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Holiday houses in Santa Cruz de la Sierra

Find and book unique accommodation on Airbnb

Quick stats about holiday rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 4,380 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at $14 AUD per night before taxes and fees

  • Verified guest reviews

    Over 59,960 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,170 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 1,180 rentals that welcome pets

  • Holiday rentals with a pool

    2,980 properties feature pools

  • Rentals with dedicated workspaces

    2,510 properties have a dedicated workspace

  • Wi-Fi availability

    4,040 of Santa Cruz de la Sierra holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

Top-rated holiday rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 3 reviews

Luxury and views in Mar Adentro

Treat yourself to a getaway without leaving the city and experience Mar Adentro from this spacious apartment in the newest and most exclusive tower. Wake up to a beach view, unwind on your private terrace with a BBQ, and enjoy an elegant lounge with Bose sound, a 70-inch TV, streaming and internet. Includes a fully equipped kitchen, a bedroom with a walk-in wardrobe and an en suite bathroom, a washing machine, and free parking. Enjoy access to the beach, restaurants, a tiki bar and water activities for your relaxation.

Superhost
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 3 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Diseñado para huéspedes de gustos exigentes que buscan una experiencia superior a un hotel 5 estrellas. Ubicado en Equipetrol, la zona más exclusiva y segura de Santa Cruz, este elegante Dpto. en penúltimo piso ofrece doble balcón con vistas únicas! Premium amenities como sky pool, lounge, billar, churrasqueras, gym completo y más! Rodeado de los mejores restaurantes, bares, cafés, teatros, tiendas y centros empresariales. Ideal para viajes ejecutivos, escapadas de lujo o estadías inolvidables.

Superhost
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 4 reviews

POX | Green Tower - 21 | Luxury with Private Grill

Vive una experiencia de lujo absoluto en este exclusivo departamento en el piso 21 de la emblemática Green Tower. Diseño elegante y vistas panorámicas de la ciudad. Disfruta de una sala sofisticada, comedor de alto nivel, cocina totalmente equipada y un balcón privado con CHURRASQUERA PROPIA, un lujo único en las alturas. El edificio ofrece, piscina, sauna, áreas sociales y seguridad 24/7, restaurantes y bares. Nos encargaremos que tengas una estadía memorable. Descansa - Disfruta - Repite Pox

Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Beautiful, spacious and unique apartment in the best area.

Crea recuerdos inolvidables en este alojamiento único y familiar. Excepcional dpto. de 122 m2 en el corazón de Equipetrol. Lugar muy tranquilo para descansar o trabajar, pero a la vez cerca de la diversión. Pasarás una increíble estadía! Dpto. amplio, moderno, amoblado y decorado, A/C, Wifi, Smartv 4k 65' y 55', cocina, 2 dormitorios, 3 baños, área de lavado y secado propio, amplio parqueo gratuito en la entrada las 24 horas. Hermosa Piscina y sauna. Gran balcón con linda vista a la ciudad.

Superhost
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 4 reviews

Exclusive 2-bedroom apartment, 21st floor, Mare – Equipetrol

Hospédate en este elegante departamento de 2 dormitorios en el piso 21 de Mare, condominio premium en Equipetrol. Cuenta con balcón privado y vista hacia una de las zonas más exclusivas de Santa Cruz, cerca de Manzana 40 y Green Tower. Ideal para viajes de negocios o descanso con parqueo. El departamento ofrece el balance ideal entre confort y sofisticación, con amenities de primer nivel para disfrutar al máximo tu estadía: piscina, jacuzzi, gimnasio, churrasqueras, salas de cowork y más.

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 18 reviews

POX | Green Tower 17th Floor, Luxury in Equipetrol

✨ Vive la experiencia POX de lujo y confort en el corazón de Equipetrol ✨ Ubicado en el piso 17 de la exclusiva Green Tower, este departamento POX Glam combina diseño moderno, decoración sofisticada y una vista panorámica única de Santa Cruz. Perfecto para viajeros de negocios, parejas o estadías de placer que buscan un espacio premium con todas las comodidades. En POX no solo alquilamos departamentos: te damos un hogar lejos de casa. Nuestro equipo está disponible 24/7 para ayudarte.

Guest favourite
A spacious bedroom features a large bed with neutral-toned linens, complemented by bedside tables and soft lighting. Floor-to-ceiling windows frame views of greenery, allowing natural light to fill the room. A simple area rug adds warmth to the polished tile floor.
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 57 reviews

Luxurious stay at modern apartment (Equipetrol)

Astounding apartment furnished to an impeccable standard. It’s the ideal retreat for an exquisite & up-scale stay, located close to the absolute heart of Santa Cruz in one of its finest neighbourhoods. We believe it’s the ultimate location to experience Santa Cruz the way it should be. Get ready to get inspired! Very close to some fabulous sites. All in all, guaranteed enjoyment and relaxation. All day long. Settle in by zoning out with a small company in a professionally cleaned home.

Superhost
Apartment in Santa Cruz de la Sierra
4.84 out of 5 average rating, 31 reviews

Penthouse on Avenida Beni

This is the one! Located minutes from restaurants, shopping, and downtown, it doesn't get much more convenient than this! With a fully equipped kitchen, comfortable bedrooms and a cozy environment Step into this apartment and let the cozy surroundings instantly appeal to you! Here you will find everything you need to make this your home away from home. From the thoughtful decor and thoughtful furnishings, this place has been designed to make everyday life beautiful.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 72 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Superhost
Apartment in Santa Cruz de la Sierra
4.5 out of 5 average rating, 4 reviews

Balcony on 17th floor / Desk / Swimming pool / Gym

Meters from the 2nd ring, Equipetrol area, many restaurants, shops, supermarkets, gyms among others. With a balcony and a view of the 17th floor, pool, work area, gym and others in the social areas. Apartment with: -WiFi 100Mbps - Kitchen - Washing machine -Smart TV - Equipped bathroom - Bed - Pull-out sofa - 100 Mbps Wi-Fi In the building you will have: -swimming-pool - Gym - Sauna - Work area - Games area Live the experience and book ya!

Guest favourite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 15 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

Guest favourite
Apartment in Santa Cruz de la Sierra
4.92 out of 5 average rating, 12 reviews

VistaLux - Equipetrol Studio

Welcome to a sophisticated space at the top. This exceptionally cozy and elegant studio apartment on the 9th floor invites you to experience luxury and warmth at its finest. Are you ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss this unique opportunity. Book now and let yourself be seduced by the charm of this incomparable space!

Popular amenities for Santa Cruz de la Sierra holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.

  • What are the best things to do in Santa Cruz de la Sierra with kids?

    Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.

  • What are some family activities we can do in Santa Cruz de la Sierra?

    Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.

  • What are some of the best day trip ideas from Santa Cruz de la Sierra?

    Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.

  • Are there any pet friendly accommodations available in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.

  • What are some local tips for visiting Santa Cruz de la Sierra?

    Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.

  • What is Santa Cruz de la Sierra known for?

    Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.

  • What are the best hidden gems to explore in Santa Cruz de la Sierra?

    Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.

  • What are the best foods to try in Santa Cruz de la Sierra?

    Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.

  • What should I bring for a trip to Santa Cruz de la Sierra?

    Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.

  • What is the nightlife in Santa Cruz de la Sierra like?

    Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.

  • What are the most popular events or festivals in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.

  • Are there family friendly vacation rentals in Santa Cruz de la Sierra?

    Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.

  • When is the best time to visit Santa Cruz de la Sierra?

    Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.

Destinations to explore