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Pet-friendly holiday rentals in Mesilla

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Mesilla

Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

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Guest favourite
A covered outdoor seating area is illuminated by string lights, creating a warm ambiance for evening relaxation. Comfortable seating is arranged around a central fire table, while a hammock is visible nearby. The space features a combination of brick and stone textures.
Townhouse in Las Cruces
4.96 out of 5 average rating, 299 reviews

The Ritz Spa Sanctuary hot tub/patio/fam/pet

Come unwind and rejuvenate at our zen sanctuary, where relaxation, simplicity, and comfort are key to a great stay! Pamper yourself in our spa like walk-in rain showers! Enjoy our newly remodeled contemporary interiors with natural terrecota concrete throughout. Private patio enjoy grilling with friends and family or spend a romantic evening sitting around the fire table or in the Hot tub! NMSU 5mi, White Sands 45mi, Less than 1 min access to Hwy-70, I-10,I-25 Old Mesilla 5mi, sec to Hospital

Top Guest favourite
The kitchen features blue cabinetry and colorful Talavera tile backsplash, enhancing its visual appeal. A window allows natural light to illuminate the space, while stainless steel appliances, including a microwave and dishwasher, are present. Wood countertops provide a warm contrast to the cabinetry.
Guesthouse in Las Cruces
4.96 out of 5 average rating, 143 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Guest favourite
An interior space showcases wooden accents and a warm ambiance. A dining table with vintage-style chairs is set for guests, featuring tableware arranged neatly. Various mirrors reflect natural light from skylights above, while unique windows with shutters add character to the room.
Campervan/RV in Las Cruces
4.96 out of 5 average rating, 108 reviews

The Stranded Time Traveler; a timeless experience!

Like something out of a fairy tale, the time machine's beauties are enchanting and memorable. Set somewhere in the past and present, it is being held in a large storage yard (plenty of space) because of flux capacitor issues while time marches on. Centrally located, it is about 3 mins. from NMSU, 5 mins. from Old Mesilla, the Billy the Kid court house, and the Farmers Market, 20 mins. from Dripping Springs Natural Area, 40 mins from El Paso, and 45 mins. from White Sands National Park.

Guest favourite
An inviting outdoor space features a heated pool and spa surrounded by palm trees. The unique pool shape complements the natural stone walls, while the sunset sky adds a warm glow. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Home in Las Cruces
4.96 out of 5 average rating, 149 reviews

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Freshly remodeled luxury home in the heart of Las Cruces, located just 5 minutes from down town in a safe quite neighborhood! Enjoy local restaurants and bars just minutes away! Wood floors throughout the home, with granite countertops and brand new appliances!Massive open floor plan in the kitchen area with an 85 inch TV and surround sound system! Heated Pool and Spa for year round use! Pet friendly fully enclosed back yard! You will never want to leave this Luxury Oasis!

Top Guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Guest favourite
A single-story home showcases a traditional adobe exterior with a tiled roof. A well-maintained front yard features low-maintenance landscaping, including gravel, shrubs, and rocks. The driveway leads to a two-car garage, and a covered porch adds an inviting touch to the entryway.
Home in Las Cruces
4.99 out of 5 average rating, 190 reviews

"Casa de Maíz" centrally located - close to NMSU

"Casa de Maíz" is a quaint home close to New Mexico State University, the Las Cruces Convention Center, and has access to downtown and Historic Mesilla. The home is in a quiet neighborhood close to a park where you can take your children or your dog(s). The home is a perfect stop on a cross-country trip or a place for temporary housing. The sunsets from the backyard are breathtaking. You will be inspired to go hiking while viewing the Organ Mountains from the front yard.

Guest favourite
Home in Las Cruces
4.9 out of 5 average rating, 130 reviews

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

Superhost
Double glass doors stand open, leading into the interior space from a small private courtyard. A welcoming doormat is positioned at the entrance, illuminated by soft lighting, while sheer curtains frame the doorway, allowing a glimpse into the cozy ambiance within.
Apartment in Las Cruces
4.86 out of 5 average rating, 248 reviews

Emily’s Le Garage, historic district, King Bed!

*****minimum 30 day rental**** This studio apt is is located in historic Alameda Depot downtown, within blocks of farmers market, restaurants, library, park, and more. Bathroom, kitchenette with Stove,coffee maker, coffee, essentials for cooking, microwave, large closet, king bed, sofa, TV, private courtyard and access to larger courtyard. Washer/dryer. It's great for short stays but also works well for long stays. MUST ACCESS CHECKIN FROM APP

Top Guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 356 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top Guest favourite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 204 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Superhost
A spacious living area features a large gray sectional sofa with decorative cushions. A wooden coffee table sits in front, while light fixtures illuminate the room. The kitchen area is visible in the background, showcasing white cabinets and a decorative tile backsplash.
Home in Las Cruces
4.88 out of 5 average rating, 276 reviews

4 Bedroom Contemporary Model home

This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

Top Guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 216 reviews

Cozy Casita De Mesilla

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Mesilla pet-friendly home rentals

When is the best time to visit Mesilla?

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Quick stats about holiday rentals that are pet-friendly in Mesilla

  • Total holiday rentals

    Explore 40 holiday rentals in Mesilla

  • Nightly prices starting at

    Mesilla holiday rentals start at $71 AUD per night before taxes and fees

  • Verified guest reviews

    Over 3,030 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    30 of Mesilla holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests – averaging 4.9 out of 5!