Some info is shown in its original language. Translate
Airbnb your place

Boutique hotels in Mississippi River

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Mississippi River

Guests agree: These boutique hotels are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1
Top Guest favourite
A spacious living area features a turquoise tufted sofa and two white armchairs, arranged around a small coffee table. A warm wood fireplace is centered against the wall, topped with a large mirror. Natural light filters through adorned windows, enhancing the elegant decor.
Hotel room in Galveston

Grand Manor Mansion Hotel Emerald King Suite

The Grand Manor Hotel Emerald KING Suite CRUISE TERMINAL4 BLKS Property rated top 5 island accomodation Century old villa blends-old word charm with a fusion of West Indies tropical flare . The Grand Manor has curated a special new offering, and perfect retreat . This King suite features high ceilings , central AC , fine linens, bistro bar & Luxury Amenities and more... Stunning ensuite bath with double doors Best walking location in Historic Downtown 6 other suites on site

4.96 out of 5 average rating, 110 reviews
Top Guest favourite
A spacious guest room is furnished with an antique queen bed and a vintage leather Chesterfield sofa. Natural light filters through the blackout shades, illuminating wooden flooring and a small dresser, while a large window offers a view. A decorative mirror is positioned beside the bed.
Hotel room in Galveston

The Garden Suite | Walk Downtown

One of six rooms at Saint Helens House-Hotel. See all our rooms: www.airbnb.com/p/sthelenshouse This is the downstairs guest room in a multi-room historic guest house. No stairs to climb (except for the front porch stairs) and it's just steps from the kitchen, coffee bar, and back garden. It features an antique queen bed, blackout shades, a vintage leather Chesterfield sofa, and a flat-screen TV. This room includes a private ensuite bathroom with classic black-&-white tile and a walk-in shower.

4.99 out of 5 average rating, 245 reviews
Guest favourite
A spacious room features large windows overlooking Beaver Lake, allowing natural light to fill the space. A cozy sitting area includes a beige sofa and a rustic coffee table, while a queen pillow-top bed is positioned nearby. Accent walls of natural stone add texture to the room.
Hotel room in Eureka Springs

Romantic Lakeview Jacuzzi Suite

Jacuzzi Suites are the size of a hotel room with the privacy of a woodsy cabin. Our suites the perfect way to spend a romantic getaway. Each suite has a queen pillow-top bed, a sitting area, a Jacuzzi for two and a small deck with a stunning view of Beaver Lake. No kitchens; however, each one has a coffee bar w/ mini fridge, microwave and Keurig. Each suite has its own private boardwalk entrance to ensure privacy. We have 3 suites attached to the office building. No pets allowed in the suites.

4.95 out of 5 average rating, 284 reviews
Top Guest favourite
A romantic jacuzzi tub is positioned near a window adorned with stained glass, providing natural light. Two towels are neatly hung on a rack, with wooden accents enhancing the space. A marble countertop with a sink is visible in the foreground.
Hotel room in Eureka Springs

Ozark King - A Private Suite with Eclectic Charm

The Ozark King is a super cute, attic-like suite situated on the top floor of a 1920s Victorian home. It has a private entrance with a king bed, fireplace and romantic jacuzzi tub for two. It offers a snack and coffee station with mini fridge & microwave. There are no shared indoor spaces with other guests. Guests should be aware of 3 short sets of stairs to get up to the top floor and there is limited leg room in the restroom for extremely long-legged persons (manuverable but worth noting).

4.95 out of 5 average rating, 238 reviews
Top Guest favourite
A spacious room features antique stone walls and hardwood flooring. A large wooden bed is flanked by two lamps, with decorative pillows adding color. A seated area includes a soft chair, and a dresser complements the warm, inviting decor.
Hotel room in Eureka Springs

Downtown luxury suite, privacy and convenience!

Relax in a spacious, private suite that allows you to stretch. The Anderson Suite at Twilight Terrace offers 800 gorgeous square feet. Feel right at home with the great Arts and Crafts décor, a kitchenette with fridge and microwave, Wifi and a flat screen TV with cable. The bath boasts a jet tub for 2 and a tiled shower for 2. Antique accents with modern amenities give you a comfortable, luxurious base to enjoy Eureka Springs! Add in OFF-STREET PARKING and you’re set for a fabulous stay!

