
Holiday houses in Santa Cruz de la Sierra
Find and book unique accommodation on Airbnb
Quick stats about holiday rentals in Santa Cruz de la Sierra

Total holiday rentals
Explore 4,380 holiday rentals in Santa Cruz de la Sierra

Nightly prices starting at
Santa Cruz de la Sierra holiday rentals start at $14 AUD per night before taxes and fees

Verified guest reviews
Over 59,960 verified reviews to help you choose

Family-friendly holiday rentals
1,170 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 1,180 rentals that welcome pets

Holiday rentals with a pool
2,980 properties feature pools

Rentals with dedicated workspaces
2,510 properties have a dedicated workspace

Wi-Fi availability
4,040 of Santa Cruz de la Sierra holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

4.7 Average rating
Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests
Top-rated holiday rentals in Santa Cruz de la Sierra
Guests agree: these stays are highly rated for location, cleanliness and more.

Skyline Luxury • Rooftop, Piscina, Billar & Lounge
Diseñado para huéspedes de gustos exigentes que buscan una experiencia superior a un hotel 5 estrellas. Ubicado en Equipetrol, la zona más exclusiva y segura de Santa Cruz, este elegante Dpto. en penúltimo piso ofrece doble balcón con vistas únicas! Premium amenities como sky pool, lounge, billar, churrasqueras, gym completo y más! Rodeado de los mejores restaurantes, bares, cafés, teatros, tiendas y centros empresariales. Ideal para viajes ejecutivos, escapadas de lujo o estadías inolvidables.

Beautiful, spacious and unique apartment in the best area.
Crea recuerdos inolvidables en este alojamiento único y familiar. Excepcional dpto. de 122 m2 en el corazón de Equipetrol. Lugar muy tranquilo para descansar o trabajar, pero a la vez cerca de la diversión. Pasarás una increíble estadía! Dpto. amplio, moderno, amoblado y decorado, A/C, Wifi, Smartv 4k 65' y 55', cocina, 2 dormitorios, 3 baños, área de lavado y secado propio, amplio parqueo gratuito en la entrada las 24 horas. Hermosa Piscina y sauna. Gran balcón con linda vista a la ciudad.

Exclusive 2-bedroom apartment, 21st floor, Mare – Equipetrol
Hospédate en este elegante departamento de 2 dormitorios en el piso 21 de Mare, condominio premium en Equipetrol. Cuenta con balcón privado y vista hacia una de las zonas más exclusivas de Santa Cruz, cerca de Manzana 40 y Green Tower. Ideal para viajes de negocios o descanso con parqueo. El departamento ofrece el balance ideal entre confort y sofisticación, con amenities de primer nivel para disfrutar al máximo tu estadía: piscina, jacuzzi, gimnasio, churrasqueras, salas de cowork y más.

Penthouse on Avenida Beni
This is the one! Located minutes from restaurants, shopping, and downtown, it doesn't get much more convenient than this! With a fully equipped kitchen, comfortable bedrooms and a cozy environment Step into this apartment and let the cozy surroundings instantly appeal to you! Here you will find everything you need to make this your home away from home. From the thoughtful decor and thoughtful furnishings, this place has been designed to make everyday life beautiful.

Mare Residence · Piso 15 · Monoambiente
Disfruta una estadía moderna en Mare, uno de los edificios más exclusivos de Santa Cruz. Este elegante monoambiente en piso 15 ofrece vista a la ciudad, balcón privado, cama de 2 plazas y sofá cama para hasta 3 huéspedes. Cuenta con Smart TV, Netflix, WiFi, aire acondicionado, cocina equipada, horno y microondas. Disfruta áreas sociales tipo resort con piscina de 30m, cowork, bar, billar, áreas verdes y excelente ubicación cerca de restaurantes y centros comerciales.

aEquipetrol Elite: Your Luxury and Stylish Getaway
Experience luxury and comfort! Welcome to Sky Elite, where design and functionality come together to offer you a unique experience. This elegant, fully equipped studio has been designed for your comfort and lifestyle. Enjoy exclusive amenities: a panoramic pool, jacuzzi, sauna, games room, gym, cinema, co-working space and more. Security 24 Hrs Just a short walk from the best restaurants, cafes and entertainment venues. Book now to experience luxury and comfort!

