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Holiday houses in Santa Clara

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Top-rated holiday rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Apartment in Panamá
4.98 out of 5 average rating, 230 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top Guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guesthouse in El Valle de Antón
4.99 out of 5 average rating, 114 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top Guest favourite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guesthouse in Gamboa
4.94 out of 5 average rating, 80 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Guest favourite
An outdoor space features a heated pool surrounded by light-colored tiles. A covered patio includes modern seating arrangements and a table, suitable for dining. Lush greenery is visible beyond the walls, with a glimpse of the sky above, providing a bright and open feel to the area.
Home in Vacamonte
5 out of 5 average rating, 33 reviews

The Hidden Gem

Here you will find your home away from home in this hidden gem. Furnished with all of the creature comforts, you will have plenty to do from relaxing on the patio while listening to music, to taking a dip in the heated pool, to relaxing on the comfy couch and watching Netflix. The house is situated on a beautiful gated beach property where you can find various activities from kayaking to the local water park. You can find the relaxation you were searching for here in this hidden gem.

Guest favourite
Apartment in Veracruz
4.89 out of 5 average rating, 9 reviews

On the beach. Entire floor with oceanfront terrace

On the beach with direct access to the sea. Open space studio for 2 people. Living room / kitchen / bedroom 1 (Queen) / sofa / armchair / bathroom with shower, dedicated work space. Large, spectacular terrace on the gulf with bathtub convertible into a sofa. Comfortable, elegant, quiet, and safe. Large and fresh tree-lined garden with tropical fauna and flora. Hummingbirds, iguanas, sometimes monkeys and sloths etc ... Gym equipment, small pool. Perfect for recharging your batteries.

Guest favourite
A scenic view is presented from the balcony, showcasing lush greenery and the town of Gamboa. The Panama Canal and distant hills are visible under a bright sky filled with clouds. A hummingbird feeder is hung nearby, attracting local wildlife.
Cottage in Gamboa
4.77 out of 5 average rating, 56 reviews

Gamboa rainforest lodging

Our restored canal zone home sits on a cul-de-sac in historic Gamboa. It is surrounded by trees and overlooks the town with Panama Canal and passing ships in the distance. An original Damon Kyllo mural adorns one large wall. You will love the balcony, high ceilings, artwork, breezes, and the cacophony of frogs, monkeys, and parrots. This is a great place for birdwatchers and a starting point for exploring the Panama Canal, Soberanía National Park, and the Chagres River.

Guest favourite
Apartment in Panamá
5 out of 5 average rating, 14 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Top Guest favourite
Loft in Panama City
5 out of 5 average rating, 16 reviews

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.93 out of 5 average rating, 136 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Superhost
Home in Brisas del Golf de Arraijan
4.77 out of 5 average rating, 30 reviews

Casa Esmeralda, Cozy for an Ideal Stay.

Casa Esmeralda is a spacious, comfortable, and cozy family home, ideal for families or groups looking for rest, privacy, and a great location. It features 3 bedrooms and 2 bathrooms, with bright, well-designed spaces created to make you feel at home from the very first moment. Located just 45 minutes from Panama City, in a quiet and easily accessible area, it’s perfect for combining relaxation and convenience.

Guest favourite
Apartment in Panamá
4.99 out of 5 average rating, 138 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Top Guest favourite
A modern apartment building is presented, featuring a well-maintained pool area in the foreground. Multiple lounge chairs and tables are arranged neatly around the pool, which reflects the blue sky above. The building showcases large windows, enhancing natural light throughout its levels.
Apartment in La Chorrera
4.91 out of 5 average rating, 47 reviews

The best getaway place in Panama

Enjoy the charmed Panama from our beautiful apartment in Costa Verde, La Chorrera. 30 minutes away from Panama City and 30 minutes away from tipical Panama provinces. Walk distance to the mall, banks, restaurants, pharmacies, stores and much more. Perfect place for you to enjoy all places of Panama. Relax with the whole family at this peaceful place to stay.

Popular amenities for Santa Clara holiday rentals

  1. Airbnb
  2. Panama
  3. Distrito Arraijan
  4. Santa Clara