4.99 out of 5 average rating, 324 reviews
Guest favourite
Hotel room in Hermann

Crown's Flower Suite, Live Music, Right Downtown!

Hermann 1837 Cellar Bar/Restaurant Onsite. Live Music Nightly May-Oct! It’s a Floral Delight in Our Flower Suite. A 2nd Floor Suite Filled with Flowers! Complete with Prints, Framings, and Collectibles Celebrating Flowers. King Bed, Electric Fireplace, Microwave, Mini Fridge, WiFi, & Cable. $20 Personalized All Day Shuttle Service (Trolley is $30). Free Pick Up/Return to Train Station & Free Electric Charging Stations. $50 per pet nightly fee. Free Drink Tickets & Free Buffet Breakfast.

4.93 out of 5 average rating, 114 reviews
Top Guest favourite
The room features a queen size bed adorned with a decorative red and gold coverlet. Two windows are dressed with plush maroon curtains. A dresser with a mirror and a TV are positioned against one wall, while a faux fireplace adds warmth to the inviting space.
Hotel room in Osceola

Historic Commercial Hotel(1868),Sally Rand Suite

The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.

4.93 out of 5 average rating, 120 reviews
Guest favourite
A charming building features a stone exterior with vibrant red doors. Two small sitting areas are adorned with red chairs and a table, surrounded by a lush green plant. A wooden fence lines the property, with a clear blue sky overhead.
Hotel room in Springfield

“The Classic” at Rockwood Motor Court on Route 66.

Rockwood Motor Court, built in 1929, is located on historic Route 66. Each room is themed and furnished to the era of Route 66. “The Classic” showcases the automobiles on road in the 1940’s and 50’s. This room features vintage furniture, a full size bed, bathroom with dressing area, and corner shower. Renovated in 2019, enjoy a clean, comfortable room and experience authentic motor court lodging. Need more space? We also have larger rooms and can package multiple rooms for your group.

4.97 out of 5 average rating, 111 reviews
Guest favourite
A modern, arch-shaped cabin is featured with a black roof and white walls, positioned on a gravel path. Two black chairs are placed in front of the door, and a bike is secured to the wall, emphasizing the cycling theme.
Hotel room in Bentonville

The Bike Inn #15, Kings River Cabin

Welcome to The Bike Inn, Bentonville! The Kings River Cabin is a handcrafted retreat with a Queen Bed, mini fridge, microwave, and Keurig. There’s no connected bathroom, but guests have access to the Guest Lounge & Shower House with a full kitchen, restrooms, sauna, hot tub, and a heated outdoor shower. Enjoy in-room bike storage, a wash & repair station, WiFi, fire pit, gazebo, BBQ, and more. After a day on the trails, unwind by the fire with fellow adventurers. Bike. Sleep. Repeat!

5.0 out of 5 average rating, 40 reviews
Top Guest favourite
The room features exposed brick walls and a wooden ceiling, enhancing the rustic charm. A spacious bed sits beside a cozy seating area with an orange armchair and a guitar. Natural light floods in through multiple large windows, with decorative elements like a cowhide rug and artwork adding character.
Hotel room in Hannibal

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

4.97 out of 5 average rating, 163 reviews
Guest favourite
A well-lit room features a spacious bed topped with white bedding and pillows. A flat-screen TV is mounted on the wall opposite a large mirror, enhancing the sense of space. A sleek bathroom area is visible, showcasing modern fixtures and marble flooring.
Hotel room in Washington

River Sirens Hotel Junior Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Each room is also equipped with a full kitchen featuring large refrigerators with ice dispensers, induction stove top, microwave, toaster, and coffee station.

