
Guesthouse holiday rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Pima County
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Amazing Casita at the Tubac Resort-Self check-in*
Take it easy at this unique and tranquil getaway in the beautiful and historic Tubac Golf Resort. Located in a quiet neighborhood just a 5 minute walk to resort amenities including, spa, salon, resort shops, and Stables restaurant. Our Guesthouse includes a king bed, Sofa bed, personal driveway to park your car, private entrance, beautiful terrace, fireplace, Smart TV, internet, coffee maker, microwave, and mini refrigerator. Known as a center of art and history, is truly worth the visit.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

HummingBird Casita at Birdsong Retreat
Your private studio casita at Birdsong Desert Retreat: thoughtfully curated eclectic furnishings & decor, full kitchen, private bath—opening to serene desert views. Welcome with homemade grain-free granola, pancake mix, syrup, coffee & teas. On 40 peaceful acres: 360° vistas of Patagonia, Atascosa Mtns, Coronado Forest, Mt Wrightson & Mexico. Lake 6 min away. Dark-sky compliant—profound starry nights, nature sounds, monsoon storms & rainbows (Jul-Sep) for renewing energy. More at birdsongaz

Time Capsule in the Sonoran Desert
The Time Capsule is a unique experience in a space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design, we cannot accept any pets in the Time Capsule. However, service animals are welcome. Please note that check-in is in-person only and not later than 10:00 PM.

Southwest Solitude
Experience the best of Tucson. This welcoming retreat is designed with comfort in mind. Enjoy the unique blend of midcentury Tucson and Southwest flair. It is conveniently located on a quiet cul-de-sac near Tucson’s most beloved attractions. It features private off-street parking and entrance, an inviting patio, and a full kitchen to help you feel at home. Make your stay in Tucson truly unforgettable. Book now and start planning your perfect desert getaway at this peaceful retreat.

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Coop- Luxury guest house with ideal location
This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

TREAT GUEST HOUSE Private, Quiet, Comfortable
Welcome to a one-of-a-kind guesthouse created by a Swiss-born professional photographer and freelance artist. This attractive open studio space is part of my "Gesamtkunstwerk" (entire body of work), still in flux. Featuring murals and curated pieces from across a lifelong creative journey. Thoughtfully designed with passion and purpose, the space offers both inspiration and comfort in the heart of Tucson.

Horse house
Welcome to your perfect getaway! This house is located in the heart of the city, giving you easy access to the best restaurants, shops, and local attractions. Enjoy the comfort of modern design with all the amenities you need for an unforgettable stay. The property has private parking, ideal for peace of mind, and a large outdoor space where you can relax, organize meetings, or simply enjoy the outdoors.

Extra-Spacious 1BR Guesthouse Close to UA
Charming guest casita in historic mid-town neighborhood, perfect for short- or long-term stays. Its location 5-7 blocks from University of Arizona and Banner University Medical Center makes it super convenient for grad students, visiting professors and researchers, snowbirds, or vacationers. The nearby streetcar and bus routes provide easy access to downtown attractions.
Popular amenities for Pima County guesthouses
Family-Friendly guesthouses

Cottage of Pomona

Cozy midtown guesthouse

Cozy Mountain Retreat w/ Hot Tub

Charming, Cozy Casita with Pool - low summer rates

Spanish Bungalow Casita with Private Patio

Cozy Thunder Mountain Ranch bunkhouse experience

Charming U of A Area Guesthouse

Casita with Heated Salt Water Pool & Solar Power
Guesthouses with a patio

Coyote Cavern: A Southwestern High Desert Retreat

Guest Cottage located near University and Downtown

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Central Casita Minutes from UA & Downtown

The Tucson Bohemian Retreat w/Private Fenced Yard

Sunshine Loft

Book NOW-your poolside paradise awaits

Midtown-New Constr/Hot Tub/Full Kitchen/Private
Guest house rentals with a washing machine and dryer

Studio w/parking, walk to UA & Banner

Peaceful Desert Oasis in Central Tucson Foothills

Solar Powered Guest House Near UA—No Cleaning Fee!

Blue Lake Boutique Hotel

🌵 Central Desert Oasis 2 🌵

Peaceful, quiet getaway

Privacy, security, comfort, solar! Dog friendly!

The Cottage
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- University of Arizona
- University of Arizona
- Arizona-Sonora Desert Museum
- Tumamoc Hill
- Tucson Botanical Gardens
- Reid Park Zoo
- Titan Missile Museum
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Tucson Convention Center
- Rialto Theatre
- Mini Time Machine Museum of Miniatures
- Children's Museum Tucson
- Picacho Peak State Park
- Tumacacori National Historical Park
- Trail Dust Town
- Tubac Presidio State Historic Park
- Mercado San Agustin
- Gene C Reid Park
- Tucson Mountain Park
- Rooster Cogburn Ostrich Ranch
- Red Hills Visitor Center
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