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Holiday houses in Santa Cruz de la Sierra

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A modern bedroom is featured with a spacious bed adorned in neutral tones. Two framed artworks are displayed above the headboard. Natural light enters through large glass doors that open to a private balcony, showcasing views of the surrounding city.
Apartment in Santa Cruz de la Sierra
4.96 out of 5 average rating, 79 reviews

Cozy Apt with A/C, WiFi, Washer, Kitchen, Pool.

✨ Modern and cozy apartment with comfort and a great location. Enjoy the pool, balcony with view, and Smart TV with Netflix, Disney+ and Tigo Sports to relax after a day in the city. ✔ Fast Wi‑Fi ✔ A/C in living room and bedroom ✔ Equipped kitchen: microwave, coffee maker, blender ✔ Welcome treats: coffee, drinks & snacks ☕🍫 ✔ Washing machine, iron, hair dryer ✔ Pool and barbecue ✔ Private access & 24/7 security 📍 In Equipetrol, near 2nd ring and minutes from downtown, cafés and supermarkets

Top Guest favourite
The living area features a comfortable couch positioned near a large window, allowing natural light to fill the space. A flat-screen television is mounted on a wood-paneled wall, and a small round table is visible nearby. The view showcases the city skyline and nearby greenery.
Condo in Santa Cruz de la Sierra
5 out of 5 average rating, 16 reviews

Luxury, comfort, ideal location

Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

Guest favourite
A modern living area features a comfortable dark leather sofa facing a large flat-screen television. A decorative coffee table sits in front of the sofa, with a potted plant nearby, and the room is illuminated by soft ceiling lights, offering views of the surrounding city through expansive windows.
Condo in Santa Cruz de la Sierra
5 out of 5 average rating, 14 reviews

Green Tower - Luxury Apartment

Welcome to the most exclusive address in Santa Cruz—Green Tower. Located in the heart of the city’s top neighbourhood. This high-rise 16th-floor apartment offers breathtaking views over Urubo and Equipetrol. Enjoy a rooftop pool, sauna and top-rated bars and restaurants just an elevator ride away. With 24/7 concierge and security to ensure both comfort and safety throughout your stay. The ideal choice for travelers seeking comfort, privacy and premium access in Bolivia’s economic capital.

Guest favourite
An infinity pool reflects the city skyline, featuring sleek high-rise buildings in the background. The pool's calm waters create a serene environment, while green foliage frames the area, enhancing the visual appeal of this outdoor space.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

Cinematic view, spacious, bathtub, balcony and garage

Upon entering, you appreciate the elegance and style of decoration, high ceilings that provide a feeling of spaciousness and luminosity. The living room is spacious and comfortable, with a luxury built-in kitchen that adds a touch of warmth and elegance. Social areas to impress, with designer and high quality furniture. Churrasquera and a wonderful infinity pool. But what really stands out about this apartment is the breathtaking view that is enjoyed from the terrace or the balcony.

Guest favourite
A modern condominium building is situated at the corner of a quiet street, featuring multiple floors with large balconies. Green landscaping surrounds the property, and a clear blue sky provides a bright backdrop, highlighting the building’s contemporary architecture.
Loft in Santa Cruz de la Sierra
4.91 out of 5 average rating, 178 reviews

Modern Studio Apartment near Zoo - Fast WiFi

Bienvenido a tu hogar en Santa Cruz! Disfrutá un monoambiente moderno, seguro y totalmente equipado, a pasos del Zoológico. Ideal para parejas, ejecutivos o nómadas digitales. Ofrecemos Internet de alta velocidad, estación de trabajo, cocina equipada y atención personalizada para una estadía inolvidable. Ubicación estratégica en zona tranquila, con self check-in y WiFi rápido. Totalmente equipado y perfecto para largas estadías, garantizando tu confort y seguridad. Te esperamos!

Top Guest favourite
Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 26 reviews

Green Tower - 26th Floor Spectacular Views

Enjoy your stay in the highest airbnb in Santa Cruz, and in the best building in the city, in the facilities you can enjoy Pool, Steam Sauna, spectacular views from the 26th floor to the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from the supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 8 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Luxury suite in Green Tower – Santa Cruz 22nd Floor. Live in the tallest and most exclusive building in the city, on the 22nd floor, with panoramic views of Manzana 40, the ecological cordon and the Urubó. Enjoy world-class cuisine in the same building, at Jardines de Asia, Caudilla, and the impressive Sky Bar, as well as free access to the pool, sauna, barbecues and the Sport Motion gym. A new apartment! Furnished with high-end pieces, including a large sofa bed.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.92 out of 5 average rating, 38 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top Guest favourite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 34 reviews

Elegante departamento familiar en Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Condo in Santa Cruz de la Sierra
4.88 out of 5 average rating, 228 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 109 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Apartment in Santa Cruz de la Sierra
4.9 out of 5 average rating, 105 reviews

Hermoso Apartamento 1 dormitorio Equipe

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Popular amenities for Santa Cruz de la Sierra holiday rentals

Quick stats about holiday rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 4,530 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at $15 AUD per night before taxes and fees

  • Verified guest reviews

    Over 51,720 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,260 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 1,160 rentals that welcome pets

  • Holiday rentals with a pool

    3,130 properties feature pools

  • Rentals with dedicated workspaces

    2,560 properties have a dedicated workspace

  • Wi-Fi availability

    4,200 of Santa Cruz de la Sierra holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

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