
House holiday rentals in Upstate South Carolina
Find and book unique houses on Airbnb
Top-rated house rentals in Upstate South Carolina
Guests agree: These houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina house rentals
House rentals with a pool

Lakeside Family & Dog Retreat Awaits! DWC

POOL open til Oct 12 HOT TUB Sleeps 11 Gameroom

Pet + Family Friendly 4BR Pool House Near Furman

Wonderful mountain cottage with amazing view!

Shalom House with Pool near DT Greer SC

A quiet place in the country

Greenville Bungalow w/ Stock Tank Pool + Fire pit

Saluda Splash Home
Weekly house rentals

3 Min to Downtown, Game Room, King bed

900' of lake front property - 20 min from Clemson

The Mountain House

Grace Mountain Cottage-Mtn views /Peaceful+Private

Kargohaus ~ Unique Shipping Container - Dog Park!

The Wright Place! 25/min DT G-Ville. Pool/Hottub.

Welcome to River House

Mountain Villa 15min from Downtown Greenville
Private house rentals

Lakefront Getaway: Fire Pit ~ Dock ~ Games!

Palmetto Trailside Retreat

The Hideaway

Broadview A Highlands Mountain Top Retreat

Pool, Pickleball, Poker, Ping-Pong! King beds!

House 564

Glimpse of GVL

Sunset Cottage -Waterfront with Kayaks
Destinations to explore
- Western North Carolina Holiday rentals
- Nashville Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Gatlinburg Holiday rentals
- Charleston Holiday rentals
- Charlotte Holiday rentals
- Pigeon Forge Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Asheville Holiday rentals
- North Myrtle Beach Holiday rentals
- Rentals with beach access Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with a home theatre Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Condo rentals Upstate South Carolina
- Resort rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Ski-in/ski-out rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Rentals with a fire pit Upstate South Carolina
- Villa rentals Upstate South Carolina
- Tree house rentals Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Tent rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Rentals with a washing machine and dryer Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Holiday home rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Boutique hotel rentals Upstate South Carolina
- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- Gorges State Park
- Table Rock State Park
- The North Carolina Arboretum
- Chimney Rock State Park
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Saint Paul Mountain Vineyards
- City Scape Winery
- Burntshirt Vineyards
- Overmountain Vineyards
- Russian Chapel Hills Winery
- Wellborn Winery