Guesthouse accommodation & holiday rentals in San Diego
Find and book unique guesthouse accommodation & rentals on Airbnb
Top-rated Guesthouses in San Diego
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouses
Family-Friendly guesthouses
Guesthouse in San Diego
4.97 out of 5 average rating, 506 reviewsCentral & Serene Secret Garden Guesthouse
17 – 24 Sept
Guesthouse in San Diego
4.92 out of 5 average rating, 366 reviewsCozy 1-bdr apt in Normal Heights near Adams Ave
11 – 18 Dec
Guesthouse in San Diego
4.91 out of 5 average rating, 379 reviewsNorth Park Cottage
7 – 14 Nov
Guesthouse in San Diego
4.97 out of 5 average rating, 291 reviewsPrivate Guest House with a View
6 – 13 Aug
Guesthouse in San Diego
4.96 out of 5 average rating, 211 reviewsNorth Park, San Diego's Best At Your Doorstep
3 – 10 June
Guesthouse in Kensington
4.96 out of 5 average rating, 251 reviewsYour Kensington Bungalow
14 – 21 Oct
Guesthouse in San Diego
4.81 out of 5 average rating, 430 reviewsStudio in the Heart of South Park!
7 – 14 Oct
Guesthouse in San Diego
4.94 out of 5 average rating, 332 reviewsThe BEST NEST Clean, peaceful, private, affordable
30 Oct – 6 Nov
Guesthouses with a patio
Guesthouse in San Diego
5.0 out of 5 average rating, 106 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
27 Dec – 3 Jan
Guesthouse in San Diego
4.98 out of 5 average rating, 122 reviewsPrivate Studio Cottage with Outdoor Patio
11 – 18 Dec
Guesthouse in San Diego
4.99 out of 5 average rating, 138 reviewsMission Hills-Entire Guest House-Center of it All
12 – 17 May
Guesthouse in San Diego
4.93 out of 5 average rating, 147 reviewsCentral studio w/ private outdoor space & parking
1 – 8 Oct
Guesthouse in La Mesa
4.98 out of 5 average rating, 249 reviewsLa Mesa Suite
11 – 18 Dec
Guesthouse in Oceanside
4.94 out of 5 average rating, 154 reviewsDetached, Private Cottage! Fenced, PET friendly!
22 Feb – 1 Mar
Guesthouse in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
23 – 30 Nov
Guesthouse in La Mesa
4.99 out of 5 average rating, 166 reviewsSDCannaBnB #1 *420 *parking *dog-friendly *hot tub
10 – 17 July
Guest house rentals with a washing machine and dryer
Guesthouse in San Diego
4.91 out of 5 average rating, 151 reviewsRelaxing Oasis - short walk to shops & recreation
6 – 13 Oct
Guesthouse in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
3 – 10 Sept
Guesthouse in San Diego
4.97 out of 5 average rating, 306 reviewsPrivate Guesthouse in Trendy North Park
15 – 22 May
Guesthouse in San Diego
4.92 out of 5 average rating, 526 reviewsThe Best Cottage in North Park!
26 Sept – 3 Oct
Guesthouse in San Diego
4.99 out of 5 average rating, 131 reviewsCarrie’s North Park Casita, in Heart of San Diego
13 – 20 Oct
Guesthouse in San Diego
4.91 out of 5 average rating, 114 reviewsCharming Granny Flat Near SDSU & Transit Center
4 – 11 June
Guesthouse in La Mesa
4.99 out of 5 average rating, 132 reviewsStunning Guest House 15 min. from Zoo, Downtown
20 – 27 Sept
Guesthouse in San Diego
4.98 out of 5 average rating, 117 reviewsCasita Hermosa - Close to everything in San Diego
25 Nov – 2 Dec
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
Destinations to explore
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