Guesthouse holiday rentals in San Diego

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in San Diego

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite
A modern living area features a spacious sectional sofa with decorative pillows, accompanied by a marble top coffee table. A bright kitchenette is visible, equipped with stainless steel appliances. Natural light streams through multiple windows, leading to an outdoor space with a view.
Guesthouse in Bay Park
4.97 out of 5 average rating, 377 reviews

Private Guesthouse with Bay View Deck

The one bedroom, one bath unit was recently remodeled (in 2017) and includes all new kitchen, bathroom, full size laundry and air conditioning. The large 400 square foot private deck has new outdoor furniture with views of Mission Bay and gorgeous sunsets year round. Enjoy a show on the 50" 4K LG smart TV in the living room which offers Netflix, Amazon Video, and major network TV stations. Cook a delicious meal in the kitchenette complete with a mini-fridge/freezer, microwave, electric stove top, coffeemaker, and more. If you plan to head to the beach, the storage ottoman is secretly a "beach box" containing a couple of folding chairs, beach toys, towels and a small cooler. The unit is stocked with coffee, shampoo, conditioner, laundry supplies, iron, and more. Filtered water is provided via a faucet on the kitchen sink. Easy check-in via a numeric keypad on the front door with the code provided prior to arrival. Plenty of street parking is available. We love meeting new people and live next door in the main house so we are available most anytime. We are both from San Diego and still love to explore the latest new spots so we are happy to give recommendations. Bay Park is a great central neighborhood originally built in the early 1940s. It was recently voted the most livable neighborhood in a recent San Diego poll. Check out the restaurants on Morena Boulevard, which are just a few minutes' walk away or explore all of the major attractions of San Diego easily. The house has easy access to I-5 and is only 10-15 mins from downtown, Sea World, the San Diego Zoo and the airport. The private guest house is located across from Mission Bay and within walking distance to bay, market, restaurants and coffee shops. Uber/Lyft is $8 to $14 to most of San Diego's main attractions. There is a bit of white noise from the highway down the hill near Mission Bay when out on the deck but nothing too bad, just worthy of mention. The unit has double paned vinyl windows so it's quiet indoors.

Top Guest favourite
A curving staircase is visible, flanked by white walls and adorned with vibrant blue tiles. Handrails provide support along the ascent, leading to a bright upper space. A potted plant enhances the serene ambiance at the top of the stairs.
Guesthouse in Mission Hills
5 out of 5 average rating, 223 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina.  With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

Guest favourite
A scenic view captures lush hillsides and a calm lake under a clear sky, with a rainbow arching gracefully over the landscape. Green vegetation sprawls across the area, adding vibrancy to the tranquil scene.
Guesthouse in Escondido
4.91 out of 5 average rating, 813 reviews

Hilltop cabin retreat with lake & mountain views

Rustic hilltop cabin overlooking Lake Hodges. Surrounded by open canyons & mountains, you will feel like you're a million miles away from everything as you take in the views from the cabin, deck or the outside shower, swim in the saltwater pool, or relax by the fire bowl. A short walk to lake with boating, fishing & miles of hiking/mountain biking trails. Property offers swimming pool, fire bowl, and shaded arbor. SD Zoo Safari Park, wineries, breweries, & ocean beaches all within easy reach.

Guest favourite
The exterior of a historic stone cottage showcases a rounded structure with large, circular windows. Native plants and decorative rocks surround the entrance, highlighting the natural landscape. The name 'Anna' is displayed on a rustic wooden sign, further enhancing the cottage's character.
Guesthouse in La Mesa
4.89 out of 5 average rating, 403 reviews

Anna's Historic Stone Cottage w/panoramic View!

Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!

Top Guest favourite
A serene koi pond is surrounded by lush greenery and illuminated by soft lights, creating a calming atmosphere. The water reflects the vibrant colors of the koi fish and the gentle flow of nearby waterfalls, enhancing the tranquil setting of the outdoor space.
Guesthouse in Hillcrest
5 out of 5 average rating, 541 reviews

Waterhaven - A Pondside Oasis

Please read house rules before booking. Located in the Hillcrest area of San Diego just blocks to Balboa Park is Waterhaven, a non smoking, adults only retreat and the perfect place to enjoy your San Diego stay. 325 square feet, a fully private retreat that includes your own living space, bathroom, and kitchen. The guesthouse has dual paned windows, no shared walls, and the yard is fully protected with a stone wall for privacy and security. Waterhaven is a quiet, peaceful, relaxing experience.

Top Guest favourite
An Airstream is positioned on a hillside, surrounded by lush greenery and desert plants. Lounge chairs and a shaded patio area are visible, providing a space for relaxation. The backdrop features rolling hills under a clear sky, highlighting a peaceful and private setting.
Guesthouse in Spring Valley
4.98 out of 5 average rating, 402 reviews

Views•Sauna•SoakTub•Firepit+Zoo pkg add-on

Nestled in a hillside canyon, a short drive outside the city, this Airstream glamping retreat offers incredible panoramic city, sunset & nature views. Modern comforts include A/C & heat, a full kitchen, fast Wi-Fi, and convenient off-street parking on a gated estate. Cozy up by the firepit as the city sparkles below or try your swing at the golf tee. Reconnect & recharge with your own outdoor hot soaking tub, open-air rain shower, and wood-fired sauna - the perfect retreat for nature lovers!