4.95 out of 5 average rating, 131 reviews
Guest favourite
The spacious room features sloped ceilings and large windows that allow natural light to fill the space. A queen bed draped in a soft coverlet is positioned beside a modern in-room jacuzzi tub. Dark countertops contrast with the light walls, creating a serene atmosphere.
Hotel room in Branson

Lavender Paradise: Room #26 at The Bradford

Come enjoy a relaxing stay at The Bradford! Easy access to the Branson Strip and only 5 minutes from Silver Dollar City! Our rooms are newly remodeled, and each have their own uniqueness. The complimentary coffee bar and game room are everything you need before a fun-filled day in Branson! There’s no other view of the Branson strip quite like The Bradford’s! You won’t want to leave this charming, one-of-a-kind property.

4.82 out of 5 average rating, 219 reviews

Popular amenities for Mississippi River boutique hotels

KitchenWifiPoolFree parking on premisesAir conditioning

Family-friendly boutique hotels

Guest favourite
A round wooden dining table is surrounded by six matching chairs in a sunlit room. Large windows reveal a scenic view of the beach and gulf beyond, with natural light flooding the space. A ceiling fan provides a cooling breeze, enhancing comfort.
Hotel room in Grand Isle

Gulf Front Suite - 2 Bedrooms with Kitchen

4.82 out of 5 average rating, 50 reviews
Guest favourite
A well-lit room features two queen beds, complemented by bedside lamps. A mirrored accent and a flat-screen TV are mounted on the wall. A work desk and chair are positioned next to a small vanity area, with a landscape artwork adding a touch of decor.
Hotel room in Branson

Double Queen room in Branson

4.93 out of 5 average rating, 118 reviews
Guest favourite
Hotel room in Pacific

Queen room for two near wedding venues

4.84 out of 5 average rating, 120 reviews
Guest favourite
A bright room features two spacious beds, each adorned with colorful striped blankets. A decorative area rug with geometric patterns covers the wooden floor. Soft lighting is provided by bedside lamps, and a vibrant wall art piece adds visual interest to the room.
Hotel room in Hot Springs National Park

Room 10 · Holiday Road Room-Dame Fortune’s Cottage Court

4.89 out of 5 average rating, 227 reviews
Guest favourite
A newly renovated motel room displays contemporary decor with a queen bed framed by light-colored walls. Two lamps illuminate the nightstands on either side. A small dining table with two chairs is positioned nearby, and windows adorned with wooden blinds provide natural light.
Hotel room in Superior

Superior Bay Boutique Motel Unit #6

4.87 out of 5 average rating, 356 reviews
Guest favourite
A branch adorned with delicate white flowers is positioned in a vase on a table, creating a soft focal point. In the background, a spacious bed is partially visible, with natural light entering from a window, enhancing the bright interior.
Hotel room in McFarland

301 Evanson's Attic Loft - Queen Bed

4.97 out of 5 average rating, 249 reviews
Top Guest favourite
A modern kitchen area features sleek stainless steel appliances, including a refrigerator and an oven. A wooden dining bar with stools provides seating. A television mounted on the wall is complemented by a small console table with a decorative lamp. A large wall clock adds a stylish touch.
Hotel room in Evansville

Theodore Robinson Suite-Grove Guest House

4.96 out of 5 average rating, 130 reviews
Guest favourite
Hotel room in Grafton

The Deckhouse at Aerie's Resort

4.92 out of 5 average rating, 26 reviews

Boutique hotels with a patio

Guest favourite
A cozy room is styled with rich red walls and a turquoise ceiling. A spacious bed is framed by decorative wooden panels and plush pillows. Two lamps provide soft lighting, and antique mirrors enhance the historic decor. A small air conditioning unit is mounted on the wall.
Hotel room in French Quarter

Historic French Quarter Suite w/ Courtyard

4.84 out of 5 average rating, 179 reviews
Guest favourite
An interior room features a spacious layout highlighted by a king-size bed and a sitting area. Two lamps provide soft lighting beside the bed and in the corner, with a coffee station and a work area visible along one wall.
Hotel room in Laurel

