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Holiday houses in Santa María

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Top-rated holiday rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guesthouse in El Valle de Antón
4.99 out of 5 average rating, 114 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Superhost
A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.
Home in Chitre
4.86 out of 5 average rating, 65 reviews

Country House Like in the City / La Casita

Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Guest favourite
Home in Lagartero
4.86 out of 5 average rating, 22 reviews

Sunrise -Beach Front- king size, tour Coiba Island

Sunrise is a premiere beach house at Lago Bay. Nestled in a garden setting between the beach and lake with walking trails, the Sunrise experience is filled with nature. With a King-sized mahogany bed and spacious living area, it is very comfortable to unwind after Coiba. The kitchen and bathroom are fully equipped with granite counter tops. Sunrise also has a practical work station with Starlink internet. The screen-in porch is great for listening to the ocean or watching the stars.

Superhost
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.85 out of 5 average rating, 26 reviews

Country House in Olá, rivers, waterfalls, Los Picachos

Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Top Guest favourite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 123 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Top Guest favourite
An outdoor terrace is furnished with a sectional sofa in neutral tones and a low coffee table. A potted plant with green leaves and colorful flowers adds a vibrant touch. Large glass doors provide a view into the interior space, inviting natural light.
Villa in Lagartero
5 out of 5 average rating, 63 reviews

Private Villa & Pool, in Lago Bay, Santa Catalina

A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.

Guest favourite
A wooden deck extends from the entrance, featuring two chairs positioned to enjoy the outdoor environment. The entrance leads into a well-lit interior space, framed by lush greenery that enhances the tranquil setting.
Cabin in El Valle de Antón
4.87 out of 5 average rating, 126 reviews

5 min from Valle I Vista 1 Cabin - Free coffee

🌿 Cabaña Moderna en la Naturaleza – Cerca de El Valle • 🏡 Cabaña moderna rodeada de naturaleza • 📍 A 5 min de Valle de Antón • 🛏️ Espacio tipo estudio: camas, cocina y desayunador integrados • 🍳 Estufa eléctrica (sin horno) y cafetera • 📺 TV • 🌄 Terracita con linda vista • 🐶 Hasta 2 perros pequeños permitidos • 🚗 Pasan todo tipo de auto (ultimos 3 minutos es calle de piedra) • 🫒 Café, azúcar, sal, pimienta, crema y aceite de oliva de cortesía • 🕒 3 pm | 🕛 12 md

Guest favourite
A modern living area features a light-colored sofa and a wooden coffee table. Large glass sliding doors provide a clear view of the ocean and greenery outside. A decorative plant adds a touch of nature, while soft light fills the space.
Apartment in Rio Hato
4.94 out of 5 average rating, 86 reviews

Ocean View Marina Stay in Buenaventura | By Alura

Enjoy an exceptional stay in this elegant and modern apartment, located on the top floor in the marina in Buenaventura, Panama’s most exclusive beach resort. It offers panoramic views of the Pacific Ocean and the Marina. The apartment is fully equipped with high-quality furniture and finishes, thoughtfully designed to provide both comfort and style. You’ll also have access to beach clubs, restaurants, and more, for a truly unforgettable resort experience.

Top Guest favourite
Home in Canto del Llano
4.92 out of 5 average rating, 25 reviews

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Guest favourite
Farm stay in Santa Fe
4.9 out of 5 average rating, 312 reviews

Cabin of the Sun in Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Top Guest favourite
A spacious exterior view of the loft @ Londolozi showcases a two-story structure with a red-tiled roof. Large glass doors open to a patio area with lounge chairs and a hammock, surrounded by lush greenery and mountains in the background.
Cottage in Sorá
4.95 out of 5 average rating, 118 reviews

Luxury Private Cottage in Altos del Maria

This property is situated within the gated community of Altos del Maria. Surrounded by lush forest and rivers, the loft @ Londolozi is for guests who appreciate a sense of luxury while being close to nature. While Altos del Maria enjoys a warm tropical climate, there is a cooling breeze in the mountains that is not often present in the coastal areas.

Top Guest favourite
Condo in Rio Hato
5 out of 5 average rating, 20 reviews

Luxury 2 Bedroom Condo, Playa Blanca Resort

Stunning Airbnb by Wynter Rosegold Designs, defined by her signature style of plush comfort, nature-inspired palettes, and ambient lighting. From beds you’ll never want to leave and thoughtful details for every need, her spaces are unique, functional, warm and luxurious. Wynter’s motto: "Creating a space you never want to leave."

Popular amenities for Santa María holiday rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María