
Boutique hotel holiday rentals in Upstate South Carolina
Find and book unique boutique hotel rentals on Airbnb
Top-Rated Boutique Hotels in Upstate South Carolina
Guests agree: These boutique hotel rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina Boutique Hotels
Family-Friendly Boutique Hotels

River Edge Inn Family Suite with Full Kitchen

Luxurious Villa with a Fireplace and Balcony

River Edge Inn Family Suite with Kitchenette

ADA Premium King Room | New Boutique Hotel: The Ti

*New* Boutique Hotel - Double Queen Suite

Queen Suite | New Boutique Hotel: The Timber

*New* Boutique Hotel - Premium King Room

Premium Double King Suite | New Boutique Hotel
Boutique Hotels with a patio

Brookstone Lodge Boutique Hotel Near City Center

Charming 1 bedroom with private bathroom

Double Queen Rm: Near DT Hendo & Flat Rock

Boutique Hotel: Rudisill Suite : Passport 2 Luxury

Biltmore Hideaway Villa
Other boutique hotel holiday rentals

Elevation Lofts Boutique Hotel - Unit 304

Mountain Aire Cottages & Inn - The Dogwood Room

Brookstone Lodge Asheville Biltmore Village Area

Brookstone Lodge an Choice Ascend Collection Hotel

Rudyard Kipling Suite By The Lake

Elevation Lofts Boutique Hotel - Unit 301

Elizabeth Barrett Suite By The Lake

Lord Tennyson Penthouse Suite By The Lake
Destinations to explore
- Western North Carolina Holiday rentals
- Nashville Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Pigeon Forge Holiday rentals
- Cape Fear River Holiday rentals
- North Myrtle Beach Holiday rentals
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Villa rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Rentals with a fire pit Upstate South Carolina
- Rentals with a washing machine and dryer Upstate South Carolina
- House rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Condo rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Holiday home rentals Upstate South Carolina
- Resort rentals Upstate South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Rentals with a home theatre Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Tree house rentals Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Boutique hotel rentals United States
- Blue Ridge Parkway
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Saint Paul Mountain Vineyards
- Overmountain Vineyards
- Burntshirt Vineyards
- City Scape Winery
- Wellborn Winery
- Russian Chapel Hills Winery