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House holiday rentals in San Carlos Island

Find and book unique houses on Airbnb

Top-rated house rentals in San Carlos Island

Guests agree: These houses are highly rated for location, cleanliness and more.

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Top Guest favourite
The screened-in pool area features a serene swimming pool with shimmering water, two blue lounge chairs positioned nearby, and views of a wide canal. A thatched-roof Tiki hut can be seen across the water, surrounded by lush greenery.
Home in Cape Coral
4.99 out of 5 average rating, 254 reviews

LUX Villa w/ Private Salt Water Pool, Lanai, Canal

Are you looking to swim, relax outdoors, fish and take in beautiful sunsets on a wide gulf access canal? If so you will fall in love with this stunning newly constructed custom built home! The 2750 square foot home is bright & airy with two main bedroom on-suites & a separate family wing! The gourmet kitchen, dining room & great room open via large sliders to the lanai & pool w/ views of the canal in much desired SW Cape! Beach inspired villa! Large captains walk & Tiki! Check out our reviews!

Top Guest favourite
A sunlit pool area is framed by palm trees, with views of the canal and neighboring homes in the background. Comfortable loungers are positioned along the poolside, inviting relaxation amidst the tranquil waterfront setting.
Home in Fort Myers Beach
4.99 out of 5 average rating, 112 reviews

Paradise on canal minutes to Ft Myers Beach/Gulf

Beautiful 3 Bedroom, 3 bath home on a canal with a dock! Bring your boat or jet skis! Enjoy a relaxing stay watching the dolphins and manatee right off the dock. This exquisitely updated home has everything you need for a fantastic vacation. Especially location! 5 minutes to Ft Meyers Beach. Enjoy the resort right in your own backyard. New pool with hot tub and sun shelf. Enjoy beautiful sunsets off the huge patio. Trolly to beach at neighborhood entrance or walk to in minutes.

Guest favourite
Home in Cape Coral
4.92 out of 5 average rating, 13 reviews

Luxury Waterfront Escape - Private Pool & Jacuzzi

Managed by a small team as a family business, you will get the VIP treatment. Heated pool and jacuzzi all year. Gulf access. Boat dock. Escape to a luxury lakefront retreat in Cape Coral with direct Gulf access! Relax by the pool, entertain in the outdoor kitchen with TV lounge, or dock your boat right at the private dock. Inside, enjoy a chef’s kitchen, modern open living, and a dedicated office. Perfect for upscale travelers seeking comfort, style, and waterfront adventure.

Guest favourite
Home in Fort Myers Beach
4.93 out of 5 average rating, 14 reviews

“Welcome to Relax and Unwind".

“Welcome to Relax and Unwind, your perfect waterfront getaway in beautiful Fort Myers Beach. This charming 2-bedroom, 2-bath home at 70 Emily Lane offers everything you need for comfort and relaxation — a queen bed, twin beds, a cozy futon, and a fully equipped kitchen. Enjoy peaceful mornings by the water, take a kayak or bike ride. Just minutes from the beach and top attractions like Margaritaville Resort, the Key West Ferry, the vibrant marina, and local restaurants

Top Guest favourite
An expansive open kitchen and dining area showcases sleek white cabinetry and a large kitchen island. Wooden barstools provide seating at the island, while contemporary lighting fixtures hang above. Large windows enhance the airy atmosphere, revealing a modern living space in the background.
Home in Fort Myers
4.99 out of 5 average rating, 99 reviews

Modern City Loft in Downtown River District

Welcome to Gun-Loft, a custom-designed modern sanctuary in the Downtown River District. This expansive 3500 square foot city loft is tailored for those seeking to embrace the cosmopolitan lifestyle, with the perfect blend of urban luxury and cultural richness. Whether it's a leisurely stroll to the Edison Ford Home, an exciting night out, or a culinary adventure in the restaurants nearby, Gun-Loft offers an unparalleled experience in the city's most coveted location.

Top Guest favourite
A coastal home featuring a light blue exterior with a metal roof, surrounded by palm trees. The front yard is landscaped with greenery, and a paved driveway leads to a covered parking area beneath the house. Steps ascend to a front porch adorned with white railings.
Home in Fort Myers Beach
5 out of 5 average rating, 29 reviews

Beach Bound + 2025 Build + Walk to town

Personally hosted by Paul & Alicia of Dancing Palms Vacations, a fresh coastal escape with all the essentials: a saltwater heated pool, fenced backyard, and spacious lanai for lounging or dining outdoors. The covered front porch frames bay views and catches Gulf breezes — perfect for slow mornings with coffee. After the beach (just a short walk away), fire up the Blackstone grill or wander to local restaurants and bars. (FMB permit/license 25-0052)

Top Guest favourite
The exterior of Captain Jack’s Cottage is displayed, featuring a light-colored wooden structure with a spacious patio. Colorful adirondack chairs are arranged around the outdoor area, with a calming sunset in the background. A staircase leads to the upper level, enhancing accessibility.
Home in Fort Myers Beach
4.97 out of 5 average rating, 30 reviews

Cap't Jack's Waterfront Cottage

Escape to Captain Jack’s Cottage, a newly renovated canal-front retreat perfect for up to 4 guests. Just a 10-15 minute walk to the sandy beach, this charming home offers a tranquil vibe with modern amenities, a private patio, and stunning water views. Walk to local restaurants or hop on the nearby beach trolley. Whether relaxing or seeking adventure, Captain Jack’s Cottage is ideal for a memorable coastal getaway. Book now and unwind in paradise!

Top Guest favourite
Home in Fort Myers Beach
5 out of 5 average rating, 18 reviews

Icon on the bay - Panoramic views/Rooftop hot tub

Waterfront fun meets luxury in this 3-story Fort Myers Beach home on San Carlos Island! Featuring 4 bedrooms, bay-view living room with balcony, and a full kitchen & dining on the 2nd floor. Enjoy an outdoor kitchen with grill and bar, plus pool table, ping pong & air hockey. Private dock with boat lift and a rooftop deck with turf, lounge chairs & a 6-person hot tub for sunset soaking. Perfect for families, boaters & group getaways.

Top Guest favourite
Home in Cape Coral
5 out of 5 average rating, 7 reviews

Waterfront with Saltwater Pool, Sauna, Cold Plunge

Experience the epitome of comfort and luxury in our exquisite 4-bedroom, 4-bathroom waterfront wellness retreat. Revel in the tranquillity of water views and be pampered by a host of rejuvenating amenities, including a therapeutic saltwater pool, a soothing sauna, and a refreshing cold plunge. This sanctuary is designed with top-of-the-line features and sumptuous interiors that ensure a restful and revitalizing stay beyond compare.

Superhost
Home in Cape Coral
4.5 out of 5 average rating, 4 reviews

Sunset Escape | Heated Pool | Amazing Lake Views

PELICAN SUNSET RETREAT • Spectacular lakefront sunsets • Heated pool year-round • Game room with pool table & ping pong • Fitness area & workout equipment • Smart TVs in every bedroom • Outdoor dining & BBQ area • Fast WiFi • Family-friendly home for up to 10 guests • About 8 min to Cape Coral Marina • About 12 min to Yacht Club Beach The perfect Florida getaway for families and groups! ugar único tiene su propio estilo.

Superhost
Home in Fort Myers Beach
4.6 out of 5 average rating, 5 reviews

Ostego Charm | Fort Myers Beach Coastal Charm

Welcome to Ostego Charm! This beautiful 2 bed, 2 bath Fort Myers Beach home offers an open floor concept filled with natural light and coastal charm. Enjoy breezy evenings on the spacious covered porch or entertain in the bright, modern living space. Elevated for safety and style, and surrounded by lush tropical landscaping, Ostego Charm is just minutes from the beach—your perfect island getaway or vacation rental!

Top Guest favourite
Aerial view captures a vibrant coastal community with a variety of homes, and a canal running alongside. The property highlights a private pool, spacious lanais, and proximity to the water, while streets lined with palm trees and nearby buildings suggest a lively beach atmosphere.
Home in Fort Myers Beach
5 out of 5 average rating, 36 reviews

Primo Paradise

LOCATION is everything! Your family will enjoy easy access to everything from this centrally located property. Walkable to Time Square, the beach, and so much more! Brand new Margaritaville is .2/mile walk. Lani Kai is .3/mile. While at the property you will become obsessed with the pool, canal view, and lanais! This home offers it all! Primo Paradise is also big enough to bring the whole family!

Popular amenities for San Carlos Island house rentals

  1. Airbnb
  2. United States
  3. Florida
  4. Lee County
  5. San Carlos Island
  6. House rentals