Green Tower Luxury Studio w/ Pool & Coworking
Bienvenido a un espacio que combina elegancia y comodidad en el corazón de Equipetrol. Rodeado de cafés, restaurantes con auténticas propuestas gastronómicas. Su ubicación estratégica, te permitirá descubrir con facilidad las mejores zonas de la ciudad. En este loft encontrarás un equilibrio perfecto entre comodidad, estilo y ubicación. Ideal tanto para turismo, una escapada tranquila o un viaje de negocios. Te esperamos para que disfrutes de una estancia única.

apartment with an excellent view
Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Elegant in Nanotec
Welcome to our elegant and automated apartment, located in the heart of the most exclusive area of Santa Cruz. This space has been designed to offer a unique experience of comfort and style. Access to the swimming pool, gym, and coworking with other high-level common areas. Located near the city's best restaurants, malls, and attractions, you'll have everything you need at your fingertips. Book now and live the luxury experience in Santa Cruz de la Sierra!

13° SmartLife - Luxury Equipetrol
Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

xEquipetrol Norte, 2 Bedrooms + Pool + Balcony
Experimienta Equipetrol Norte, la zona más exclusiva y vibrante de la ciudad. Disfruta de un alojamiento lleno de detalles, amplio, con balcón. Ideal para largas estadias, viajes en grupo o familia. Relájate en la piscina panorámica, disfruta la churrasquera con vistas espectaculares o aprovecha el coworking, ideal para combinar descanso y productividad. Una estadía pensada para disfrutar cada momento con estilo y confort.

Modern 2BR/2BA in Equipetrol + Pool
Modern 2BR/2BA apartment in the heart of Equipetrol, just half a block from Av. San Martín. Prime location surrounded by top restaurants, coffee shops and malls in Santa Cruz de la Sierra. Bright, comfortable and fully equipped, ideal for business or leisure stays. Enjoy access to a pool and all the amenities needed for short or long stays in one of the city’s most exclusive areas.
Popular amenities for Santa Cruz de la Sierra holiday rentals
Other great holiday rentals in Santa Cruz de la Sierra

Luxury apartment in Zona Norte with two garages

Beautiful Apartment In Equipetrol

Moderno Dpto. en Equipetrol | Self Check-in 24/7

Comfortable apartment in Luxe Suites, Equipetrol

The best view of Santa Cruz

Luxury and comfort in every detail

Elegant family apartment in Equipetrol

Balcony on 17th floor / Desk / Swimming pool / Gym
Frequently Asked Questions
What are the best places to stay in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.
What are the best things to do in Santa Cruz de la Sierra with kids?
Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.
What are some of the best things to do in Santa Cruz de la Sierra?
Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.
How is the weather in Santa Cruz de la Sierra?
Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.
What are the best places to visit in Santa Cruz de la Sierra?
Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.
What are some hiking trails in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.
What are some family activities we can do in Santa Cruz de la Sierra?
Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.
What are some of the best day trip ideas from Santa Cruz de la Sierra?
Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.
Are there any pet friendly accommodations available in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.
What are some local tips for visiting Santa Cruz de la Sierra?
Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.
What is Santa Cruz de la Sierra known for?
Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.
What are the best hidden gems to explore in Santa Cruz de la Sierra?
Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.
What are the best foods to try in Santa Cruz de la Sierra?
Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.
What should I bring for a trip to Santa Cruz de la Sierra?
Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.
What is the nightlife in Santa Cruz de la Sierra like?
Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.
What are the most popular events or festivals in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.
Are there family friendly vacation rentals in Santa Cruz de la Sierra?
Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.
When is the best time to visit Santa Cruz de la Sierra?
Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.
Destinations to explore
- Family-friendly rentals Santa Cruz de la Sierra
- Rentals with a patio Santa Cruz de la Sierra
- Rentals with a sauna Santa Cruz de la Sierra
- Hotel rooms Santa Cruz de la Sierra
- Rentals with a hot tub Santa Cruz de la Sierra
- Rentals with breakfast Santa Cruz de la Sierra
- House rentals Santa Cruz de la Sierra
- Rentals with an EV charger Santa Cruz de la Sierra
- Pet-friendly rentals Santa Cruz de la Sierra
- Serviced apartment rentals Santa Cruz de la Sierra
- Condo rentals Santa Cruz de la Sierra
- Rentals with lake access Santa Cruz de la Sierra
- Beachfront rentals Santa Cruz de la Sierra
- Rentals with a fireplace Santa Cruz de la Sierra
- Apartment rentals Santa Cruz de la Sierra
- Rentals with a fire pit Santa Cruz de la Sierra
- Rentals with pools Santa Cruz de la Sierra
- Rentals with a home theatre Santa Cruz de la Sierra
- Rentals with outdoor seating Santa Cruz de la Sierra
- Fitness-friendly rentals Santa Cruz de la Sierra
- Loft rentals Santa Cruz de la Sierra
- Guesthouse rentals Santa Cruz de la Sierra
- Rentals with beach access Santa Cruz de la Sierra
- Smoking-friendly rentals Santa Cruz de la Sierra
- Rentals with a washing machine and dryer Santa Cruz de la Sierra
- Villa rentals Santa Cruz de la Sierra





