Boutique hotels in Panama

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Panama

Guests agree: These boutique hotels are highly rated for location, cleanliness and more.

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Superhost

A furnished bedroom features a spacious bed with white linens, flanked by bedside tables with lamps. Soft artwork adorns the wall above, while a bench rests at the foot of the bed. A cozy throw drapes over the bench, completing the inviting arrangement.

Hotel room in Boquete

4.89 out of 5 average rating, 117 reviews

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

LocationValueBathroom

Superhost

A spacious bed is positioned centrally in the room, adorned with neutral-toned bedding. Two ottoman-like stools are placed at the foot of the bed. A laptop is being used on the bed, with soft lighting emanating from lamps on either side, creating a cozy ambiance.

Hotel room in San Carlos

4.78 out of 5 average rating, 141 reviews

Surf, Beach & Relax Boutique Stay I Manglar Lodge

Manglar Lodge is a relaxed boutique beach stay in the surf town of El Palmar, San Carlos, on Panama’s Pacific coast. Surrounded by tropical gardens, it’s the perfect place to unwind and enjoy the laid-back beach vibe. This king room includes Wi-Fi, A/C, cable TV, private bathroom, mini fridge, microwave, coffee maker, and a cozy atmosphere for a comfortable stay. Just a short walk to the beach, surf spots, restaurants, and local cafés. **Upper floor room, stairs required. **No pets allowed.

FamilyLocationGetting around

Superhost

A spacious living area is highlighted by wooden ceilings and large windows that capture sea views. Two comfortable seating areas with wicker furniture are arranged around a central table. A vibrant artwork adorns one wall, while a doorway leads to a private bedroom.

Hotel room in Isla Colon

4.71 out of 5 average rating, 7 reviews

Hotel Palma Royale - Penthouse - 2 bedroom

2 bedroom Penthouse suite with full kitchen and refrigerator/freezer and spacious living area a with two queen size beds, wrap around balcony with breathtaking sea views, 2 bathrooms with rain water showers, office desk, air conditioning, coffee pot with grinder and panamanian coffee beans, flat screen tv with cable, top floor, free wifi, large quality windows and doors, pillow top mattresses, marble or coral tile, non-smoking rooms, beach towels, blow dryers, laundry service, board games.

LocationFamilyCleanliness

Top Guest favourite

The bungalow features a screened-in porch, framed by lush greenery and colorful plants. Warm sunlight casts shadows across the wooden structure, creating a serene and inviting atmosphere amidst the surrounding foliage.

Hotel room in Bastimentos Island

4.96 out of 5 average rating, 70 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A stand alone studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. We have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

LocationFamilyGetting around

Guest favourite

The room features two spacious beds with modern wooden frames. A wooden bench runs along the foot of one bed. A large area rug adds a pop of color to the floor. Soft lighting complements the earthy tones of the walls.

Hotel room in Playa Venao

5 out of 5 average rating, 17 reviews

Brisa - Ocean Views, Calm Vibes, King/Twin beds

Brisa is the perfect family room on the ground floor, made for relaxing after a fun day in the sun. Equipped with a mini fridge, AC, TV (ready for you to sign into all your online viewing accounts), hot/cold water and beautiful breezy covered seating area outside with ocean views. Steps from our pool! *Additional guest, available to kids up to 12 year old* *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host. *

LocationFamilyView

Superhost

Hotel room in Panamá

Duplex Room Hotel Bardot Boutique

Bienvenido a Hotel Bardot Boutique, donde el lujo clásico y el diseño sofisticado se fusionan en el corazón del Casco Antiguo. Nuestra encantadora habitación de 50 m² ha sido concebida para ofrecer una experiencia íntima y acogedora para dos personas. Destaca por su cuidada estética, detalles arquitectónicos únicos y una atmósfera cálida que invita al descanso, creando un ambiente con carácter que eleva cada momento de la estancia.

LocationHospitalityCleanliness

Guest favourite

A large swimming pool is surrounded by tropical greenery, featuring serene blue water reflecting the sky. Sun loungers and umbrellas are positioned around the pool, providing relaxation areas. The space is complemented by a rustic structure with a thatched roof in the background.

Hotel room in Playa coronado

4.91 out of 5 average rating, 35 reviews

Walk to the Pacific Ocean | Pool | Adults Only

Wecome to Casa Swell ! Wake up in a peaceful tropical retreat just minutes from Playa Coronado Beach and the Pacific Ocean. Surrounded by palm trees and natural light, this private room is part of a charming adults-only boutique hotel (ages 13+), perfect for couples, solo travelers, and remote workers seeking comfort and relaxation. Enjoy the pool, lush tropical gardens, and the laid-back atmosphere of Casa Swell.

LocationValueBarbecue

Guest favourite

A charming stone structure is surrounded by lush greenery in this tranquil setting. Soft lighting enhances the architectural details, while the inviting garden area features neatly trimmed hedges and flower beds. A patio area can be seen beside the main building, perfect for outdoor relaxation.

Hotel room in El Valle de Antón

4.84 out of 5 average rating, 50 reviews

Medieval Suite Nature & Art

La Corte del Re is a tourist structure composed of a set of suites with a medieval theme (macabre art) immersed in the woods where art and nature merge in the heart of Anton's Valley. A few steps from the center are equipped with all comforts and have a park, pool, lake with Koi carpe and parking. They do not have a kitchen. Guests can take advantage of a Muay Thai, jiu-jitsu and MMA academy.

LocationValueOutdoor spaces

Guest favourite

A wooden plaque with the name 'Andy 1' is displayed prominently. The name is painted in black cursive lettering on a light wood background. A few elegant cream-colored flowers are attached to the top corner of the plaque, adding a decorative touch.

Hotel room in Punta Chame

4.89 out of 5 average rating, 9 reviews

Andy 1, room in a house with beach access

The Andy 1 room is located on a mezzanine accessed by stairs from the first floor of the houseboat. The room sleeps three people, has a queen bed and a single bed. It has its own private bathroom in the room, a desk, a television, and has air conditioning and internet access. Guests in this room have access to a kitchen located within the lot, a short distance from the houseboat.

FamilyValueBreakfast

Superhost

A bright blue room features a queen bed with a patterned bedspread and two pillows. A small wooden table and chair are visible, while colorful fish art adorns the walls. A door leads to the bathroom, and a window allows natural light into the space.

Hotel room in Las Tablas Abajo

4.81 out of 5 average rating, 89 reviews

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.

ValueLocationCheck-in

Guest favourite

The exterior features a warm yellow facade with a large arched window and distinct wooden door, complemented by a neatly landscaped flower bed. Paved pathways lead to the entrance, providing a welcoming approach to the boutique hostel.

Hotel room in Panamá

4.88 out of 5 average rating, 24 reviews

Entire place Sofia's B&B Hostal Boutique

Boutique hostel accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. You can make use of the well-equipped kitchen, comfortable living room and dining room. We have a washer and dryer at your disposal for an additional cost.

LocationValueAir conditioning

Top Guest favourite

Hotel room in Panamá

5 out of 5 average rating, 14 reviews

The Corner Suite #110 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 35–37 m² suite features a king-size bed, full kitchen, washer/dryer, Coffe machine, and A/C — designed with thoughtful touches to make you feel at home.

ValueLocationNearby