Skip to content

Vacation rentals in Mesilla

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesilla

Guests agree: these stays are highly rated for location, cleanliness, and more.

SUPERHOST
  1. Entire home
  2. Las Cruces
Mesilla 1869 Adobe 2 blocks from plaza

I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

SUPERHOST
  1. Entire guesthouse
  2. Las Cruces
Yucca Casita in Historic Mesilla

We have created a vision for this property of sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

SUPERHOST
  1. Entire place
  2. Las Cruces
Mesilla Plaza Historic Gem

Josefina's is located just off the historic square in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our southwestern beauty and the shared Garden Greenhouse the home offers a cozy step back in time. Our luxurious King Suite weaves together old world charm of an historic Southern New Mexico home and modern comforts like a feather top bed, mini fridge, cold AC, plush bathrobes and more.

Holiday rentals for every style

Get the amount of space that is right for you.

  • Homes
  • Hotels
  • Unique stays

Other great holiday rentals in Mesilla

SUPERHOST
  1. Entire guesthouse
  2. Las Cruces
Casa Elena Adobe casita in historic Mesilla
SUPERHOST
  1. Private room
  2. Las Cruces
Mesilla Traveler's Choice Easy on/off to I-10
SUPERHOST
  1. Entire guest suite
  2. Mesilla
Charming Casita in Historic Mesilla
SUPERHOST
  1. Entire guesthouse
  2. Las Cruces
Ocotillo Casita in Historic Mesilla
SUPERHOST
  1. Entire guest suite
  2. Las Cruces
Welcome to Casita Escondida in Mesilla, NM!
SUPERHOST
  1. Entire home
  2. Las Cruces
Charming Adobe One Block from the Mesilla Plaza
  1. Entire rental unit
  2. Las Cruces
Lovely 1-Bedroom Adobe Escape
SUPERHOST
  1. Entire townhouse
  2. Mesilla
Modern Townhome in Quiet Mesilla
SUPERHOST
  1. Entire home
  2. Mesilla
Casa Del Sol-Peaceful Retreat
SUPERHOST
  1. Entire rental unit
  2. Las Cruces
Casa Susana
SUPERHOST
  1. Entire rental unit
  2. Las Cruces
Bowman Casita Alameda Depot king bed
SUPERHOST
  1. Entire guesthouse
  2. Mesilla
Charming Adobe Casita near Plaza
  1. Airbnb
  2. United States
  3. New Mexico
  4. Doña Ana County
  5. Mesilla