated for location, cleanliness and more.

SDSU Beach Cottage
Welcome to our stunning SDSU Beach Cottage. Our home is 10 minutes away from everything amazing in San Diego! Our home is Centrally located in San Diego and in a desirable neighborhood. We are steps away from a Local favorite Eatery, Wine Bar, Beer Pub, Natural-Holistic Market, Pizza shop, Liquor Store, Nail shop, and Einstein's Bagels. Play in San Diego or stay and relax in our tropical yard that is set up to entertain you and your family with outside games and Ping Pong. 25 Yr's of age req'd
LocationFamilyHot tub

Family Pool Retreat + Gym, Fire Pits, Views (Sleep
Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can
FamilyLocationHeating

Impeccable & private: cozy KING BEDS, FUN Patio
Relax with the whole family at this peaceful home. Come relax for the evening, weekend or month in our relaxing and spacious backyard: weather you like to read, grill or sip on some wine this place has everything a family needs. We even set a small playground for your kids and grandkids to enjoy. 15 mins from downtown 17 mins from San Diego zoo / beaches 20 mins from sea world / Coronado CA 25 mins from the Mexico port of entry 40 MIN TO SAFARI ZOO / Legoland 1 hr to the desert 1.5 hrs to LA
ValueFamilyParking

2 Bed Hidden Oasis | Garden, Laundry, Parking
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!
ValueFamilyAmenities

Cozy Mid-Century Charmer | Huge Backyard | Firepit
Welcome to our renovated mid-century home in La Mesa! Perfect for family or friend getaways, this quiet retreat offers a spacious living room, full kitchen, and a huge private backyard. Enjoy shooting hoops, playing corn hole, or relaxing by the fire pit under the stars. No shared walls between bedrooms ensure added privacy and comfort. Ideal location close to San Diego’s top attractions while nestled in a peaceful neighborhood. 15 minutes drive to Downtown, Zoo, La Mesa Village & beaches
FamilyValueIndoor spaces

Classic Mid-Century Mount Helix Home with Views
Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.
ValueLocationHospitality

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!
LocationValueCheckout

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.
FamilyLocationAmenities

Peaceful Casita | Firepit • Near SDSU
Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ❤ in the top-right corner to bookmark it for easy access! Minutes from key attractions: ★ 6 min to SDSU/Viejas Arena ★ 14 min to Balboa Park ★ 17 min to Downtown SD (Gaslamp) ★ 19 min to San Diego Zoo ★ 21 min to the Airport
LocationFamilyBackyard

Mountain View• Solar-heated Pool •HotTub •GameRoom
☀️Welcome to our fun, newly updated home in a quiet, secure neighborhood in La Mesa ☀️ 🌊Swim in our beautiful blue, solar-heated pool while enjoying an elevated mountain view, perfect for relaxation and fun. Unwind in our fantastic game room, equipped with a pool table, arcade machines and pop-a-hoop, offering endless entertainment for guest at all age. End the day in our in-home movie theater, where you can enjoy your favorite films in ultimate comfort. ☀️
LocationFamilyIndoor spaces

Palm Cottage San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!
LocationValueParks

QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus
Welcome to the La Mesa Pool House! Our cozy house in La Mesa is the perfect place to relax and recharge with the family. This house is walking distance to many great La Mesa eateries such as Terra Restaurant and Surf and Soul. We are also located just 10 minutes away from San Diego State University and we are less than 20 minutes from all major attractions in San Diego: downtown, Little Italy, Zoo, Sea World, beaches and more!
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Popular amenities for La Mesa house rentals
House rentals with a pool

Bright Contemporary 5-Bedroom Oasis, Pool and Yard
LocationValueView

The Queen House
ValueLocationAccess

Entertainers Dream Pool Home
ValueLocationParking

San Diego Pool | Fire Pit | Sunshine | Sleeps 10
ValueLocationBathroom

Surf Cottage w/Pool & Firepit 10min from the beach
LocationValuePets

Jamul Hacienda | Couples Retreat | Pool & Views!
FamilyValuePets

San Diego Oasis: Private Pool & Sunny Escape!
LocationValuePool

Bright and spacious home with views, pool & spa.
FamilyLocationHot tub
Weekly house rentals

Cozy 4bd Family Home near all SD Attractions!
FamilyValueBreakfast

Discover La Mesa: Your Perfect Cozy Base
LocationValueComfort

The Glass House - A Nature Retreat
FamilyLocationLayout

Sunnyside Resort Spa, Beach, Zoo, Arcade
FamilyLocationCondition

Downtown La Mesa gem
FamilyLocationQuiet

Beautiful Mid-Century Home on Tree Lined Street!
LocationFamilyAir conditioning

New Townhouse | SDSU | La Mesa Village | Hikes
LocationComfortLayout

Glass Home with Views, Hot Tub, FREE EV Charging!
ValueLocationCheck-in
Private house rentals

Tiny Home with a View
LocationValueHot tub

Vintage Vibes|King Bed|Big Screen|Backyard & Bunks
FamilyLocationLaundry

Amazing Views - Central Location & Close to SDSU
FamilyLocationSleep quality

Lavish pool Villa In Mt. Helix, close to beaches
ValueFamilyCheck-in

The Sanctuary
FamilyLocationHospitality

La Mesa Retreat | Hot Tub | Fire Pit | Longer stay
FamilyLocationQuiet

HotTub & 100+ Game Arcade Family Getaway San Diego
LocationValueHot tub

Family Hilltop Home w/ Views
LocationFamilyHospitality
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | June | July | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $262 AUD | $277 AUD | $303 AUD | $255 AUD | $260 AUD | $303 AUD | $354 AUD | $299 AUD | $262 AUD | $266 AUD | $277 AUD | $282 AUD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- San Diego Holiday rentals
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- Villa rentals La Mesa
- Rentals with an EV charger La Mesa
- Guesthouse rentals La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals La Mesa
- Pet-friendly rentals La Mesa
- Rentals with a hot tub La Mesa
- Smoking-friendly rentals La Mesa
- Rentals with a fireplace La Mesa
- Rentals with a fire pit La Mesa
- Rentals with outdoor seating La Mesa
- Rentals with a patio La Mesa
- Rentals with pools La Mesa
- Rentals with breakfast La Mesa
- Rentals with beach access La Mesa
- Fitness-friendly rentals La Mesa
- Apartment rentals La Mesa
- Rentals with a washing machine and dryer La Mesa
- House rentals San Diego County
- House rentals California
- House rentals United States
- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- San Diego Zoo
- San Diego Convention Center E Ent
- Petco Park
- Balboa Park
- Tijuana Beach
- Pacific Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Ocean Front Walk
- La Misión Beach
- Mission Beach
- Las Olas Resort & Spa
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego





