Family-friendly holiday houses in James Island
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in James Island
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for James Island family-friendly rentals
Family-friendly home rentals with a hot tub
Home in Charleston
4.87 out of 5 average rating, 206 reviewsCharleston Tranquil Marshside Retreat w/Pool/Spa
Home in Charleston
4.84 out of 5 average rating, 430 reviewsBest of Both Worlds with Beautiful Back-Yard Oasis
Home in North Charleston
4.97 out of 5 average rating, 251 reviewsHome The On Hill - Near Everything Charleston!
Cottage in Isle of Palms
4.96 out of 5 average rating, 108 reviewsCharming Cottage at Beach with Golf Cart
Island in Isle of Palms
4.85 out of 5 average rating, 183 reviewsSummer Hayes on IOP with extra special Pool
Townhouse in Folly Beach
4.87 out of 5 average rating, 76 reviews121 E Ashley - The Blue Crab - Renovated in 2024
Bungalow in Isle of Palms
4.93 out of 5 average rating, 27 reviews4 BedroomBungalow with Huge Private Pool
Home in Folly Beach
4.8 out of 5 average rating, 30 reviewsPool, Hot Tub, Marsh, Ocean and Lighthouse Views!
Family- and pet-friendly home rentals
Guest suite in Charleston
4.92 out of 5 average rating, 340 reviewsIsland Hideout
Home in Charleston
4.86 out of 5 average rating, 273 reviewsCentral Island Home
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 214 reviewsBungalow Under The Oaks
Guest suite in Mount Pleasant
4.9 out of 5 average rating, 311 reviewsCathy’s Conch House. Pets welcome
Cottage in Johns Island
4.9 out of 5 average rating, 205 reviewsLi'l Blue Cottage - NO PET FEE!
Home in Charleston
4.8 out of 5 average rating, 416 reviewsCharming 1BD with parking!
Condo in Charleston
4.83 out of 5 average rating, 111 reviewsCenter of French Quarter w Free Parking!
Home in Charleston
4.98 out of 5 average rating, 101 reviewsThe Rutledge- A Charleston Escape
Family-friendly home rentals with a pool
Condo in Charleston
4.93 out of 5 average rating, 109 reviewsFolly Beach sunrise and sunsets
Apartment in Johns Island
4.95 out of 5 average rating, 204 reviewsSailors Rest: Heated Pool & Sauna, Johns Island
Cottage in Mount Pleasant
4.96 out of 5 average rating, 348 reviewsWalk to Shem Creek! & Bike to BEACH
Townhouse in Folly Beach
4.79 out of 5 average rating, 107 reviews118 Waters Edge~ River View~ 3bd/3ba~ Pool
Guesthouse in Charleston
4.84 out of 5 average rating, 111 reviewsRomantic Beach Style Cottage close to everything!
Apartment in Charleston
4.78 out of 5 average rating, 451 reviewsCourtyard Suite with Tranquil Garden & Heated Pool
Apartment in Folly Beach
4.96 out of 5 average rating, 350 reviewsWater life “Aquavida”
Cottage in Mount Pleasant
4.96 out of 5 average rating, 134 reviewsBreezy Poolhouse Cottage
Destinations to explore
- Savannah Holiday rentals
- Hilton Head Island Accommodation & holiday rentals
- Kiawah Island Holiday rentals
- Tybee Island Accommodation & holiday rentals
- Folly Beach Accommodation & holiday rentals
- Surfside Beach Accommodation & holiday rentals
- Mount Pleasant Accommodation & holiday rentals
- Hilton Head Accommodation & holiday rentals
- Beaufort Holiday rentals
- Atlanta Accommodation & holiday rentals
- Charleston Holiday rentals
- Myrtle Beach Accommodation & holiday rentals
- Family-friendly rentals United States
- Family-friendly rentals Myrtle Beach
- Family-friendly rentals Charleston
- Family-friendly rentals Savannah
- Family-friendly rentals South Carolina
- Smoking-friendly rentals James Island
- Rentals with breakfast James Island
- Kid-friendly rentals James Island
- Private suite rentals James Island
- House rentals James Island
- Townhouse rentals James Island
- Condo rentals James Island
- Rentals with a fire pit James Island
- Rentals with an EV charger James Island
- Pet-friendly rentals James Island
- Waterfront rentals James Island
- Fitness-friendly rentals James Island
- Rentals with beach access James Island
- Rentals with a hot tub James Island
- Rentals with outdoor seating James Island
- Rentals with a washing machine and dryer James Island
- Rentals with pools James Island
- Rentals with a kayak James Island
- Apartment rentals James Island
- Villa rentals James Island
- Rentals with a patio James Island
- Guesthouse rentals James Island
- Rentals with a fireplace James Island
- Monthly Rentals James Island
- Beachfront rentals James Island
- Bed and breakfasts James Island
- Rentals with lake access James Island
- Family-friendly rentals Charleston County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom