Guesthouse holiday rentals in National City

Guesthouse in Spring Valley

4.99 out of 5 average rating, 419 reviews

Casita•Views•Outdoor Cinema• SoakTub+Zoo add-on

Escape to a private canyon retreat overlooking 30 acres of scenic hillsides just 20 minutes from Downtown San Diego, CA ✦ Private Hot Soaking Tub ✦ Outdoor Movie Theater ✦ Panoramic Sunset & City Views (west facing) ✦ Entire casita - no shared walls, or above/below units ✦ Exclusive amenities - just for you! ✦ Fast Wi-Fi ✦ 50" Smart TV ✦ Quiet A/C & Heat ✦ Private Patio ✦ Gated offstreet parking A perfect retreat for those wanting a special getaway on a very unique property overlooking the city

The exterior of a historic stone cottage showcases a rounded structure with large, circular windows. Native plants and decorative rocks surround the entrance, highlighting the natural landscape. The name 'Anna' is displayed on a rustic wooden sign, further enhancing the cottage's character.

4.9 out of 5 average rating, 457 reviews

Anna's Historic Stone Cottage w/panoramic View!

Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!

A cozy bedroom is highlighted by a spacious bed adorned with a bright yellow knit blanket. Framed photographs of palm trees and cityscapes decorate the walls, while bedside lamps provide soft illumination on either side of the bed.

4.95 out of 5 average rating, 240 reviews

Central Guest House with Private yard

Enjoy a private, fully equipped guesthouse for two in central San Diego — professionally cleaned, thoughtfully hosted & designed for a comfortable stay. Full kitchen, washer/dryer, filtered RO water & a fenced backyard with ambient lighting. Keyless entry keeps arrival simple & secure. Quick access to freeways. Within 15 minutes of the airport, Gaslamp District, Balboa Park, the Zoo, Petco Park, Seaport Village, the Convention Center, and beaches; tucked into a quiet residential neighborhood.

Guesthouse in Spring Valley

4.98 out of 5 average rating, 435 reviews

Airstream•Sauna•SoakTub• Views•Firepit+Zoo add-on

Nestled in a quiet hillside canyon only 20 min from Downtown San Diego, CA, this is a one-of-a-kind glamping retreat! ✦Private Hot Soaking Tub under the stars ✦Panoramic city/sunset views ✦Exclusive amenities ✦Custom wood-fired sauna ✦Golf chipping tee ✦Fast Wi-Fi ✦AC & Heat ✦Gated parking Cozy up by the fire as the city sparkles below or try your swing at the golf tee. Reconnect & recharge in your outdoor hot soaking tub, rain shower & wood-fired sauna - the perfect retreat for nature lovers!

The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.

4.96 out of 5 average rating, 165 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Guesthouse in Chula Vista

The bathroom features a modern design with double sinks set within a marble countertop. Two round mirrors reflect the sleek fixtures. A decorative box holds tissues, while a wall-mounted towel rack and a shower curtain can be seen in the background.

4.85 out of 5 average rating, 126 reviews

King Bed Studio in Chula Vista

Prime location in Chula Vista! Less than 2 miles away from the Gaylord Pacific Resort (10 min drive). Just a 20 min drive to most San Diego hot spots. Private studio with very comfortable king bed. Queen air mattress also available in unit. Modern bathroom with double-sink, standing shower, marble tile countertops. Spacious layout, a dedicated workstation and fast wifi. Prep your morning coffee and simple breakfast in the kitchenette. The mini fridge can store your favorite drinks.

An outdoor dining area features a large wooden table set with decorative dishes and neatly folded napkins. An umbrella provides shade above the table. Surrounding greenery and hanging hammocks create a tranquil atmosphere, while a pergola frames the space, enhancing the inviting outdoor setting.

4.96 out of 5 average rating, 424 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

Guesthouse in National City

An outdoor seating area features a covered gazebo with warm lighting, creating a welcoming ambiance. Surrounding the space are well-maintained grassy areas and neatly arranged stone pathways. Palm trees add a tropical touch against a backdrop of evening clouds and distant city lights.

4.95 out of 5 average rating, 230 reviews

Trendy 1 BR Guesthouse. Great views, no chores.

This is a beautiful 1 bedroom guest house with a new Queen size bed (4/13/2026)and full-size sofa bed. It is close to everything, making it easy to plan your visit. AirPort, Downtown, Coronado, Balboa Park, local beaches, Mexico, and Navy bases are just a few minutes' drive. Private on-site parking. Charge your EV on site. 110v or 220V Don't waste precious time on charging stations. Public transportation as well as plenty of shopping and restaurants within walking distance.

A spacious outdoor deck features comfortable seating arrangements with light-colored cushions, providing a relaxed space for guests. A wooden coffee table sits in the center, surrounded by potted plants and the entrance to the guest house visible in the background.