Hotel Pinehurst- Central Ave Suite 208

4.89 out of 5 average rating, 166 reviews
Guest favourite
A spacious king suite features a large bed with soft linens, complemented by a cozy armchair and a stylish lamp. A separate jacuzzi tub is situated nearby, and natural light flows in through the window, illuminating the light-colored decor and wood accents.
Hotel room in New Glarus

Chalet King Suite w/ Jacuzzi

4.93 out of 5 average rating, 123 reviews
Top Guest favourite
A comfortable bedroom features a spacious bed with soft linens and a decorative pillow. French doors lead to an inviting living area. Natural light fills the room through sheer curtains, highlighting the wooden flooring and subtle decor.
Hotel room in Ocean Springs

Mockingbird Inn- Azalea Suite

4.99 out of 5 average rating, 203 reviews
Guest favourite
The spacious common area features an open kitchen with a dark granite countertop, blending modern functionality with historic charm. Two large stained glass windows cast colorful light throughout the room, while a grand staircase leads to an upper level, showcasing the building's architectural elegance.
Hotel room in Dogtown

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

4.98 out of 5 average rating, 63 reviews
Guest favourite
A grand stone structure features a series of arched windows and detailed brickwork. Lush shrubs flank the steps leading to the entrance, which is complemented by a landscaped area of stones and rocks.
Hotel room in New Offenburg

Weingarten Vineyard Luxurious Suite #2

4.96 out of 5 average rating, 47 reviews
Superhost
Hotel room in Eureka Springs

Downtown*Chantilly Ste*Piedmont

4.89 out of 5 average rating, 9 reviews
Top Guest favourite
A spacious bathroom features rustic brick walls and a striking freestanding tub. A glass shower enclosure is situated nearby, with natural light filtering through a textured window. Decorative lighting is integrated into a cozy nook, adding a warm touch to the inviting space.
Hotel room in Saint Charles

#4 Penny Farthing Le Velo Inn

5.0 out of 5 average rating, 60 reviews

Other boutique hotel holiday rentals

Superhost
The room features a spacious bed adorned with a patterned blanket, complemented by a bright artwork above. A warm lamp provides soft light, and a ceiling fan is visible. The room has light blue walls and two windows dressed with light curtains, enhancing the natural light.
Hotel room in Central West End

The Maple Room Queen Bed at BnB in CWE!

4.85 out of 5 average rating, 841 reviews
Guest favourite
Hotel room in Springfield

Culture Boutique Hotel: Casablanca Suite

4.94 out of 5 average rating, 83 reviews
Guest favourite
The historic Wentworth Mansion is presented with a classic brick facade, complemented by white trim and railings. Symmetrical windows adorn the structure, and ascending steps lead to the central entrance, framed by elegant pillars and a covered porch.
Hotel room in Lexington

Wentworth Mansion Suite 1

4.84 out of 5 average rating, 64 reviews
Guest favourite
Hotel room in Hot Springs

Historic Suite w/ Balcony | Walk to Bathhouse Row

5.0 out of 5 average rating, 37 reviews
Top Guest favourite
A cozy living area features a vintage striped sofa paired with a matching curved seat. A small wooden coffee table with decorative items is centered on a colorful area rug, while a lamp provides soft lighting against the deep green wall.
Hotel room in Perryville

The Atrium - A Boutique Hotel - Suite 18

5.0 out of 5 average rating, 23 reviews
Guest favourite
A cozy living area features a red sofa adorned with decorative pillows, paired with a light-colored armchair. A wooden coffee table sits in front, while two windows allow natural light to brighten the space, revealing views of the outdoors.
Hotel room in Grafton

River View Guest House, The Light House

4.93 out of 5 average rating, 28 reviews
Superhost
Hotel room in Duluth

Terrace Suite, Heirloom Hotel Collection

4.92 out of 5 average rating, 95 reviews
Guest favourite
The exterior of the Courtland Hotel showcases red brick architecture, featuring large windows with green trim. A sidewalk runs alongside, complemented by planters and benches, enhancing the inviting atmosphere of the surrounding downtown area.
Hotel room in Fort Scott

Charming Historic Hotel lodging

4.91 out of 5 average rating, 79 reviews

Destinations to explore