
Guesthouse holiday rentals in Lake Hartwell
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Lake Hartwell
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Lake Hartwell guesthouses
Family-Friendly guesthouses

Holly Hideaway! 10 Highway miles to Clemson U!
Jen’s Hideaway is the perfect private spot to come back to after visiting Central and Clemson. It is extremely clean and well appointed. The bed is very comfortable. Jen is a friendly host. She even baked us delicious blueberry muffins.

La Bella Farm
Had an amazing time at this gorgeous space. It was exactly as advertised, and Jessica was extremely responsive and proactive as a host. Thank you so much! Will definitely book there again!

Mountain Edge Loft
Marsha Lynn's loft was cozy, private and pristine, with a beautiful view. The amenities were generous, as was the provided local guidebook. Marsha Lynn was responsive, thoughtful and professional. Couldn't be happier with our stay!

Historic 19th Century Cabin/Guest House
The cabin is a cute, spartan place. Tony was responsive to our messages & handled our issues. The bed's a bit on the older side; not necessarily the most comfortable. Close to downtown Greenville yet far enough for peace.

Betty's Creek Loft in Rabun Gap.
Absolutely loved staying at Matthew and Beverly’s place! The open scenery and view of the mountains was amazing to wake up to each morning. Exploring their land and the creek was just enough adventure for me! We will definitely be back.

Lisa’s Lodge
Lisa's Lodge was wonderful; just perfect for the two of us. It was so nice to take a dip in the lovely pool, sit by the the beautiful lake and take walks around the grounds and up the road. Proximity to Anderson yielded a couple of good restaurants and it was also an easy trip to Greenville and its charms. Lisa is very nice and her son offered help in case we needed it during a rainstorm. What a happy experience! We both want to go back!
Guesthouses with a patio

Guest Cottage with Private Drive
Dustin was easily accessible and quickly responsive when I had questions. his accommodations at the cottage far exceeded my expectations. I would definitely recommend for other guests to try it out. and if in the area again I would definitely try to stay there. highly recommended.

Secluded Lake-House Get-Away: Sleeps 4
kind responsive and the place was great. comfy beds and overall a great place

One Particular Cove ... on Lake Hartwell
We couldn’t be happier with our stay. Perfect size for the 4 of us. Ginny and Sid are wonderful hosts. Our flight was changed and delayed and we didn’t arrive till 3am and had to leave for Clemson graduation by 730am. With little to no time to sleep or eat breakfast they stocked the place with fresh pastries, fruit and bagels and cream cheese. We sadly were only to spend nights at the property so we did t get a chance to take the whole lake location in. I’d go back in a heartbeat

Charming Waterfront Guest House
Beth’s place is amazing. We have stayed here before and loved it so much we came back to stay again. It’s a beautiful house on the water with a pristine guest house that’s private, extremely clean, and very well maintained. Beth is incredibly friendly and always a great communicator. Would highly recommend, 10/10. Thanks Beth!

Serene country escape on 11 acres-20% off last min
Quiet, peaceful, stay. Amy was very responsive and helpful with local recommendations. We enjoyed our stay with our two dogs, felt right at home!

Fun, cozy cottage for two w/games, deck in Easley
We enjoyed our stay on a trip to Clemson for a graduation. It was easy to find and so peaceful and quiet. Shannon and David have done a wonderful job of decorating and we enjoyed looking at everything. They pay attention to detail which makes for a pleasant stay. The kitchen had everything and the bathroom was clean and every need was provided for. We would definitely stay here again.

