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Guesthouse holiday rentals in Pima County

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Pima County

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite
A bright main room features a spacious bed dressed in a vibrant yellow and white blanket. Comfortable seating options, including a pair of light-toned sofas, are arranged around a wooden table. Natural light filters through partially covered windows, enhancing the welcoming atmosphere.
Guesthouse in Tucson
4.99 out of 5 average rating, 298 reviews

RetroTrek Bungalow Private-Fenced-Cozy

Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Top Guest favourite
Guesthouse in Tucson
4.97 out of 5 average rating, 447 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top Guest favourite
A cozy living area features a light-colored sofa and two blue accent chairs. A round coffee table sits in the center, with a wooden TV stand showcasing a vibrant piece of art. Large windows provide natural light and overlook the landscaped outdoor space.
Guesthouse in Tucson
4.99 out of 5 average rating, 159 reviews

Peaceful Desert Oasis in Central Tucson Foothills

Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Top Guest favourite
A modern studio guesthouse is set amidst a serene desert landscape, surrounded by various native cacti and shrubs. A mix of green and gray vegetation covers the ground, contrasting with the gravel driveway leading to the entrance. Majestic saguaro cacti tower nearby under a partly cloudy sky.
Guesthouse in Tucson
4.99 out of 5 average rating, 449 reviews

Studio in the Saguaro Forest

New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

Top Guest favourite
The guesthouse is set against a backdrop of desert landscape, showcasing a simple, earthy exterior. A wooden porch with railings invites guests to enjoy the outdoor space. Desert vegetation, including cacti and shrubs, enhances the natural surroundings, along with rocky pathways leading to the house.
Guesthouse in Tucson
4.99 out of 5 average rating, 359 reviews

West-side Trailhead Retreat in the Sonoran Desert

2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Top Guest favourite
A scenic view of the Santa Catalina Mountains under a partly cloudy sky is presented. The landscape is characterized by rolling hills and desert vegetation, with a dirt road leading into the distance. The tranquil atmosphere is enhanced by the natural surroundings.
Guesthouse in Tucson
4.99 out of 5 average rating, 229 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Top Guest favourite
The exterior of the Time Capsule is displayed, featuring a circular design with vibrant purple walls and a wooden deck. Two orange chairs are positioned on the deck, surrounded by desert vegetation. The minimalist structure is set against a clear blue sky.
Guesthouse in Tucson
4.99 out of 5 average rating, 399 reviews

Time Capsule in the Sonoran Desert

Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Guest favourite
The exterior of the guest house is showcased, featuring crisp white walls and a modern blue roof. Large windows allow natural light to illuminate the entrance, which is bordered by minimalist plants in black pots. A concrete porch extends across the front.
Guesthouse in Tucson
4.89 out of 5 average rating, 268 reviews

Newly Constructed Downtown Guesthouse

This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

Top Guest favourite
A comfortable living area is presented, featuring a brown leather sofa opposite a circular wooden coffee table. A colorful area rug adds texture to the floor, while a floor lamp and a large mirror enhance the inviting ambiance. Bright yellow curtains frame a nearby window.
Guesthouse in Tucson
4.98 out of 5 average rating, 488 reviews

The Southwest Knest

Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Top Guest favourite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson
4.96 out of 5 average rating, 887 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top Guest favourite
A serene entryway is framed by a large, leafy tree, with a light green door visible in the center. A brick path leads to the entrance, surrounded by vibrant greenery, cacti, and decorative stones. A seating area is positioned to one side, enhancing the natural atmosphere.
Guesthouse in Tucson
4.99 out of 5 average rating, 255 reviews

Saguaro Oasis Retreat near National Park

If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Guest favourite
A small bedroom features a single bed dressed in a blue and white patterned quilt. A simple wooden dresser is positioned beside the bed, and a woven placemat rests on the dresser's surface. A lamp provides soft lighting, with a wall shelf visible in the background.
Guesthouse in Tucson
4.77 out of 5 average rating, 105 reviews

Tiny House in Central Tucson

A great location in central Tucson in an artists sculpture garden. Private and quiet, in a friendly Enclave. Bathroom is shared, and 2 outdoor kitchens are shared. Patio dining areas available, completely furnished, Wifi, microwave, fridge, appliances, and close to coffee shop, restaurants, three major hospitals, and the University. Sorry, but it's not available for couples. Please introduce yourself - thanks much!

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