4.99 out of 5 average rating, 432 reviews

*Private Canyon Retreat: Your Own Guesthouse*

An airy 1BD guest house at the end of a quiet dead-end street that overlooks a tranquil canyon....and an owner that works hard to create a fabulous experience for each guest; not just “another average rental”. With private entrance, full kitchen & bath, and double french doors opening onto a 400 sq ft deck with canyon views, it's the ideal retreat to come back to after exploring San Diego. Come fall in love with your next home away from home!

Guesthouse in National City

A spacious living area features light brown walls and hardwood flooring. A mounted television is displayed on one wall, accompanied by a small coffee table. A dining table with wooden chairs is situated near a window, which is dressed in sheer curtains allowing natural light to filter in.

4.86 out of 5 average rating, 253 reviews

Open concept Guesthouse w/private entrance

Welcome Travelers! We’re thrilled to host fellow Airbnb guests, especially those who love to travel as much as we do. My husband and I have had amazing experiences with Airbnb around the world, and now we're excited to share the beauty of San Diego with you! A few things to note: We live on the property in a completely separate unit with our dog and five chickens.

A modern kitchen is visible, featuring sleek black cabinets and white countertops. Stainless steel appliances, including a gas stove, are present. A small dining area with a black table and checkered tablecloth complements a cozy seating area, illuminated by natural light from large windows.

4.94 out of 5 average rating, 401 reviews

La Mesa Suite

Mi mesa es su mesa, a beautiful newly built home in sunny La Mesa. Easy access to centrally located shopping center, SDSU and up and coming downtown La Mesa. Short drive down the 8 freeway to the mission beach and downtown SD. Includes everything you need in your home away from home while also providing comfort, security and privacy.

The living room features a comfortable sectional sofa adorned with decorative cushions. A round coffee table sits in the center, with teal accents adding a pop of color. A dining area with high chairs is visible, along with a wall mirror reflecting light and spaciousness.

4.9 out of 5 average rating, 133 reviews

Casita Daisy: Refined 1BR Retreat + Kitchen

Casita Daisy: Your cozy San Diego escape! Bright, stylish casita with private patio, kitchenette, fast Wi-Fi, and designated guest parking. Minutes from beaches, Balboa Park, and downtown—perfect for couples or solo travelers seeking comfort and sunshine. Distant views of San Diego Bay.

Popular amenities for National City guesthouses

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-Friendly guesthouses

A well-maintained putting green is surrounded by lush greenery, featuring multiple flags indicating different holes. A sand trap is positioned nearby, and a winding path made of stone leads through the garden space, enhancing the serene outdoor environment.

4.94 out of 5 average rating, 152 reviews

Pool Side Safari Cabin-On the backend of our Home

A charming exterior of a white house is framed by vibrant green plants and orange flowers. A stone pathway leads to an inviting front door, flanked by decorative lanterns. A small dog stands on the path, adding a sense of welcoming to the scene.

4.98 out of 5 average rating, 110 reviews

Enchanting private Mt Helix retreat close to SDSU

4.99 out of 5 average rating, 195 reviews

A bright living area is characterized by large windows that invite natural light and provide views of greenery outside. A wall-mounted TV is positioned opposite a comfortable sofa, while a colorful dining chair adds a playful touch to the space.

Guesthouse in Del Cerro

The Happy Family * 2 playhouses near SDSU!

4.81 out of 5 average rating, 234 reviews

A clean, modern studio features a spacious bed with light blue and white striped bedding. A kitchenette with a microwave and electric burners is equipped with essential utensils. Large sliding glass doors provide access to a private deck, allowing natural light to fill the room.

Guesthouse in Bonita

Private Modern Studio with Ocean View

Two red Adirondack chairs are positioned under a covered patio, facing a serene backyard with a pool. Lush greenery surrounds the area, creating a tranquil atmosphere. A BBQ room and various seating arrangements are visible beyond the pool, enhancing the outdoor retreat experience.

4.99 out of 5 average rating, 171 reviews

Private 1 BR Paradise Retreat

Guesthouse in Greater North Park

A cozy living area is presented with a plush couch and a reading chair, accompanied by a coffee table. A cushioned bed rests within an alcove, framed by soft curtains. Natural light filters through nearby windows, illuminating the warm wooden flooring.

4.91 out of 5 average rating, 663 reviews

Quaint Craftsman#2- Walkable, Parking, EV Charging

4.97 out of 5 average rating, 633 reviews

Guesthouse in Kensington

Peaceful Garden Getaway-Near Downtown & Beaches

A functional kitchen space is showcased with cream-colored cabinetry and a farmhouse sink beneath a window. A VIKING wine fridge is positioned beside the sink, complementing the modern appliances. The counter features a variety of utensils and a plant, adding a touch of greenery.

