
Guesthouse holiday rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Pima County
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Reflection House
This beautifully remodeled guest casita is centrally-located within Tucson. Walking distance to the Tucson Mall, the loop, many restaurants and parks. The gated community has a community pool/spa and dog run. The inner courtyard has a many plants and beautiful large quartz rocks. As you walk into your private entrance Studio you will see tile plank floor, a queen bed, 55in curve tv, dresser and a little desk. This room also has a kitchenette with quartz countertop and luxurious private bathroom.

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Studio in the Saguaro Forest
New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Private Tucson Desert Guest House Getaway
This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Dream House
Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Newly Constructed Downtown Guesthouse
This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Time Capsule in the Sonoran Desert
Vibrant space-age cabin on an 11-acre desert art sanctuary near Saguaro National Park, 35 mins from Tucson! Features WiFi, AC/heat, outdoor bathroom deck & eco-amenities. Sits 15 yards from Groovy Glamper. 🚫 NO PETS/ESAs (Service Animals welcome). Delicate art decor makes this space strictly UNSUITABLE for children/minors. ⚠️ IMPORTANT: Before booking, note that check-in is strictly in person and no later than 10:00 PM. No exceptions!

Saguaro Courtyard Retreat near National Park
If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.
Popular amenities for Pima County guesthouses
Family-Friendly guesthouses

Extra-Spacious 1BR Guesthouse Close to UA

Charming Private Oasis Casita with Pool & Hot Tub

Pet Friendly Casita with striking Mountain View’s

Charming, Cozy Casita with Pool - low summer rates

Golden moments in Oro Valley/Tucson

The Southwest Knest

Charming U of A Area Guesthouse

Casita with Heated Salt Water Pool & Solar Power
Guesthouses with a patio

Rustic Cabin with Mountain Views Close to Wineries

RetroTrek Bungalow Private-Fenced-Cozy

Gorgeous Guest House: private Yard lot of parking

Southwest Solitude

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Sunshine Loft

The Coop- Luxury guest house with ideal location

Amazing Casita at the Tubac Resort-Self check-in*
Guest house rentals with a washing machine and dryer

Cozy midtown guesthouse

Coyote Cavern: A Southwestern High Desert Retreat

Little Hummingbird House -An Enchanted Food Forest

Charming Southwest Casita in East Tucson

Support Local! - 1 Bedroom Detached Bungalow

Blue Lake Boutique Hotel

🌵 Central Desert Oasis 2 🌵

Peaceful, quiet getaway
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- University of Arizona
- University of Arizona
- Tumamoc Hill
- Arizona-Sonora Desert Museum
- Tucson Botanical Gardens
- Titan Missile Museum
- Reid Park Zoo
- Tucson Convention Center
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Rialto Theatre
- Children's Museum Tucson
- Tumacacori National Historical Park
- Mini Time Machine Museum of Miniatures
- Trail Dust Town
- Picacho Peak State Park
- Mercado San Agustin
- Tubac Presidio State Historic Park
- Tucson Mountain Park
- Gene C Reid Park
- Rooster Cogburn Ostrich Ranch
- Red Hills Visitor Center
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