
Guesthouse holiday rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Pima County
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Studio in the Saguaro Forest
New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Cozy Mountain Retreat w/ Hot Tub
Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Time Capsule in the Sonoran Desert
Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Newly Constructed Downtown Guesthouse
This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

The Southwest Knest
Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Saguaro Oasis Retreat near National Park
If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Tiny House in Central Tucson
A great location in central Tucson in an artists sculpture garden. Private and quiet, in a friendly Enclave. Bathroom is shared, and 2 outdoor kitchens are shared. Patio dining areas available, completely furnished, Wifi, microwave, fridge, appliances, and close to coffee shop, restaurants, three major hospitals, and the University. Sorry, but it's not available for couples. Please introduce yourself - thanks much!
Popular amenities for Pima County guesthouses
Family-Friendly guesthouses

Charming Private Oasis Casita with Pool & Hot Tub

Cozy midtown guesthouse

Cozy hideaway cottage in historic Ajo

The Cottage

Oasis: Casita Colibrí - Little Hummingbird House

Cute eco-built guesthouse

Cozy Desert Foothills Getaway

Casita Chapulin
Guesthouses with a patio

Coyote Cavern: A Southwestern High Desert Retreat

Guest Cottage located near University and Downtown

Spacious peaceful guesthouse

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Historic University area Downtown 4th Ave Studio!

The Tucson Bohemian Retreat w/Private Fenced Yard

Sunshine Loft

Casita with Heated Salt Water Pool & Solar Power
Guest house rentals with a washing machine and dryer

The Outpost

Solar Powered Guest House Near UA—No Cleaning Fee!

Eco-Chic Studio Casita | Near UA, 4th & Dog Park

The Copper Casita

Centrally Located Guest House with a View

Blue Lake Boutique Hotel

Golden moments in Oro Valley/Tucson

Mi Casita in Historic Downtown
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- University of Arizona
- Children's Museum Tucson
- Arizona-Sonora Desert Museum
- Tucson Botanical Gardens
- Reid Park Zoo
- Titan Missile Museum
- Tumamoc Hill
- Mission San Xavier del Bac
- University of Arizona
- Kino Sports Complex
- Tucson Convention Center
- Gene C Reid Park
- Tumacacori National Historical Park
- Trail Dust Town
- Rialto Theatre
- Pima Air & Space Museum
- Mini Time Machine Museum of Miniatures
- Tucson Museum of Art
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