Boutique hotel holiday rentals in St. Louis County

4.85 out of 5 average rating, 765 reviews

The Maple Room Queen Bed at BnB in CWE!

CodyRating, 5 stars2 weeks ago

I’ve stayed here twice now. Both stays went perfectly well. Even though this is a shard bathroom/kitchen, you will hardly even notice. The real + is the amount of amenities that the bathroom has and that the kitchen has comparable to a hotel room is unbelievable! You have to see the shower it’s huge! He also responds immediately to any questions or requests that I’ve had. Every time I stay in St. Louis, I will always go back to Brandon’s.

4.9 out of 5 average rating, 123 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

4.73 out of 5 average rating, 66 reviews

The West End by Cortex, Forest Park, BJC & Zoo

Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

Superhost

4.84 out of 5 average rating, 105 reviews

Chic Ultramodern Minimalist Studio Loft + Patio

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, bwalk-in closet, and a lovely patio overlooking the courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

4.93 out of 5 average rating, 114 reviews

Chic Ultramodern Minimalist Studio Loft + Patio

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, track lighting, and a lovely patio overlooking the courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

5 out of 5 average rating, 26 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

Experience timeless elegance in The Hill Suite, where Gothic architectural details blend with modern luxury. Framed by original stained glass windows, this retreat features rich wood finishes and soaring ceilings. Unwind in your plush queen bed or cozy up by the ambient electric fireplace. The spa-like en-suite bathroom offers heated floors, designer tilework, and a deep soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Hotel room in Alton

4.95 out of 5 average rating, 39 reviews

Three Bedroom River View Guest House-3 Bathrooms

An escape from the ordinary in our River view guest house. On bottom level is an art glass shop offering classes in stained , fused, and mosaic art glass you may partake in at an additional cost. Bicycle built for two available for cycling the national scenic byway. Walk to shops, casino, restaurants, breweries, and concerts. Cruise ship dock is 1/2 mile away. Extend your stay before or after to enjoy taking a stained glass class offered in our shop below as a souvenir of your trip.

Superhost

Hotel room in Brentwood

The Best of Suite Living! Ideal for Work & Leisure

By staying at our property, you can make the most of your trip, whether it's for work or pleasure. We are conveniently located near renowned destinations including Hanley Park, the St. Louis Children's Aquarium, and Oak Tree Park in the Brentwood neighborhood. We are close to Whole Foods Market, Applegate's Deli, and Camille's Sidewalk Cafe, among other well-known restaurants. You can grab a free breakfast in the morning and get a head start on your day. Enjoy the free parking and Wi-Fi.

4.91 out of 5 average rating, 120 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

4.91 out of 5 average rating, 134 reviews

Gorgeous Ultramodern 2BR Corner Loft + Workspace

The Nash Loft is a stunning corner loft with two spacious bedrooms, two designer bathrooms with black stainless fixtures and frameless glass showers, 12’ ceilings, a comfortable workspace with high-speed internet connection, stackable washer + dryer, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

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Popular amenities for St. Louis County Boutique Hotels

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Family-Friendly Boutique Hotels

4.85 out of 5 average rating, 765 reviews

The Maple Room Queen Bed at BnB in CWE!

CodyRating, 5 stars2 weeks ago

I’ve stayed here twice now. Both stays went perfectly well. Even though this is a shard bathroom/kitchen, you will hardly even notice. The real + is the amount of amenities that the bathroom has and that the kitchen has comparable to a hotel room is unbelievable! You have to see the shower it’s huge! He also responds immediately to any questions or requests that I’ve had. Every time I stay in St. Louis, I will always go back to Brandon’s.

4.9 out of 5 average rating, 899 reviews

King Redwood Bedroom at BnB in CWE!

TremainRating, 5 stars2 weeks ago

Everything Was wonderful and clean as it look on the picture. Cozy big bed , 2 big tvs , quite neighborhood. Definitely worth it

4.87 out of 5 average rating, 720 reviews

Blue Spruce Room Queen Bed at BnB in CWE!

TannerRating, 5 stars3 weeks ago

Great stay, second time in this location, will be interested in coming back

4.87 out of 5 average rating, 634 reviews

Evergreen Room Queen Bed at BnB in CWE

JocelynRating, 5 stars3 weeks ago

We really enjoyed this Airbnb! They had such clear instructions both in the bathroom and kitchen - I wish more Airbnb’s were that thorough.

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Boutique Hotels with a patio

4.97 out of 5 average rating, 34 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

HeatherRating, 5 stars1 month ago

The building is gorgeous, wonderful design, welcoming and comfortable rooms. We had everything we needed for our romantic overnight. The view from the hot tub at night can't be beat, and the two person soaker tub in the Riverfront room really was big enough for two!

Hotel room in Saint Charles

4.69 out of 5 average rating, 232 reviews

1st Capitol Mansion Boutique Hotel - Suite 301

AaronRating, 5 stars4 days ago

We stayed in a small unit - It is just a bedroom and a bathroom - but it was all we needed. I liked it because we couldn't have made use of anything else so the price was excellent AND we there is comfy little coffee shop across the street and I was able to walk into the historic area and around by the river. If I was looking for something super fancy - this wouldn't be it. It was clean, matched expectations, instructions were clear. We would stay again!

5 out of 5 average rating, 12 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

AkshayRating, 5 stars4 months ago

This is a hidden gem that is maintained exceptionally well. The check in was smooth and the owners are very friendly. Only time we saw them was when we checked in and they gave us a tour of the place. The entire property is squeaky clean and provides every comfort offered in a five star hotel. I've stayed in many five star hotels across the world (Ritz Carlton, Four Seasons, Waldorf Astoria) and this is arguably better than those places given the unique experience it offers and the character of this place. I would definitely recommend this to anyone looking for a unique experience in St. Louis. It is also located in close proximity to a lot of local attractions.

Hotel room in Saint Charles

5 out of 5 average rating, 14 reviews

#3 Betty Bloomer Le Velo Inn

EricRating, 5 stars2 days ago

We really enjoyed our stay at Le Velo in one of their well-appointed suites. The finishes and furnishings were the nicest of any Airbnb we had stayed in before and it was obvious that much care went into creating a really special space for guests (heated seat toilet/bidet was my personal favorite). We love the historical aspect of the entire place (being an original boarding house from the 1800s) as well as the historical theme of the particular room and how much effort was made to reflect that (Parisian chandelier, reuse of vintage doors, etc.) Logistically, it was very easy to get in and out. It was a great location in the Frenchtown part of Old St. Charles, which is a quieter, less developed historical area, but a short 10 minute walk from busier Main St. Area was quiet and safe and still had very close walking options for coffee/breakfast/pizza. And the outdoor lounge area was really nice even though we didn’t make use on this stay. Would love to come back again!

Superhost

Hotel room in Saint Charles

5 out of 5 average rating, 3 reviews

#6 The Green Tyke Le Velo Inn

SierraRating, 5 stars1 week ago

The best Airbnb i’ve ever stayed at. The aesthetics are amazing. I took pictures for inspiration -from the glasses to drink out of to the wall decorations - to the couch. I felt right at home & I have such a peaceful experience when I stayed here. I can’t wait to come back.