Coltsfoot Cottage
Due to unforeseen circumstances at home, I had no other option other than to leave within 24 hours of having arrived to Jennifer's incredible cabin. Our paths did not even cross, though I would have liked to have met Jennifer and her husband. Did meet their friendly dogs, however. Jennifer even tried to have the two, unused nights' accommodation refunded back to me... and were 50% successful. Very kind of them; Unexpected, as my early departure had nothing to do with them. It was an urgent matter that required my return home immediately. So, I sincerely thank these great hosts for their understanding. Respectfully, Robert

Tranquil 2BR Guest House on Pond by Furman
Our stay at Gabriella's was wonderful. It is close enough to major roads to get anywhere quickly yet in a quiet neighborhood and very private. The living room was comfortable, the kitchen was well equipped, the bedrooms were large and everything was beautifully decorated. With family new to the area, I've already asked to stay there again!
Guest house rentals with a washing machine and dryer

Cozy Rustic Lakefront Cabin
The cabin was great! Neat decorations highlighting that this is an older cabin that has been fixed up but still shows off the history of being a lake house and antique furniture throughout. Nice having coffee on the porch listening to the birds. We walked out on the dock but didn’t stick around, but we said it would be a fun thing to do to go swim by the dock and spend the day there. There isn’t much to eat nearby and there isn’t a full “kitchen” in the cabin, but definitely sufficed for us! Sherri was very helpful and responsive with recommendations. We visited many wineries nearby before going to stay one night there. Thanks!

Quiet King Two Bedrm House
This was a quiet spot with friendly neighbors. Be careful if you walk to Travelers Rest as some dogs are off leash. One chased me onto a porch. This was a cross street to the rental location. The rest of the stay was nice and the hosts were very accommodating!

Clemson Carriage House - NEW!
Ashley‘s carriage house was such a cute place to stay. It is very central in Clemson to everything you would need to go to and was perfect to attend an event in Clemson. Is extremely clean and I especially loved all the Clemson Tiger touches in decor. I would stay here again if I came back for a Clemson game!

Adorable Cottage 2 mi. from Death Valley
Clean, peaceful, great location to the campus. Hosts are friendly and kind. My second stay and I can’t wait to go back.

Hartwell Hideway
We brought our teen daughter and our family dog to Clemson for a tour. This lake cabin was delightful. Angela helped us with supplies for our dog and a late checkout. The walk to the lake is just a few feet, and our dog enjoyed a quick swim. Just a few minutes from Clemson.

Vacation Home Clemson and Lakes
We had a wonderful stay in this beautiful home for our Tiger's graduation from Clemson. The home was extremely clean and well stocked with everything we needed. We enjoyed the backyard and patio as well. The host was friendly and responsive.

Pine Trees Rest
Beautiful guesthouse! It was very clean and was exactly as pictured. Alexandra greeted us upon our arrival even though it was a little late. She is quick to respond to messages. I definitely recommend her home and will stay again when we are in that area.

Nishleigh's Nook - West End Downtown Greenville
Such a great find, and walkable to W. Greenville, Unity Park, Swamp Rabbit Trail, West End, and the south end of downtown. The space was well-appointed, clean, and with your own back entrance opposite the main house, felt very private. Looking forward to staying at Nicholas and Ashleigh’s place again the next time we’re in GVL!
Destinations to explore
- Rentals with a patio Lake Hartwell
- Lakehouse rentals Lake Hartwell
- Beachfront rentals Lake Hartwell
- Rentals with breakfast Lake Hartwell
- Kid-friendly rentals Lake Hartwell
- Rentals with lake access Lake Hartwell
- Rentals with a washing machine and dryer Lake Hartwell
- Rentals with a fireplace Lake Hartwell
- Rentals with a fire pit Lake Hartwell
- Cottage rentals Lake Hartwell
- Condo rentals Lake Hartwell
- Pet-friendly rentals Lake Hartwell
- Private suite rentals Lake Hartwell
- Tiny house rentals Lake Hartwell
- Rentals with a kayak Lake Hartwell
- Villa rentals Lake Hartwell
- Rentals with an EV charger Lake Hartwell
- Fitness-friendly rentals Lake Hartwell
- House rentals Lake Hartwell
- Rentals with a hot tub Lake Hartwell
- Waterfront rentals Lake Hartwell
- Cabin rentals Lake Hartwell
- Apartment rentals Lake Hartwell
- Rentals with pools Lake Hartwell
- Family-friendly rentals Lake Hartwell
- Rentals with outdoor seating Lake Hartwell
- Guesthouse rentals United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom