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Holiday houses in Santo Domingo

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Top-rated holiday rentals in Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Cottage in Playa El Jobo
4.77 out of 5 average rating, 125 reviews

Enjoy a beach house facing the ocean, patio

Playa El Jobo is a magical place, special for connecting with nature and resting. It is oceanfront at a height of 9 meters, which allows you to receive the cool sea breeze. The property has a wooden house with a first floor and an upper floor. On the ground floor you will find the kitchen, two full bathrooms, two outdoor showers and a covered space with hammocks. Upstairs there is a large balcony with hammocks, two bedrooms, a living area and two bathrooms. There is good lighting, natural ventilation and A/C

Guest favourite
Villa in Playa Venao
5 out of 5 average rating, 11 reviews

Playa Laska – Oceanfront Escape with Infinity Pool

Welcome to Playa Laska, a luxury beachfront villa where tropical elegance meets modern comfort. With three beautifully designed bedrooms, a private infinity pool, and open-air decks surrounded by lush greenery, every corner invites you to unwind, connect, and savor the ocean breeze. Start your mornings with the sound of waves, relax by the pool or stroll along the shore, and let evenings unfold with dining under the stars. Every corner is thoughtfully crafted for a seamless and relaxing stay.

Superhost
A welcoming entrance is framed by vibrant tropical plants, with a pathway leading to a covered porch. The structure features a tiled roof and red steps, providing an inviting transition from the outdoors to the interior space.
Home in Pedasi
4.85 out of 5 average rating, 20 reviews

Peaceful Pedasi

Peaceful Pedasi. Get completely away from the city and forget the rest of the world exists. Pedasí is a town and corregimiento situated on the south-eastern tip of the Azuero Peninsula on Panama’s Pacific coast. And although remote enough to feel protected from the stresses of life, Pedasi offers wonderful dining and shopping. Our home offers a full functioning kitchen, large dining space, 5 Bedrooms, 4 Bathrooms, 2 car garage, private pool, and cabana with your own view of the ocean.

Superhost
Cottage in Pedasí
4.82 out of 5 average rating, 39 reviews

Drones Pedasi Ranch - Beach Pool Folk Fest Fishing

FAMILIES will Relax at this peaceful on the beach complete Ranch-House. Restaurant near by or drive (5) min to Pedasi's Town Center or Children can be kept close, a bunk-bed is near the King Size bed, with TV and Disney channel in the spacious Main room . Two other bedrooms with two Double-Bed each. All rooms with Bathroom and closet. Separate Kitchen & Dinning room with a relaxing view of the Ocean and wilderness. Ask us about tours to Isla Iguana, fishing trip or Horse back-riding.

Guest favourite
The exterior of a two-story building is shown, adorned with vibrant green vines and purple flowers. Sunlight illuminates the facade, enhancing the earthy yellow color of the walls. Large windows are visible, providing a connection to the outdoors.
Apartment in Pedasí
4.94 out of 5 average rating, 18 reviews

Pedasi Loft / Close To Town Activities / Pool / AC

My name is Malika, I'm a musician & yoga meditation teacher living in New York. Pedasi is my second home and my apartment is in the center of town, walking distance to all town activities restaurants and supermarket. The main beach (Playa Del Toro) is 2 km away & Playa Venao 28km south. The place is completely new designed by New York based developer. After years of using the space for myself I am opened to share this experience with you. Looking forward to host you in your next trip.

Superhost
Apartment in Las Tablas
4.6 out of 5 average rating, 81 reviews

2nd floor Beach Apartment with Amazing Views!

Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.

Guest favourite
Apartment in Las Tablas
4.94 out of 5 average rating, 16 reviews

Loft Conivan-Las Tablas

Enjoy Las Tablas as if you were at home in this spacious and comfortable full apartment. Located on the first floor. Equipped for short or long stays, with a full kitchen, cozy living room, air conditioning and WiFi, ideal for all types of travelers. Beaches, restaurants, supermarkets, and the town's main tourist attractions are just a few minutes away. Whether you're coming for a celebration, rest, or a walk, this home is the perfect starting point to enjoy Las Tablas.

Guest favourite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny home in Playa El Jobo
4.93 out of 5 average rating, 46 reviews

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Guest favourite
A modern tropical home is set amid lush greenery, featuring an expansive deck that connects to a serene pool. Large glass doors provide a view of the inviting interior and allow natural light to fill the space. Mountains and trees frame the backdrop.
Home in Playa Venao
4.97 out of 5 average rating, 78 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Superhost
Home in Playa Venao
4.89 out of 5 average rating, 75 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Superhost
Apartment in La Pasera
4.75 out of 5 average rating, 4 reviews

Comfortable apartment in Las Tablas, quiet area

Apartamento nuevo, muy cómodo y con mobiliario de lujo, diseñado para una estancia acogedora y elegante. Ubicado en una zona tranquila de Las Tablas, a 7 minutos del parque y a 15 minutos de las playas. Dispone de camas muy cómodas con colchones de alta gama y sábanas de alta calidad hotelera para un descanso reparador. Cuenta con zona de coworking y TV con streaming. Cocina completamente equipada. Ideal para disfrutar con total tranquilidad.

Guest favourite
A refreshing swimming pool sits in the foreground, complementing the rustic building behind it. Lush greenery and potted plants surround the area, enhancing the natural setting. A shaded patio area with outdoor seating is visible, offering a serene environment for relaxation.
Guesthouse in La Enea
4.96 out of 5 average rating, 55 reviews

Country House with Pool in La Enea de Guararé

Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Relax in the pool or rest in a hammock, breathe fresh air, near the sea, surrounded by spacious and natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

Popular amenities for Santo Domingo holiday rentals