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Hotels in Santa Cruz de la Sierra

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Quick stats about hotels in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 100 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at $14 AUD per night before taxes and fees

  • Verified guest reviews

    Over 190 verified reviews to help you choose

  • Family-friendly holiday rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 10 rentals that welcome pets

  • Holiday rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    60 properties have a dedicated workspace

  • Wi-Fi availability

    100 of Santa Cruz de la Sierra holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Santa Cruz de la Sierra rentals

Top-rated hotels in Santa Cruz de la Sierra

Guests agree: these hotels are highly rated for location, cleanliness and more.

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A spacious hotel room is featured, showcasing a seating area with a circular dining table and a sofa. Large windows allow natural light to enter, providing views of the surrounding area. The sleeping area includes a large bed and a wall-mounted flat-screen TV.
Hotel room in Centro

"Feel at Home"Breakfast buffet !

The room is in the heart of the financial and business district of Santa Cruz ,just a few minutes walk from the main square of the city .Guest will find many shops , supermarket and restaurants nearby and places to go out at night ,only 5 minutes walk from accommodation . Featuring free wifi ,free parking,air conditioning , private bathroom ,cable , american breakfast free of charge ! Guest can relax by the pool , the jacuzzi or make use of the sauna .Fitness facilities are also available!

LocationFamilyHot tub

4.52 out of 5 average rating, 33 reviews
A spacious bedroom features a king sized bed dressed in neutral linens, complemented by decorative pillows. A large window offers ample natural light, while a wall-mounted television and a dark wood dresser add functionality. A small seating area is set beside the window.
Hotel room in Warnes

Sun Hotel, Santa Cruz

This is a timeshare property that we have access to via Interval International. Therefore, check-in is only authorised on specific days, and total days spent in this resort are restricted to 6 days/nights. Check-in day(s): Saturday Sun Hotel is set amid lush greenery and located opposite Viru Viru International Airport. Accommodations are 54 spacious suites. On-site are amenities including sports fields and recreation areas, a fitness center, business center, and saunas and massage areas.

Hotel room in Centro

Comfortable room near the city centre

Enjoy comfort and a strategic location just 2 blocks from the Tahuichi Aguilera Stadium. This private room with a double bed is ideal for couples or business travelers. The residential complex is secure and has Wi-Fi, Smart TV and a private bathroom. An unbeatable location close to public offices, businesses, and a diverse food scene. Enjoy our common areas and 24/7 reception. Your ideal stay in Santa Cruz starts here! Book today for a comfortable experience.

ValueGetting aroundHospitality

New place to stay
A spacious bedroom is furnished with a large bed, accented by a red decorative runner. Two elegant chairs flank a small round table, enhancing the inviting ambiance. Soft lighting from two lamps creates a cozy atmosphere, with light-colored curtains softly framing the windows.
Hotel room in Centro

Imperial King Room

Welcome to the Hotel Lido in Santa Cruz, Bolivia! Our mission at the Hotel Lido is to provide our guests with an exceptional experience that they will never forget. Prime location, exceptional service, delicious cuisine, comfort and safety! We hope your stay at the Hotel Lido will be an unforgettable experience full of comfort and authenticity. We can't wait to welcome you and show you Bolivian hospitality at its finest. Welcome to Santa Cruz!

A cozy private room features a spacious bed with a blue throw blanket. Light-colored linens are complemented by a vibrant blue geometric accent wall. Two wall-mounted lamps provide soft lighting, and large windows allow natural light to fill the space.
Hotel room in Centro

Centrally located private room, Downtown Santa Cruz

Imagine waking up every morning in a cozy LP® room, where we have brought the beauty of Santa Cruz inside the hotel with typical plants and trees that will immerse you in the nature of the region. Surrounded by greenery and freshness.🌿🏝️ In addition, our altarpiece, handmade by a talented Bolivian artist, captures the majesty of the Tajibos and Toborochis trees, adding even more charm to your experience. 🎨🌺

ValueLocationHospitality

4.71 out of 5 average rating, 14 reviews
The exterior of the Hotel Radisson is shown, featuring a modern design with sleek lines. The building is illuminated by neon signage, while large glass windows reflect the evening sky. Palm trees are positioned in the foreground, adding a touch of greenery.
Shared hotel room in Santa Cruz de la Sierra

Suite in Hotel

🏨 Suite at Radisson Hotel – Porongo, Santa Cruz Enjoy a private suite at the Radisson Hotel, just 15 minutes from downtown. Ideal for 2 people, with a choice of a king or two twin beds. Includes American breakfast, WiFi, air conditioning and parking. Full access to common areas: pool on the terrace, jacuzzi, gym and international restaurant. Supermarkets and restaurants nearby.