4.98 out of 5 average rating, 107 reviews

Private 400sf iFULL KITCHENi beautiful cozy 2bed

Guesthouses with a patio

Guesthouse in Rancho San Diego

A welcoming living area features a mix of comfortable seating on a light-toned rug. A round coffee table is centered among the couches, adorned with a decorative tray and fresh flowers. Natural light floods in through the skylights, illuminating the modern decor.

4.98 out of 5 average rating, 100 reviews

Beachy Cottage in the mountains

Guesthouse in Mission Hills

A curving staircase is visible, flanked by white walls and adorned with vibrant blue tiles. Handrails provide support along the ascent, leading to a bright upper space. A potted plant enhances the serene ambiance at the top of the stairs.

5 out of 5 average rating, 260 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

Guesthouse in Pacific Beach

An outdoor terrace features a spacious seating area with plush cushions, a central firepit, and lounge chairs overlooking a panoramic view of the landscape and ocean in the distance. The setting invites relaxation and enjoyment in a serene environment.

4.96 out of 5 average rating, 112 reviews

Beach views for 2! Jacuzzi, fire pit

A spacious deck is visible, furnished with a table and four wicker chairs. A decorative bowl sits at the center of the table. The panoramic view of the surrounding landscape and city skyline stretches into the distance under a clear blue sky.

4.96 out of 5 average rating, 257 reviews

Da Hui Hut - La Mesa’s best view and spa

A cozy sleeping area is presented with a spacious bed covered in light linens. Beside it, a nightstand with a lamp provides soft lighting. A small round table with a plant adds a touch of greenery, and natural light enters through bright windows framed by soft curtains.

4.87 out of 5 average rating, 203 reviews

Downtown Cottage Walkable to Gaslamp & Petco Park

A cozy living area features a sectional sofa and wooden coffee table, complemented by a television mounted on the wall. Several light sources illuminate the space, including a ceiling fan. Decorative wall art adds a personal touch, while windows allow natural light to brighten the room.

4.99 out of 5 average rating, 359 reviews

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

A living area features a cozy orange sofa adorned with colorful pillows. A desk with a green chair is situated near a window covered with vertical blinds, allowing natural light to illuminate the space. An air conditioning unit is mounted on the wall.

4.92 out of 5 average rating, 156 reviews

*KING BED* Colorful Guesthouse by Downtown

Guesthouse in Sunset Cliffs

A scenic view of the ocean is visible from a balcony. Lush greenery and palm trees frame the coastline, while rooftops and solar panels from nearby homes are seen below. The clear blue sky reflects the tranquil ambiance of the surroundings.

4.96 out of 5 average rating, 114 reviews

Guest house with ocean views and private deck.

Guest house rentals with a washing machine and dryer

4.9 out of 5 average rating, 249 reviews

An outdoor patio is surrounded by lush greenery, featuring vibrant flowers and ferns. A rustic wooden feature stands to one side, complementing the warm-toned brick flooring. A large glass door provides access to the interior, inviting natural light into the space.

Guesthouse in Hillcrest

Relaxing Oasis - short walk to shops & recreation

A private deck is shown, featuring a red umbrella over a round table with four chairs. The entrance to the guest house is framed by glass doors and accompanied by a vibrant red door. Lush greenery and flowerbeds enhance the outdoor space.

4.99 out of 5 average rating, 225 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Guesthouse in Greater North Park

The exterior of a renovated guesthouse is presented, featuring a white stucco facade with decorative tiles along the steps. A green door, large windows, and a charming walkway leading to the stairs enhance the inviting appearance of the property.

4.99 out of 5 average rating, 194 reviews

Carrie’s North Park Casita, in Heart of San Diego

4.99 out of 5 average rating, 221 reviews

A welcoming entrance features a textured walkway leading to a front door, framed by a wooden railing. Colorful flowers bloom along the sloped landscape, enhancing the natural appeal of the surroundings. Clear skies and distant homes provide a serene backdrop.

Guesthouse in El Cajon

Modern mountain guest house. Incredible views

A cozy outdoor seating area is framed by large glass windows, offering sweeping views of a vibrant sunset over the landscape. Plush cushions rest on a spacious sofa, inviting relaxation as the sky transitions to hues of orange and pink.

4.99 out of 5 average rating, 108 reviews

AmazingVIEWS! Hilltop Guest House with XL Balcony~

Guesthouse in Greater North Park

A spacious bedroom features a king bed with neutral bedding and decorative pillows. French doors provide natural light and open to a balcony overlooking lush greenery. A modern ceiling fan and soft lighting complement the hardwood floor and simple decor, creating a comfortable and inviting space.

4.96 out of 5 average rating, 217 reviews

New Guest House - North Park

4.98 out of 5 average rating, 251 reviews

A spacious living area is equipped with a plush sofa and light-colored chairs, accented by decorative pillows. A wooden coffee table rests on a colorful area rug. Natural light fills the room through two windows, highlighting a work desk and welcoming artwork on the wall.

Guesthouse in El Cajon

Fletcher Hills - modern 1 BR.Easy, no step access.