Top Guest favourite
A green, manicured lawn is highlighted with a white gazebo and ornamental garden seating. Towering palm trees flank the scene, while a staircase leads up to a spacious home nestled in the background. Shadows create a gentle pattern on the grass from surrounding elements.
Guesthouse in Kit Carson
5 out of 5 average rating, 171 reviews

Infinity Poolside Apt. In San Diego Wine Country

170 Perfect 5.0 Reviews-Amazing views, peaceful and beautiful space in a wine country setting. A perfect setting to celebrate a special occasion and create memories. Amazing sweeping views of wine country, golf course and mountains on the 14th green of a golf course with full access to the estate pool, spa, covered parking, EV charger w/private European park. Large luxury suite with a Kitchen, Sitting Room, Bathroom, Steam shower/Sauna and bedroom with luxurious robes, linens and towels.

Top Guest favourite
The tropical pool features gentle waterfalls cascading into vibrant blue water. Surrounding palm trees and lush greenery enhance the serene environment. A tiki bar and a hot tub grotto provide inviting leisure options. A second-story balcony overlooks this tranquil outdoor space, illuminated by soft evening lights.
Guesthouse in La Jolla
4.97 out of 5 average rating, 193 reviews

Luxury Tropical Private Guesthouse in La Jolla

Beautiful private guesthouse on $5 million property with stunning views and luxury amenities. Take a dip in the tropical pool with waterslide, tiki bar, and hot tub grotto. Enjoy indoor or outdoor dining. Gated property, vaulted ceilings, marble bathroom, private balcony, parking, and trail for guests. Guesthouse has 1 bedroom with a queen bed and can accommodate an extra twin bed on the loft. House has closet, bathroom with beautiful stone shower, modern kitchen, two patios, WiFi, TV.

Top Guest favourite
The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.
Guesthouse in Lake Murray
4.96 out of 5 average rating, 136 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

This is your perfect Guest House with a salted & heated pool & hot tub. We are located in a super quiet & very safe neighborhood in beautiful San Diego, 15 minutes drive to beaches, Downtown, La Jolla, Zoo, Stadiums, Sea World, Convention Center + more. Hike next door at Mission Trails & Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo and top quality finishes and furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Top Guest favourite
The living area features natural wood paneling and a warm color palette. Large windows allow ample light, framed by woven shades. A comfortable white sofa and a stylish entertainment unit with a television are visible, along with a decorative chair and a small side table.
Guesthouse in Mission Beach
4.9 out of 5 average rating, 790 reviews

South Mission Beach Zen-Like Studio

This fully furnished second story South Mission bayside studio offers relaxed beach living. This studio sleeps 2 (Queen Bed) & 2 Boogie Boards are provided; private off street parking on premise. Bbq grill on small balcony. The unit is steps to the bay and short three minute stroll to the beach. Two beach cruiser bicycles provided which is one great way to get around the area. Please note, access to the second story is via an outdoor spiral staircase.

Top Guest favourite
A spacious bedroom features a large king size bed with a textured blanket, complemented by a nightstand and a decorative lamp. Sliding glass doors open to a deck, allowing natural light to fill the room. A flat-screen TV and a desk are visible in the background.
Guesthouse in Normal Heights
4.98 out of 5 average rating, 450 reviews

Mountain View Retreat in Gated Estate (Hot Tub)

Perched above a canyon with spectacular panoramic mountain views, this private guest house is a secluded retreat in one of San Diego’s most eclectic and desirable neighborhoods less than 6 miles from the Downtown San Diego airport. Enjoy a fully equipped kitchen, luxe king size bed and dual sliding glass doors that open to an expansive deck with patio seating, private hot tub and BBQ area.

Guest favourite
A spacious studio room features warm wooden walls and contemporary furnishings. A queen-sized bed is accompanied by accent pillows. Large double doors open to a private deck with garden views, while a work desk and chair are positioned near the entrance.
Guesthouse in Greater North Park
4.9 out of 5 average rating, 1,139 reviews

Safe Hip Quiet GARDEN STUDIO / Northpark

Come to a quiet and stylish studio to relax. Check-in contactless and enjoy! Cozy, hip and private garden studio with private entrance, private full bathroom, and private deck. The Studio house is in a large garden adjoining a craftsman-style house in the historic Northpark/ Morley Field District. Minutes away from coffee shops, breweries, Zoo, Balboa Park.

Popular amenities for San Diego guesthouses

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Quick stats about guesthouse rentals in San Diego

  • Total holiday rentals

    Explore 970 holiday rentals in San Diego

  • Nightly prices starting at

    San Diego holiday rentals start at $46 AUD per night before taxes and fees

  • Verified guest reviews

    Over 99,700 verified reviews to help you choose

  • Family-friendly holiday rentals

    120 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 240 rentals that welcome pets

  • Holiday rentals with a pool

    90 properties feature pools

  • Rentals with dedicated workspaces

    520 properties have a dedicated workspace

  • Wi-Fi availability

    960 of San Diego holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across San Diego rentals

  • 4.9 Average rating

    San Diego stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    San Diego's top spots, include Balboa Park, San Diego Zoo Safari Park, and La Jolla Cove

Destinations to explore