HospitalityCleanliness

Hotel room in Santa Cruz de la Sierra

Residential

Residencial Bolivia is a simple and cosy accommodation, ideal for people looking for a quiet and accessible place to stay in Santa Cruz. We offer rooms with smart TVs, fans, private bathrooms and air conditioning. A location near one of the largest shops in the city, Barrio Lindo. It's a practical option for short or long stays, with a safe and functional environment.

Location

Hotel room in Santa Cruz de la Sierra

2BR Apartment | TRYP Santa Cruz | Outdoor Pool

TRYP by Wyndham Santa Cruz is located near the city center and financial district, ideal for both business and leisure stays. This superior studio features a queen bed and a streamlined layout designed for comfort and convenience. Guests are near the top attractions, including the Santa Cruz Municipal Zoo, the Museum of Contemporary Art, and Plaza 24 de Septiembre.

Hotel room in Centro

New: Cathedral Views + Buffet Breakfast + King Bed

Pascana Plaza Hotel welcomes you in the heart of Santa Cruz de la Sierra, with a prime location near the city's main attractions, restaurants and shops. It offers spacious, comfortable, and elegant spaces, ideal for couples, business travelers, or those who want to discover Santa Cruz on foot and enjoy a practical, quiet, and well-located stay.

New place to stay
Hotel room in Santa Cruz de la Sierra

Residencial Nube 69

24/7 support. We are located 5 minutes from Viru Viru Airport. Our hotel has comfortable and safe rooms. Private bathroom, air conditioning, wifi, cable TV, 24/7 security for your peace of mind, ample parking. Transportation service, restaurants, shops, pharmacies, medical center minutes from our location.

ValueLocationAccuracy

4.5 out of 5 average rating, 4 reviews
A spacious hotel room features a large bed adorned with crisp white linens. A desk and chair are positioned beside a large window, allowing natural light to brighten the space. Warm tones are present in the decor, complemented by soft lighting fixtures.
Hotel room in Colinas del Urubó

Luxurious Hotel Suite

Suite in a 5-star hotel Super king size bed, modern bathroom, access to sauna, jacuzzi, gym and pool with endless views of the Pirai River Buffet breakfast included Valet parking There is an international restaurant in the hotel

ComfortHospitalityCleanliness

5.0 out of 5 average rating, 4 reviews
Guest favourite
An aerial view of a modern high-rise building surrounded by a lush green landscape. The multi-story structure features a sleek glass façade, reflecting the sunlight, and is positioned near a tree-lined area, providing a natural contrast to its contemporary design.
Hotel room in Santa Cruz de la Sierra

Costanera Suites

Costanera Suites discover a world-class experience, where modern design and hospitality combine to give you an unforgettable stay. Strategically located, ideal for business and leisure getaways.

LocationHospitalityNearby

5.0 out of 5 average rating, 5 reviews

Popular amenities for Santa Cruz de la Sierra hotels

KitchenWi-FiPoolFree parking on premisesAir conditioning

Family-friendly hotels

Hotel room in Valle Sánchez

Premium M & G Accommodation

New place to stay
A bright bedroom features a spacious bed with a quilted white cover and a cozy seating area with a navy couch. Large windows allow ample natural light to fill the room, revealing views of the surrounding cityscape. A wooden wardrobe and bedside table are also visible.
Hotel room in Centro

Hotel Victoria

A front desk area is featured, with a polished granite counter and a staff member on the phone. Bright lighting illuminates the space, revealing a computer screen in the backdrop. Fresh flowers are arranged nearby, adding a touch of warmth to the environment.
Hotel room in Centro

Single Room

The image showcases a well-lit room featuring a spacious bed and a mounted television. Viewers can see a window allowing natural light, with light-colored curtains framing it. A small table and two chairs are positioned in one corner, and an open closet with wooden doors is visible.
Hotel room in Centro

Good rest

LocationConditionHospitality

4.0 out of 5 average rating, 4 reviews
A three-story building is shown, featuring a terracotta façade with large windows covered by sheer curtains. Balconies extend from the upper floors, and the ground level displays various storefronts with roll-down shutters. Power lines are visible overhead against a clear blue sky.
Hotel room in Centro

Hotel 7 streets from downtown

Hotel room in Centro

Double rooms!

