
Holiday houses in Santiago
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Top-rated holiday rentals in Santiago
Guests agree: these stays are highly rated for location, cleanliness and more.
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Popular amenities for Santiago holiday rentals
Other great holiday rentals in Santiago

Private room in Calobre
4.64 out of 5 average rating, 11 reviewsHostal Brisas Calobreñas, A home to stay in Panama
BernadetteRating, 5 stars4 months ago
the bedroom in the back allows you to be quiet in privacy, installed on the small terrace in front. the bathroom is attached to the bedroom and used only by its occupants. Everything is very simple but clean. Kitchen equipment is basic but enough for us to cook. We are far from luxury, but in relation to the price, and the place is nice. the owners who live on site are welcoming and have always responded to our requests by trying to satisfy them. The wifi goes well. The weak point for us is the lack of storage.

Private room in Santiago
4.33 out of 5 average rating, 12 reviewscozy home, room and kitchen, rest on your trip.
NicoleRating, 5 stars22 months ago
I loved my stay with Federico’s family. They were all super welcoming and friendly. They cooked for me and we enjoyed the food while having great conversations. They also showed me around a bit despite the rainy weather. My room was clean and spacious, and the bed big and comfortable. They also gave me a towel, which is always highly appreciated. I would definitely come back next time I’m passing by Santiago. Special thanks to Diana and that amazing walk under the rain we had together!
Guest favourite

Private room in Santiago
4.83 out of 5 average rating, 6 reviewsComfortable rooms in Santiago
StirlingRating, 5 stars3 weeks ago
Yohana is so nice and the house is very clean and beautiful. There’s a huge grocery store only a 5-10 minute walk away. Great place!

Home in San Francisco
3.67 out of 5 average rating, 3 reviewsThe House of the Little Hill
MikeRating, 5 stars11 months ago
The casita has the essentials for a good stay, whether as a couple, friends, family, etc. The well-equipped kitchen, clean rooms/bathrooms. wifi accessible and what I liked the little house patio... HUGE.. You'll have to plan another little pass for San Francisco👍🏽. Mr. Alejandro's attention, 5 stars. Very friendly and attentive all the time.

Private room in Santiago
4.87 out of 5 average rating, 15 reviewsMain room-San Miguel Clean House, Santiago.
AllisonRating, 5 stars12 months ago
I made a mistake in my booking and Linssi was so kind and understanding on helping me fix it :) i would highly recommend staying with her as she is lovely and i know i will return .
Superhost

Private room in Santiago
New Santiago House
ninoskaRating, 5 stars6 months ago
very good people and very treatable only that the street is a little ugly what else is perfect
Guest favourite

Hotel room in Santiago
5 out of 5 average rating, 9 reviewsStandard Room - Hotel El Huésped
BrackenRating, 5 stars1 month ago
a nice friendly place to stay in Santiago. I stayed here between busses to Boquete and I walked from the station to the hotel and back in the morning. I found some amazing food nearby and slept well in the quiet cool room with great air-conditioning. I used the provided desk area for some writing, a pleasant surprise. if you need a stop in Santiago you can't go wrong here.

Private room in Nata
4.24 out of 5 average rating, 17 reviewsPrivate Room in Nata, Cocle, Panama
JonathanRating, 5 stars5 months ago
If you’re looking for a unique hostel experience, this is the place! It’s more like staying in a large, very unique home and building, with multiple rooms and shared spaces. I stayed on the top floor, which I thought the most interesting with its wooden, attic-like yet charming feel, as it opened onto a big deck with wonderful views and a hammock. The folks living there who receive you are wonderful, very friendly and welcoming. Lots of animals about which is fun, and beautiful trees. The breakfast which is included is also great and very complete. We had a little trouble getting into the place after hours since it’s a farm and there’s a shared main gate which is closed to keep cows in etc, at the lower part of the property - so maybe arrive earlier (before 6 pm) unless you make plans with Hermann to arrive later. Also, Hermann can take a few hours to respond, so book a bit in advance to handle all necessary communications. Was a great one night stay over for me and happy to recommend.
Quick stats about holiday rentals in Santiago
Total rentals
60 properties
Nightly prices starting at
$15 AUD before taxes and fees
Total number of reviews
460 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
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