
House holiday rentals in Panama
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Top-rated house rentals in Panama
Guests agree: These houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool

Luxury beachfront villa!

Mountain Retreat: Peaceful & Private Escape

BirdHouse@ Gamboa Panamá Canal

Poolside Paradise in Santa Clara

Spacious Vacation Home in a Tourist Area

3 min to Pedasi, 5 min to the Beach, Private Pool!

Modern, Peaceful Torio Treasure

Beach Villa in Coronado.
Weekly house rentals

Family home in Gamboa next to the Canal

Wow House - Central Boquete!

Private Mountain Escape El Valle

The Hidden Gem

Comfortable, modern house - breathtaking sea view

Casa Bonita at Hermosa Bay, Chiriqui.

Amazing Overwater Villa in Basti

Spectacular Beachfront House
Private house rentals

Altos del Maria: Portazul - a Mountain Retreat

PIPA BEACH | Oceanfront with Beach Access

The Bird's Nest in the Clouds

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa

Casa Blanca- Ocean view, couples & family friendly

Cabana Vergara Santa Fe

The Pool House, Beach House on Paunch Beach

NEW! Luxury Home in 5-Star Resort | King | Garden
Destinations to explore
- Beach house rentals Panama
- Boat rentals Panama
- Rentals with an accessible height bed Panama
- Rentals with a patio Panama
- Bungalow rentals Panama
- Fitness-friendly rentals Panama
- Villa rentals Panama
- Condo rentals Panama
- Rentals with lake access Panama
- Hotel rentals Panama
- Rentals with beach access Panama
- Kid-friendly rentals Panama
- Bed and breakfasts Panama
- Family-friendly rentals Panama
- Smoking-friendly rentals Panama
- Rentals with a fire pit Panama
- Lakehouse rentals Panama
- Rentals with a hot tub Panama
- Boutique hotel rentals Panama
- Tiny house rentals Panama
- Chalet rentals Panama
- Rentals with a home theatre Panama
- Island rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with a fireplace Panama
- Apartment rentals Panama
- Tree house rentals Panama
- Rentals with breakfast Panama
- Pet-friendly rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Waterfront rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Guesthouse rentals Panama
- Rentals with a washing machine and dryer Panama
- Rentals with pools Panama
- Farmstay rentals Panama
- Townhouse rentals Panama
- Loft rentals Panama
- Rentals with a sauna Panama
- Nature eco lodge rentals Panama
- Cottage rentals Panama
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