
Guesthouse holiday rentals in Mission Bay, San Diego
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Top-rated Guesthouses in Mission Bay, San Diego
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Mission Bay, San Diego guesthouses
Family-Friendly guesthouses

Adorable San Diego Guesthouse

Poolside Ocean View Studio

Fig Tree Bungalow

Pacific Beach Guest House With Garage and A/C

The BEST NEST Clean, peaceful, private, affordable

Cosy quiet Guesthouse near SDSU

Charming North Park Cottage

Family friendly 2BR casita w/AC & rooftop Igloo
Guesthouses with a patio

Adorable cottage in Talmadge

Private 1 BR Paradise retreat

La Jolla Oasis: Ocean, City and Fire Works Views

New! Beautiful Private Casita- King Bed & Office

Cozy, Quiet and Private Backyard Studio Escape

Casita with private yard and separate entrance

New (2022) North Park Abode w/ Roof Deck

Violet Oasis | hot tub, kitchen, no dog fee!
Guest house rentals with a washing machine and dryer

Beautiful Private Villa walk to beach

Carrie’s North Park Casita, in Heart of San Diego
*BEAUTIFUL* Sunny Home in Golden Hill

San Diego Shangri La

Law Street Retreat

Indoor/Outdoor Sanctuary in Ocean Beach

Mt Helix Studio Loft with Mountain Views

Beautiful Historic Home and Gardens Near Downtown!
Quick stats about guesthouse rentals in Mission Bay, San Diego
Total rentals
20 properties
Nightly prices starting at
$187 AUD before taxes and fees
Total number of reviews
2.8K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wi-Fi availability
20 properties include access to Wi-Fi
Popular amenities
Kitchen, Wi-Fi and Pool
Destinations to explore
- Rentals with a fire pit Mission Bay
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- Rentals with a sauna Mission Bay
- Smoking-friendly rentals Mission Bay
- Beach house rentals Mission Bay
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- House rentals Mission Bay
- Beachfront rentals Mission Bay
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- Pet-friendly rentals Mission Bay
- Condo rentals Mission Bay
- Kid-friendly rentals Mission Bay
- Townhouse rentals Mission Bay
- Rentals with breakfast Mission Bay
- Rentals with a fireplace Mission Bay
- Rentals with lake access Mission Bay
- Waterfront rentals Mission Bay
- Hotel rentals Mission Bay
- Rentals with a patio Mission Bay
- Cottage rentals Mission Bay
- Rentals with an EV charger Mission Bay
- Fitness-friendly rentals Mission Bay
- Family-friendly rentals Mission Bay
- Apartment rentals Mission Bay
- Rentals with pools Mission Bay
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- Rosarito Beach
- Oceanside City Beach
- Tijuana Beach
- Torrey Pines State Beach
- Pacific Beach
- Coronado Beach
- San Clemente State Beach
- Coronado Shores Beach
- Oceanside Harbor
- San Onofre Beach
- SeaWorld San Diego
- South Coronado Beach
- Black's Beach
- Windansea Beach
- Trestles Beach
- Surf Beach
- University of California San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- Balboa Park
- Playas Los Buenos
- Belmont Park
- Pechanga Resort Casino
- Liberty Station