Hotel room in Santa Cruz de la Sierra

Hotel BV

A room is presented with two twin-sized beds, each topped with decorative pillows. A flat-screen TV is mounted on the wall. Natural light enters through a window adorned with sheer curtains, while a wooden chair and a small table are positioned in the corner.
Hotel room in Centro

Hotel California

Hotels with a pool

A spacious rooftop area features comfortable lounge beds arranged alongside a clear glass railing. The horizon is filled with soft shades of purple and pink as sunset approaches. A serene pool area is visible, adding to the tranquil ambiance of the space.
Hotel room in Colinas del Urubó

Double Room at Hotel Radisson Santa Cruz

Indoor spacesBreakfastComfort

Hotel room in Centro

A very comfortable and safe place

LocationComfort

A modern bedroom features a spacious bed with neutral bedding and decorative pillows. A mirrored wardrobe reflects the light and ample space. Natural light filters through sheer curtains, adding brightness to the room, while air conditioning is mounted above for comfort.
Hotel room in Santa Cruz de la Sierra

Ortiz Suites

A spacious room features a comfortable bed centered under an ornate ceiling light. Wooden accents complement the decor, and a sitting area includes a small dining table beside glass doors leading to a balcony. A decorative mirror and a television are positioned against the wall.
Hotel room in Centro

Family Room in the Center

A spacious bedroom features a large bed with multiple pillows against a soft beige headboard. Two bedside lamps illuminate the space, and a plush chair is situated in the corner, complementing the warm wooden cabinetry.
Hotel room in Santa Cruz de la Sierra

5-star hotel - Bolivia

A well-lit bedroom features a spacious bed with a patterned red and cream bedspread. Bright curtains frame a window, allowing natural light to fill the room. A bedside table with a lamp and a mirror adds functional elegance to the space.
Hotel room in Santa Cruz de la Sierra

Comfortable and modern place

A cozy bedroom features a standard bed adorned with soft pillows and a blanket. Natural light filters through the floor-to-ceiling curtains, which add a warm touch. A bedside table is positioned beside the bed, contributing to the room's functionality.
Hotel room in Santa Cruz de la Sierra

Suite Rental

A modern building façade showcases a blend of dark stone and green vertical gardens. The entrance is framed by low-growing plants, and the name 'BELLINI' is displayed prominently on the building's exterior. Large windows provide a contemporary aesthetic.
Hotel room in Santa Cruz de la Sierra

Furnished Apartments

Hotels with a patio

A double room features a spacious bed with a grey quilted cover, complemented by soft lighting from a wall fixture. Floor-to-ceiling windows offer natural light and access to a private balcony, with sheer curtains partially drawn to the side.
Hotel room in Santa Cruz de la Sierra

Deluxe Room with Balcony

A modern bedroom features a spacious bed with crisp white linens. A flat-screen television is mounted on the wall opposite the bed. Soft lighting is provided by bedside lamps, and warm wooden flooring adds to the inviting ambiance.
Hotel room in Colinas del Urubó

Hotel in Santa Cruz - Bolivia

A spacious bedroom features a large bed with white linens, complemented by two bedside lamps. A window with sheer curtains allows natural light to fill the room. A chair and small table are positioned near the window, and a television is mounted on the wall.
Hotel room in Santa Cruz de la Sierra

5-star Radisson Hotel, buffet breakfast included

A spacious hotel room features a large bed dressed in crisp white linens. A comfortable armchair is positioned beside a window with sheer curtains, allowing natural light to filter in. A wall-mounted television and a small desk complete the contemporary decor.
Hotel room in Colinas del Urubó

Suite Hotel Radisson

A modern bathroom is equipped with a spacious glass shower enclosure and a stone vanity. The sink features a sleek faucet, and a large mirror is mounted above the counter, enhancing the room's bright ambiance. Soft towels are neatly arranged nearby.
Hotel room in Centro

Hotel in the city center

LocationTVBathroom

Hotel room in Santa Cruz de la Sierra

Suite with kitchen

A bright room features a spacious bed with crisp linens, complemented by a television mounted on a dark wood unit. A small circular table and chair are positioned near the window, which is adorned with flowing red curtains, allowing natural light to fill the space.
Hotel room in Santa Cruz de la Sierra

residencial mia Comfort Room

The entrance to the building is highlighted by a concrete overhang supported by two columns. Large glass doors provide access, flanked by two air conditioning units. Symmetrical windows can be seen above the entrance, with greenery from a nearby plant enhancing the exterior.
Hotel room in Centro

Roma 2 Estrella's Hotel

Destinations to explore