Guesthouse holiday rentals in Missouri
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Missouri
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Missouri guesthouses
Family-Friendly guesthouses
Guesthouse in Salem
4.81 out of 5 average rating, 313 reviewsCourtesy Curve Traveler's Rest
3 – 10 Oct
Guesthouse in Birch Tree
4.78 out of 5 average rating, 174 reviewsCollier Cabin in Pine Hollow ~ Eminence, MO
24 – 31 Dec
Guesthouse in Marthasville
4.96 out of 5 average rating, 222 reviewsHazel's House by the Katy Trail
18 – 25 Nov
Guesthouse in Columbia
4.95 out of 5 average rating, 205 reviewsNature guesthouse by the A frame Studio
18 – 25 Nov
Guesthouse in Kansas City
4.98 out of 5 average rating, 112 reviewsNorthfield Village Private Apartment
18 – 25 June
Guesthouse in Hermann
4.99 out of 5 average rating, 115 reviewsGrapevine Guesthouse
26 Sept – 3 Oct
Guesthouse in St. Louis
4.89 out of 5 average rating, 854 reviewsUnique Carriage House: Fun for the whole family!
12 – 19 May
Guesthouse in Sunrise Beach
4.99 out of 5 average rating, 68 reviewsHoneymoon Retreat with Hot Tub & Great View
24 Nov – 1 Dec
Guesthouses with a patio
Guesthouse in Branson
4.81 out of 5 average rating, 113 reviewsLavender Paradise: Room #26 at The Bradford
25 Sept – 2 Oct
Guesthouse in Independence
4.88 out of 5 average rating, 69 reviewsAdorable one bedroom Guesthouse in the woods.
31 Jan – 7 Feb
Guesthouse in Weston
5.0 out of 5 average rating, 49 reviewsLittle cottage in the woods
6 – 13 Aug
Guesthouse in Joplin
4.99 out of 5 average rating, 99 reviewsMike & Angie’s Private-Cozy furnished Guest House
16 – 23 Oct
Guesthouse in Rocheport
5.0 out of 5 average rating, 54 reviewsJust off the beaten path
6 – 11 July
Guesthouse in Blue Eye
5.0 out of 5 average rating, 67 reviewsTurtle Cove- Hot tub, Paddle brds, Kayaks Included
27 Mar – 3 Apr
Guesthouse in Sarcoxie
5.0 out of 5 average rating, 45 reviewsQuiet Acres Hidenaway Off I-44
18 – 25 June
Guesthouse in Farmington
5.0 out of 5 average rating, 30 reviewsThe Dove's Nest established July 2023
25 July – 1 Aug
Guest house rentals with a washing machine and dryer
Guesthouse in Union
4.97 out of 5 average rating, 124 reviewsDog Friendly One Bedroom Guest House
15 – 22 Feb
Guesthouse in Webb City
4.96 out of 5 average rating, 403 reviewsBright and Modern Private Guesthouse near Route 66
20 – 27 Sept
Guesthouse in Fordland
4.77 out of 5 average rating, 119 reviewsMagnolia TINY HOUSE at Promised Land Farm
16 – 23 Sept
Guesthouse in St. James
4.92 out of 5 average rating, 156 reviewsSAVE, MO Cottage
27 July – 3 Aug
Guesthouse in Kansas City
4.96 out of 5 average rating, 137 reviewsPine Hill Farm
11 – 18 Dec
Guesthouse in Ash Grove
4.94 out of 5 average rating, 110 reviewsGRAND REOPENING Ash Grove home with a Zen feel
12 – 19 Aug
Guesthouse in St. Louis
4.81 out of 5 average rating, 208 reviewsCarriage Loft
5 – 12 May
Guesthouse in Poplar Bluff
5.0 out of 5 average rating, 12 reviewsCozy Apartment Glamping w/ pond and forest access!
26 Mar – 2 Apr
Destinations to explore
- Guesthouse rentals United States
- House rentals United States
- House rentals St. Louis
- Rentals with a hot tub Missouri
- Rentals with an EV charger Missouri
- Rentals with a washing machine and dryer Missouri
- Condo rentals Missouri
- Fitness-friendly rentals Missouri
- Tree house rentals Missouri
- Rentals with breakfast Missouri
- Ski-in/ski-out rentals Missouri
- Rentals with a sauna Missouri
- Wheelchair accessible rentals Missouri
- Tiny house rentals Missouri
- Farmstay rentals Missouri
- Bed and breakfasts Missouri
- Kid-friendly rentals Missouri
- Lakehouse rentals Missouri
- Hotel rentals Missouri
- Campsite rentals Missouri
- Private suite rentals Missouri
- Rentals with outdoor seating Missouri
- Rentals with a fire pit Missouri
- Cabin rentals Missouri
- Rentals with lake access Missouri
- Beachfront rentals Missouri
- Rentals with a patio Missouri
- Rentals with an accessible height bed Missouri
- Waterfront rentals Missouri
- Rentals with beach access Missouri
- Townhouse rentals Missouri
- Boutique hotel rentals Missouri
- Rentals with pools Missouri
- Monthly Rentals Missouri
- Rentals with a kayak Missouri
- Loft rentals Missouri
- Smoking-friendly rentals Missouri
- Apartment rentals Missouri
- Villa rentals Missouri
- House rentals Missouri
- Rentals with a fireplace Missouri
- Chalet rentals Missouri
- Rentals with a home theatre Missouri
- Family-friendly rentals Missouri
- Rentals with an accessible height toilet Missouri
- Cottage rentals Missouri
- Pet-friendly rentals Missouri
- Serviced apartment rentals Missouri
- House rentals Lake of the Ozarks
- House rentals Lake Ozark
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom