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Holiday houses in La Mesilla

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Top-rated holiday rentals in La Mesilla

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A bright dining area features a wooden table with several chairs, accompanied by a cozy seating arrangement beside a large fireplace. Natural light flows through the windows, enhancing the warm tones of the wooden beams and adobe walls.
Chalet in Santa Fe
4.94 out of 5 average rating, 330 reviews

Five Level Artist Retreat on Tano Road - Sleeps 8+

This five-level 4 bdrm 2 ba artist retreat has been freshly renovated to merge post modern style, easy comfort and traditional charm. Enjoy spectacular sunrises, sunsets and star gazing on the 5th level of the house while enjoying the warmth of a large fireplace. Special design touches include river rock lined showers, unique tile accents and the warmth of wood textures and finishes throughout. Only 15 minutes to the historic Santa Fe Plaza, this home has a lovely courtyard and plenty of parking

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Top Guest favourite
A cozy sleeping area features a spacious bed adorned with fluffy white pillows and a light duvet, surrounded by large windows allowing natural light to illuminate the space. Two soft, circular poufs rest on a rug, contributing to the inviting atmosphere.
Cottage in Santa Fe
4.96 out of 5 average rating, 368 reviews

Sky-filled 'Studio Cielito' @ Rancho Los Sonadores

Welcome to Studio Cielito - a desert-inspired cottage designed with bath lovers in mind. Curated with vintage touches, luxury linens, and everything you need to relax and rejuvenate near the magical Sangre de Cristo Mountains. Just 8 mins from Meow Wolf and 14 mins from The Plaza, but surrounded by nature with a country feel. If your dates are not avail, click on our profile for our other rentals. **Due to COVID-19, we are asking that all guests be vaccinated to help keep our community safe.

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Top Guest favourite
A charming adobe casita is set against a lush green landscape, surrounded by trees and shrubs. A tranquil atmosphere is created by the expansive lawn and gently swaying plants. The casita features a sloped metal roof and large windows that invite natural light.
Guesthouse in Chimayo
4.94 out of 5 average rating, 198 reviews

Private Retreat with Stunning Views:West

Experience the splendor of the New Mexico countryside during your stay in our beautiful adobe casita. Located on a historic property, 35 minutes North of Santa Fe, in the village of Chimayo. The casita features hand plastered mud walls, soaring ceilings, luxury linens, large picture windows & private decks, in-room coffee maker, small fridge & microwave. Start your day with coffee next to the bubbling pond and end your adventures with a cocktail, taking in an epic sunset in the apple orchard.

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Guest favourite
A series of images showcases the guest house and farm setting. The large bedroom features a king bed and natural light from a window. The farmhouse kitchen includes wooden cabinets and cooking utensils. The organic garden reveals rows of vegetables, while a chicken interacts with a simple nesting area.
Farm stay in Santa Fe
4.92 out of 5 average rating, 119 reviews

Nambé Farm Stay

Join us on our organic veggie farm, 20 minutes north of Santa Fe and 25 minutes from Los Alamos, in beautiful Nambé. Our guest house is a stand alone casita with a fenced-in yard for your dogs, on our 5 acre working-farm property. The space has a large bedroom with king bed and writing desk, a living room with a comfy leather couch, tv with streaming capacity, a large bathroom with a tub, shower, washer/dryer, and a farmhouse kitchen to cook in. There is WiFi through-out. Pop-up cot available.

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Guest favourite
A yurt sits elevated on a wooden deck, surrounded by desert flora. Colorful wildflowers bloom in the foreground, leading the eye towards the rugged red rock formations in the background under a clear blue sky.
Yurt in Abiquiu
4.92 out of 5 average rating, 637 reviews

Yurt Overlooking the Chama River in Abiquiu

T R A N Q U I L O A tranquil and rustic experience secluded yet easily accessible on a hillside below the stunning Cerrito Blanco in Abiquiu. This large, 24-foot yurt makes the perfect weekend or week-long getaway for a couple or family looking for a unique experience. Sip your coffee (an organic medium roast is provided) on the deck, practice yoga, meditate, read/write, gaze up at the Milky Way, bird watch and take in the beauty of the Chama River Valley, right in the heart of Tewa country!

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Top Guest favourite
The spacious studio features traditional adobe architecture with exposed wooden beams. A colorful woven blanket adorns the seating area, complemented by wooden furniture. A vintage lamp and decorative pieces add character. A cozy sleeping area is visible, along with natural light filtering through the window.
Guest suite in Santa Fe
4.85 out of 5 average rating, 566 reviews

The Family Casita Santa Fe/ Pojoaque

The Family Casita is the guest wing to a family home with a private separate entrance. This is a large elegant adobe with thick walls that keep it cool in the summer and provide old world charm. A very spacious 900 square foot studio space, it has two original fireplaces, one in the eat-in kitchen, and one in the main room. There is a beautiful hand painted king sized bed and a Euro Lounger (that converts to a double bed), separated by a privacy wall. Dogs welcome. Sorry can't accept cats.

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Top Guest favourite
Cottage in Santa Fe
5 out of 5 average rating, 526 reviews

Magical Desert Casita with Stargazing & Hiking!

I LOVE sharing my truly magical property with guests, and I have put so much love into this charming casita! It is located on the Turquoise Trail, a breathtaking National Scenic Byway. Poised on 10 beautiful acres with mountain views, you will be 17 miles from Santa Fe, 2 miles from the charming little village of Los Cerrillos, and 5 miles from the popular artsy mining town of Madrid. You can hike right out the door, and enjoy out-of-this-world star gazing, and amazing sunrises and sunsets!

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Superhost
Guesthouse in Española
4.65 out of 5 average rating, 23 reviews

Desert Hacienda Estate | La Casita

Stay in the Heart of the Land of Enchantment! Welcome to La Casita, your cozy private retreat in Las Mesilla, NM. Nestled in a peaceful two-unit compound, this charming space offers the perfect home base to explore Northern New Mexico. Just minutes from Santa Fe, Los Alamos, Taos, and beyond, you’ll be surrounded by breathtaking scenery, rich culture, and endless adventure. Whether you’re here for hiking, art, history, or relaxation, La Casita puts you right in the heart of it all.

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Top Guest favourite
A hot tub is situated on a wooden deck, surrounded by tall trees and a clear blue sky. The water's surface reflects the sunlight, creating a serene setting for relaxation amidst a forest backdrop.
Cabin in Jemez Springs
4.93 out of 5 average rating, 215 reviews

Cozy Forest Escape with Private Hot Tub

Escape to a Peaceful Forest Retreat Nestled on a 1.5-acre wooded lot, this relaxing cabin offers the perfect retreat for nature lovers and adventure seekers. Located adjacent to the Valles Caldera National Preserve, our property boasts: - Relaxing Hot Tub: Unwind among the pines - Wildlife watching opportunities - Short drive to Fenton Lake for top-notch fishing - Modern comforts for a peaceful stay - Proximity to outdoor activities for all seasons: hiking, biking, fishing, and skiing

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Guest favourite
The interior of the camper features a modern design with a spacious island in the center. Soft lighting is provided by decorative hanging lamps. A cozy seating area with a leather couch and two chairs is visible, complemented by natural light from large windows.
Campervan/RV in Española
4.94 out of 5 average rating, 206 reviews

Charming Camper near Santa Fe

Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

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Top Guest favourite
The entrance of a rustic casita is framed by a tree, featuring a shaded porch with a small table and two chairs. A potted plant adds a touch of greenery. The door is flanked by wall sconces, and a welcoming bell hangs above.
Guesthouse in Santa Fe
4.97 out of 5 average rating, 677 reviews

Beautiful View

Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.

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Superhost
Home in Española
4.5 out of 5 average rating, 4 reviews

Modern Dome Home between Santa Fe & Taos

Escape to this newly renovated 3BR/2BA mountain retreat! Set on a private 1/3 acre near the Rio Grande, enjoy a fenced yard, vast outdoor space, and a cozy wood-fired stove. High-speed WiFi included. Prime location: next to Starbucks/Walmart, 30 mins to Santa Fe, and <1 hour to Taos skiing. Whether you're hiking, skiing, or relaxing, this stylish home offers the perfect blend of modern comfort and Northern NM charm. Book your high-desert stay today!

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Popular amenities for La Mesilla holiday rentals