
Boutique hotels in Missouri
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Missouri
Guests agree: These boutique hotels are highly rated for location, cleanliness and more.

River Sirens Hotel Deluxe Suite
11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Every room as a very large balcony with river views. Each room is also equipped with a full kitchen featuring large refrigerators w/ ice dispensers, induction stove top, microwave, toaster, and coffee station.
LocationValueHospitality

Crown's Flower Suite, Live Music, Right Downtown!
Hermann 1837 Cellar Bar/Restaurant Onsite. Live Music Nightly May-Oct! It’s a Floral Delight in Our Flower Suite. A 2nd Floor Suite Filled with Flowers! Complete with Prints, Framings, and Collectibles Celebrating Flowers. King Bed, Electric Fireplace, Microwave, Mini Fridge, WiFi, & Cable. $20 Personalized All Day Shuttle Service (Trolley is $30). Free Pick Up/Return to Train Station & Free Electric Charging Stations. $50 per pet nightly fee. Free Drink Tickets & Free Buffet Breakfast.
ValueLocationQuiet

Historic Commercial Hotel(1868),Sally Rand Suite
The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.
FamilyValueAir conditioning

Queen room for two near wedding venues
Pilot 1 Room • Located on the second floor, this room is a more affordable option compared to our other rooms. • Features a queen bed and a half bath en suite. • Guests share 2 shower rooms located just outside the room with the 3 other Pilot rooms. • Includes a TV and desk in the room. Additional Amenities • Large community space on the first floor with a kitchen and activities. • Seasonal pool access. Other Rooms • Two Captain rooms on the first floor each have a full private bathroom.
ValueFamilySolo travel

“The Classic” at Rockwood Motor Court on Route 66.
Rockwood Motor Court, built in 1929, is located on historic Route 66. Each room is themed and furnished to the era of Route 66. “The Classic” showcases the automobiles on road in the 1940’s and 50’s. This room features vintage furniture, a full size bed, bathroom with dressing area, and corner shower. Renovated in 2019, enjoy a clean, comfortable room and experience authentic motor court lodging. Need more space? We also have larger rooms and can package multiple rooms for your group.
FamilyValueDecor

The Maple Room Queen Bed at BnB in CWE!
A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!
FamilyValueBreakfast

The Woodsman Suite
A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.
ValueLocationOutdoor spaces

Beautiful Historic Suite
The Hope Loft Suite, located on the second floor of Casa Di Vite International Wine Café," in Excelsior Springs, Missouri, offers a delightful place to stay. This exquisitely furnished loft is crafted to reflect the style of the early 1900s, featuring a generous king-size bed and an additional room with a twin-size bed. A private staircase in the back offers access. Perfect for weekend getaways, wine-tasting trips, or a peaceful solo retreat.
LocationFamilyCleanliness

Lavender Paradise: Room #26 at The Bradford
Come enjoy a relaxing stay at The Bradford! Easy access to the Branson Strip and only 5 minutes from Silver Dollar City! Our rooms are newly remodeled, and each have their own uniqueness. The complimentary coffee bar and game room are everything you need before a fun-filled day in Branson! There’s no other view of the Branson strip quite like The Bradford’s! You won’t want to leave this charming, one-of-a-kind property.
LocationValueAir conditioning

Wentworth Mansion Suite 1
Our suites are housed in the historic first barracks of the Wentworth Military Academy, located at the corner of 16th and Main in Lexington, Missouri. Each room is designed with elegant 1800s décor, offering a unique step back in time. Suites include a full-size bed, a spacious seating area, a private bath, and modern amenities such as YouTube TV, Amazon Prime, a mini refrigerator, a coffee maker, and more.
LocationValueCondition

Culture Boutique Hotel: Casablanca Suite.
Our loft-like suites feature furniture made from reclaimed materials from our building, a converted mattress factory. Each suite is inspired by a city in Eurasia. The rooms boast high ceilings, a 39in tv, a refrigerator, microwave and a V60, Electric Kettle, + complimentary coffee from Eurasia Coffee Co. This room (Casablanca) boasts a jacuzzi and separate shower.
ValueFamilyWalkability

430 West Front: Balcony Riverfront View
This room is located on the second floor over our quaint wine bar with a private balcony overlooking the Missouri River. Enjoy a cup of coffee or glass of wine from our wine bar on your private balcony. Just steps from our Historic downtown riverfront community with plenty of bars, restaurants, and charming shops to explore.
ValueFamilyAccess
Popular amenities for Missouri boutique hotels
Family-friendly boutique hotels

#8 A 1930’s Motor Court, Historic Randles Court
FamilyLocationNearby

Labby's Homestead Rolling Creek Loft Suite
FamilyLocationNearby

The Executive King Suite
FamilyLocationKitchen

The Atrium - A Boutique Hotel - Suite 18
FamilyLocationSleep quality

American Family Owned/Operated Motel
LocationFamilyOutdoor spaces

Room 101 · The Inn at Elijah McLean's - Room 101 (
ValueLocationIndoor spaces

Westgate Branson Woods | Queen | Outdoor Escape
LocationFamilyQuiet

Depot Inn & Suites - King Room
FamilyLocationHospitality
Boutique hotels with a patio

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
LocationValueBreakfast

Weingarten Vineyard Luxurious Suite #2
LocationAmenitiesAir conditioning

Clara & Russell Stover at Southmoreland
LocationComfortIndoor spaces

TheInn on Main Fairfax-private room/bath, no steps
FamilyLocationAccuracy

The West End by Cortex, Forest Park, BJC & Zoo
LocationValueParking

Penthouse Suite
Comfort

Secluded Rustic theme Hotel - Queen room
FamilyLocationQuiet

1st Capitol Mansion Boutique Hotel - Suite 201
LocationFamilyCheck-in
Other boutique hotel holiday rentals

Riverfront Boutique Inn in Downtown Hermann!
ValueLocationCheck-in

Vinchester Inn | King Bed, Boutique Hotel
ValueLocationTV

Vinchester Inn | Queen Bed, Boutique Hotel
FamilyLocationCheck-in

“Camp Rockwood”at Rockwood Motor Court on Route 66
FamilyValueIndoor spaces

Blue Spruce Room Queen Bed at BnB in CWE!
FamilyValueQuiet

King Redwood Bedroom at BnB in CWE!
LocationFamilyHospitality

Crown's Katy Trail Suite, Food/Bar/Music Onsite
LocationValueSleep quality

Crown's 2 Bed Vineyard Suite, Live Music, Downtown
FamilyLocationBreakfast
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