
Holiday houses in Mesquite
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Mesquite
Guests agree: these stays are highly rated for location, cleanliness and more.

Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Tiny Cute Cubby in Telshor Hills, Private Entrance
The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Desert Oasis with Pool
Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

The Alamo on Ocotillo
Enjoy this secluded desert oasis at the Alamo on Ocotillo. This fabulous spacious home is nestled in a quiet neighborhood conveniently located less than 2 miles from the university. Relax in the seasonal pool, enjoy time with family and friends in the various cozy outdoor spaces and take in some shopping in old Mesilla. Numerous travelers love to explore the Dripping Springs trails with an invigorating day hike. You'll find this home to be the peaceful "get away" you are looking for.

Casita De Cuervo
Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Cul-de-sac Condo
You'll enjoy staying in this modern townhouse enjoy a glass of wine in the covered patio while taking in the New Mexico sunsets. Pet free, smoke free. Fully equipped kitchen with everything you'll need to prepare meals. Spacious 2 bedrooms , 2 full bathrooms. Smart TV's with Roku, access to garage, washer/ dryer. In friendly quiet cul de sac neighborhood with minimal traffic. Easy access to Interstates 10, 25, and Highway 70. Close to restaurants, movie theater, shopping.

Little House with Private Patio and Hot Tub
Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

1 bed cute casita near NMSU, pet friendly
Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV
Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

4 Bedroom Contemporary Model home
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With 4 bedrooms and plenty of space The Dove Escape offers the comfort of home with a luxury feel. This stylish modern space is perfect for families, groups, or anyone seeking a retreat at the end of long day in Las Cruces or a break from the road. The Dove escape is minutes from NMSU and the University Corridor with all it has to offer.

The Desert Dome @ BNC Farms
Welcome to the Desert Dome! We are located in small village of Chaparral, NM. This is a great spot to get away from the hustle and bustle of life while still having all the city amenities close by. You can find lots of hiking and biking trails in the area. We love furry friends, and would be happy to have your pets here too. There is a fenced in back area for their use. All pets must be leashed if not in the fenced area.
Popular amenities for Mesquite holiday rentals
Other great holiday rentals in Mesquite

Stylish Casa | Mtn Views | Pet-Friendly | 5MinNMSU

Rustic SouthWest Retreat | 4BR| Desert Charm

Casa Majestica

360° Views, Spa, Billiards, Birdwatching, Private

Hidden Las Cruces Retreat

Beautiful Adobe Home

Cozy Las Cruces Home

Payne Place 2
Destinations to explore
- Salt River Holiday rentals
- Tucson Holiday rentals
- El Paso Holiday rentals
- Northern New Mexico Holiday rentals
- Albuquerque Holiday rentals
- Ruidoso Holiday rentals
- Ciudad Juárez Holiday rentals
- Santa Fe Holiday rentals
- Chihuahua Holiday rentals
- Lubbock Holiday rentals
- Nogales Holiday rentals
- Las Cruces Holiday rentals
- White Sands National Park
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- Western Playland
- Sun Bowl Stadium
- El Paso Zoo
- New Mexico Farm & Ranch Heritage Museum
- Southwest University Park
- Hueco Tanks State Historic Site
- El Paso Chihuahuas
- El Paso Museum of Art
- La Rodadora Espacio Interactivo
- San Jacinto Plaza
- Parque Público Federal El Chamizal
- Dripping Springs Natural Area
- Sunland Park Racetrack & Casino
- Farmers And Crafts Market of Las Cruces




